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Material Safety Data Sheet for D-Xylose

Identification

Product Name: D-Xylose
Synonyms: Wood sugar, Xylopyranose
CAS Number: 58-86-6
EC Number: 200-400-7
Recommended Use: Laboratory research, food additive, pharmaceuticals
Supplier Info: Name, address, and emergency contact numbers of the manufacturer or distributor
REACH Registration Number: 01-2120764690-53-XXXX

Hazard Identification

GHS Classification: Not classified as hazardous according to GHS standards
Label Elements: No GHS hazard pictogram required
Signal Word: None
Hazard Statements: This material does not meet criteria for any health or environmental hazard
Precautionary Statements: Avoid breathing dust, minimize contact with skin and eyes, maintain workplace ventilation
Other Hazards: Dust may irritate eyes, skin, respiratory tract; avoid generating high dust concentrations because inhaled particles can irritate airways

Composition / Information on Ingredients

Chemical Name: D-Xylose
Purity: >99%
Molecular Formula: C5H10O5
Molecular Weight: 150.13 g/mol
Impurities: Water, minor sugars (if present in non-pharmaceutical grades), monitored below legal limits
Ingredient Classification: Not classed as hazardous per regulation (EC) No 1272/2008

First Aid Measures

Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting upper and lower lids; seek medical attention if irritation persists
Skin Contact: Wash skin with soap and water, remove contaminated clothing, seek medical attention in case of persistent irritation
Inhalation: Move to fresh air, support breathing if necessary, get medical help in case of symptoms like persistent cough or difficulty breathing
Ingestion: Rinse mouth; drink water if person is conscious and alert; do not induce vomiting unless directed by medical personnel; consult a physician in case of discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, alcohol-resistant foam; select media based on environment
Unsuitable Media: Avoid direct water jets; may cause dust dispersal
Specific Hazards from Fire: Combustible dust can form explosive mixtures in air; thermal decomposition emits carbon oxides
Advice for Firefighters: Wear full protective gear and self-contained breathing apparatus; contain run-off with barriers to prevent environmental contamination
Special Precautions: Remove nearby flammable materials, isolate spill zone, prevent ignition sources

Accidental Release Measures

Personal Precautions: Avoid inhalation of dust, ventilate area, use personal protective equipment (see exposure controls)
Environmental Precautions: Prevent further leakage or spillage; do not flush into surface water or sanitary sewer
Methods for Containment: Sweep up with minimal dust generation, use wet methods if feasible
Cleanup Procedures: Collect in suitable containers for disposal, ventilate affected area, clean residue with water, dispose according to local rules

Handling and Storage

Handling: Avoid contact with eyes, skin, and clothing; do not breathe dust; wash hands thoroughly after use; minimize dust generation by handling in well-ventilated areas
Storage Conditions: Keep container tightly closed, store in a cool, dry location, protect from moisture, separate from incompatible substances like strong oxidizing agents
Specific Uses: Laboratory chemicals, food ingredient, under guidance of qualified personnel
Storage Packaging: Use sealed containers designed for pharmaceutical or food-grade products to prevent contamination

Exposure Controls and Personal Protection

Control Parameters: No occupational exposure limits set for D-Xylose by OSHA or ACGIH
Engineering Controls: Local exhaust ventilation recommended to control airborne dust; maintain air concentrations below nuisance levels (e.g., 10 mg/m3 total dust)
Personal Protective Equipment: Use safety glasses with side-shields, dust mask (P2/FFP2 respirator for high dust), gloves made of chemical-resistant material (nitrile, PVC), standard laboratory coat
Hygiene Measures: Wash hands before eating, drinking, or smoking; avoid transfer from hands to face or mouth
Environmental Exposure Controls: Avoid release of dust to the environment; use spill control procedures to prevent air and water contamination

Physical and Chemical Properties

Appearance: White crystalline powder or granules
Odor: Odorless
Melting Point: 144–146 °C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water (approximately 1.6 g/mL at 25 °C), slightly soluble in ethanol
pH: 5.0–7.0 (10% aqueous solution)
Vapor Pressure: Not measurable at room temperature
Flash Point: Not applicable
Flammability: May form combustible dust concentrations in air, requires ignition temperature
Density: 1.53 g/cm3
Partition Coefficient (n-octanol/water): Data not available
Auto-ignition Temperature: No reliable data
Explosive Properties: Dust can explode under certain conditions; industrial settings should use proper dust controls

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures
Reactivity: No known hazardous reactions under recommended handling conditions
Conditions to Avoid: Avoid dust formation, ignition sources, excessive heat, contact with moisture for prolonged periods
Incompatible Materials: Strong oxidizing agents, strong acids; risk of violent reaction
Hazardous Decomposition Products: Carbon monoxide and carbon dioxide generated during combustion or decomposition

Toxicological Information

Acute Toxicity: LD50 oral (rat): >10,000 mg/kg; not considered toxic based on animal studies
Skin Irritation: Not expected under normal use, but repeated contact can cause mild irritation
Eye Irritation: Dust may cause temporary irritation
Inhalation: Dust can irritate mucous membranes of the nose and throat
Sensitization: No evidence of skin or respiratory sensitization
Chronic Effects: No data pointing to carcinogenic, mutagenic, or reproductive hazards
Other Information: D-Xylose is used in human pharmaceuticals as an oral dose marker, so general population exposure has been well-studied and is considered low risk at product concentrations

Ecological Information

Ecotoxicity: D-Xylose is a naturally occurring sugar, rapidly biodegraded by microorganisms, low risk to aquatic and terrestrial organisms
Persistence and Degradability: Readily biodegradable in soil and water
Bioaccumulation: Potential for bioaccumulation negligible due to rapid breakdown and low lipid solubility
Mobility in Soil: Dissolves in water, moves with rainwater or wastewater
Results of PBT/vPvB Assessment: Does not meet criteria for persistent, bioaccumulative, or toxic substances
Other Adverse Effects: High local concentrations might affect water quality temporarily by increasing biochemical oxygen demand, but this risk is minimal outside of industrial-scale spills

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local regulations; this product is not classified as hazardous waste
Small Spills: Sweep up and place in appropriate waste container for disposal or recycling
Large Volumes: Contact licensed waste disposal contractor
Disposal of Packaging: Empty containers should be rinsed, can often be recycled or disposed of with general industrial waste as allowed locally
Special Precautions: Prevent release to drains, surface water or soil; avoid burning unless permitted by local authorities

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Not applicable (not hazardous material)
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not classified as hazardous to the environment
Special Transport Precautions: Avoid packaging that can break under normal transport conditions, use dry and sealed containers

Regulatory Information

EU Regulations: Not subject to classification or labeling under EU Regulation (EC) No 1272/2008 or REACH Annex XVII
US Regulations: Listed on TSCA inventory, not subject to SARA Title III reporting requirements
Canada: Listed on DSL/NDSL
Other Relevant Legislation: This substance is not classified under GHS as hazardous; no workplace-specific restrictions other than standard dust and hygiene practices
Workplace Regulation: Employers should ensure compliance with local health and safety standards regarding handling of fine organic powders
Food Standard: Permitted in food use under CODEX and many national food codes, subject to purity criteria and allowable exposure limits