© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Dexibuprofen
Chemical Formula: C13H18O2
CAS Number: 51146-56-6
Synonyms: (S)-(+)-Ibuprofen
Recommended Use: Pharmaceutical intermediate, pain relief medication
Supplier: Pharmaceutical manufacturer or distributor, medical distributor, or research laboratory supplier
Contact Information: Company address, emergency telephone number, specific contact person (safety officer or manufacturer contact)
Emergency Phone Number: Listed phone lines for poison control or hazardous chemical incident teams
Relevant Identified Uses: Production of pharmaceutical tablets, capsules, and syrups for analgesic purposes
Hazard Classification: Not classified as hazardous under GHS criteria for pure solid material, presents low acute toxicity, but extended exposure or large oral doses have risk of complications
Hazard Statements: Can irritate eyes, respiratory tract, and skin, may cause drowsiness, dizziness, or headache with excessive exposure—large doses linked to gastrointestinal effects, allergic skin reactions in sensitive individuals
Signal Word: Warning
Pictograms: Exclamation mark symbol
Precautionary Statements: Avoid inhalation of dust, prevent direct contact with skin and eyes, do not swallow laboratory quantities, keep away from food or beverages in the preparation area
Chemical Name: Dexibuprofen
Chemical Formula: C13H18O2
Purity: Pharmaceutical grade, typically above 98% pure
Impurities: May include trace residuals from synthesis such as solvents, not present in significant amounts
Nature of Substance: White crystalline powder, odorless
Inhalation: Remove to fresh air, keep comfortable for breathing, obtain medical advice if symptoms develop or persist, monitor for cough, chest pain, or respiratory distress
Eye Contact: Rinse thoroughly with plenty of clean running water for several minutes, remove contact lenses if present and easy to do, seek medical attention for persistent irritation, avoid rubbing eyes
Skin Contact: Wash affected skin with soap and water, remove contaminated clothing, rinse thoroughly, see a physician if skin irritation or allergic rash develops
Ingestion: Rinse mouth with water, seek immediate medical help if a large quantity is swallowed inadvertently, discourage vomiting unless advised by medical personnel
Note to Doctor: Treat symptomatically, monitor for signs of gastrointestinal irritation or allergic response, consider effects on liver and kidneys
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, or foam; water spray for larger fires
Unsuitable Media: Avoid high pressure water jets directly on solid product to minimize dust dispersal
Special Hazards: Can emit toxic fumes of carbon monoxide, carbon dioxide upon combustion, dust in confined spaces can form explosive mixtures with air
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective clothing, stay upwind, avoid inhalation of combustion products, decontaminate equipment afterwards
Specific Methods: Remove containers from fire area if safe, cool containers with water spray, prevent run-off from entering drains or watercourses
Personal Precautions: Wear gloves, laboratory coat, goggles, dust mask or respirator as needed, avoid breathing dust, personnel should avoid skin contact
Environmental Precautions: Prevent further leakage or spillage if safe, avoid discharge into drains, soil, or watercourses, report major releases to environmental authorities
Methods for Cleanup: Sweep up with non-sparking tools, transfer carefully to a labeled container for disposal, use damp towels to control dust, ventilate area after clean-up, wash affected area thoroughly to remove residues
Cleaning Materials: Use absorbent, inert material like sand or vermiculite for large spills, dispose of cleaning material as hazardous waste
Safe Handling: Minimize dust generation and accumulation, avoid breathing dust, wash hands after handling, keep container tightly closed, use only in well-ventilated areas, wear suitable personal protective equipment as described below
Storage Conditions: Store at room temperature, keep away from direct sunlight, moisture, excessive heat, acids, and strong oxidizers, use original or compatible containers that are clearly labeled, keep locked up and out of reach of children
Technical Measures: Maintain good local exhaust ventilation, use sealed process equipment where possible, keep storage area dry and well-organized
Incompatibles: Strong acids, oxidizing agents, bases—the material can decompose under extreme conditions
Control Parameters: No established occupational exposure limits for Dexibuprofen, recommended to keep workplace exposure as low as reasonably achievable
Engineering Controls: Use laboratory fume hood, local exhaust ventilation, dust extraction systems in manufacturing or research environments
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile, neoprene), safety goggles, lab coat or apron, dust mask or respirator for significant dust exposure, suitable protective footwear to avoid contact with spilled powder
Hygienic Measures: Wash thoroughly after handling, do not eat, drink, or smoke in work areas, remove contaminated clothing promptly, clean equipment after use
Appearance: White or off-white crystalline powder
Odor: Odorless
Molecular Weight: 206.28 g/mol
pH: Not applicable (insoluble in water)
Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, acetone, and methanol
Melting Point: 52 - 54°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not determined for the solid form
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.17 g/cm³
Partition Coefficient (log Pow): 3.5
Chemical Stability: Stable under recommended storage and handling conditions
Reactive Hazards: No dangerous reactions known under normal use, avoid contact with strong oxidizing agents, acids, or alkalis
Conditions to Avoid: Incompatible chemicals, excessive heat, moisture, high humidity, freezing temperatures
Hazardous Decomposition Products: May produce carbon monoxide, carbon dioxide, irritating and toxic fumes under fire or thermal decomposition conditions
Polymerization: Does not occur
Acute Toxicity: Oral LD50 (rat): > 800 mg/kg, based on related ibuprofen compounds; may cause gastrointestinal symptoms in humans if ingested in large amounts
Skin Irritation: Weak irritant, risk depends on individual sensitivity and duration of contact
Inhalation: Dust may cause respiratory tract irritation; symptoms can include sore throat, coughing
Eye Contact: May cause transient irritation, redness, discomfort
Chronic Effects: Chronic exposure at low levels not expected to present significant risks under proper handling; misuse or large accidental doses can lead to gastrointestinal bleeding, renal and hepatic toxicity
Carcinogenicity: Not listed as carcinogen by IARC, OSHA, NTP
Reproductive Toxicity: No conclusive data for Dexibuprofen, standard dosing not associated with teratogenic effects, high or inappropriate ingestion during pregnancy can carry risks
Sensitization: Rare allergic reactions in sensitive individuals reported in medical literature
Ecotoxicity: Not acutely toxic to aquatic organisms at environmental concentrations, possible long-term effects from large or repeated discharges
Persistence and Degradability: Expected to be only partially biodegradable in the environment, resistant to rapid breakdown
Bioaccumulative Potential: Potential to bioaccumulate in aquatic organisms based on octanol-water partition coefficient
Mobility in Soil: Moderate, unlikely to leach rapidly to ground water, but possible in high concentrations or following spills
Other Adverse Effects: Trace pharmaceutical residues in effluents can affect ecosystems in sensitive species, care required to limit uncontrolled release
Waste Treatment Methods: Collect spilt material and waste in labeled, sealed containers, handle as hazardous chemical waste, use approved incineration or disposal facilities
Contaminated Packaging: Clean containers thoroughly before recycling or disposal, dispose in accordance with local requirements for hazardous packaging
Regulations: Comply with national, regional, and local environmental and safety regulations for pharmaceutical waste; never dispose of via sewage or natural water bodies
Safe Disposal Advice: Consult licensed chemical or pharmaceutical waste contractors for bulk or laboratory disposal
UN Number: Not classified under standard UN recommendations for dangerous goods
Proper Shipping Name: Dexibuprofen, not regulated for ground or air transport under normal quantities
Transport Hazard Class: Not a dangerous good
Packing Group: Not assigned
Environmental Hazards: Avoid uncontrolled release during shipment, use sturdy, sealed containers
Special Precautions: Keep packages intact, dry, away from foodstuffs during transportation, follow current shipping practices for pharmaceuticals
Labelling: Label as per OSHA, CLP Regulation, or local standards for chemicals
Regulation Compliance: Subject to safety standards under national occupational safety laws, environmental regulations for pharmaceuticals, and workplace health protocols
Safety Assessments: Internal workplace risk assessment, periodic review of procedures by qualified safety officers
Other Applicable Requirements: International guidelines (such as ICH Q7 for pharmaceutical quality), workplace monitoring for air quality, local codes for hazardous materials
Worker Training: Provide employees with training in safe handling, exposure response, spill management, and first aid for chemical exposure
