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Material Safety Data Sheet for D-Pantothenate Sodium / D-Sodium Pantothenate

Identification

Product Name: D-Pantothenate Sodium / D-Sodium Pantothenate
Chemical Formula: C9H16NNaO5
Synonyms: Calcium D-pantothenate sodium salt, Vitamin B5 sodium salt
CAS Number: 867-81-2
Recommended Uses: Nutritional additive in food and feed, pharmaceutical applications
Supplier: Manufacturer or distributor address and contact details
Emergency Phone: Local emergency number or poison center hotline

Hazard Identification

GHS Classification: Not classified as hazardous according to regulation
Main Hazards: May cause slight irritation to eyes, skin, and respiratory system. Dust may aggravate pre-existing respiratory conditions
Pictograms: None required under GHS
Signal Word: None
Precautionary Statements: Avoid dust generation, avoid contact with skin and eyes, use with proper ventilation
Medical Risk Groups: Individuals with chronic respiratory disorders may experience aggravated symptoms

Composition / Information on Ingredients

Chemical Composition: D-Pantothenate Sodium 98%+, water (≤2%), trace impurities
Component: D-Sodium Pantothenate
CAS: 867-81-2
EINECS: 212-769-1

First Aid Measures

Inhalation: Move affected person to fresh air. Seek medical attention if respiratory symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with soap and plenty of water
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical advice if irritation continues
Ingestion: Rinse mouth with water and consult a physician if any adverse symptoms appear
Advice for Doctor: Treat symptomatically based on patient’s condition and exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Unsuitable Media: Direct water stream may cause spreading of dust
Specific Hazards: Burning produces irritating and toxic fumes, such as carbon oxides, nitrogen compounds, sodium oxides
Protective Equipment: Firefighters need self-contained breathing apparatus and protective gear
Thermal Decomposition: Material can emit hazardous fumes if involved in fire

Accidental Release Measures

Personal Precautions: Avoid dust formation, ventilate the area, use personal protective equipment
Environmental Precautions: Avoid uncontrolled release into soil, drains and waterways
Containment: Pick up powder mechanically and place in suitable container for reuse or disposal
Cleaning Methods: Avoid dry sweeping to reduce dust, use dust suppressant if needed, wash spill area after material removal

Handling and Storage

Precautions for Safe Handling: Use in well-ventilated areas, minimize dust buildup, avoid ingestion and inhalation, wash hands after handling
Storage Conditions: Store in tightly closed original container, in a cool, dry and well-ventilated location
Incompatible Substances: Strong oxidizing agents, strong acids
Technical Measures: Use engineering controls to minimize exposure, keep containers tightly sealed
Packaging Materials: Approved materials for preventing moisture and contamination

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established
Engineering Controls: General mechanical ventilation for dust control
Respiratory Protection: NIOSH-approved dust mask for dusty work
Eye Protection: Safety goggles in areas with risk of dust contact
Skin Protection: Chemical-resistant gloves and protective clothing
Hygiene Measures: Wash hands before eating, drinking, or smoking after handling, keep work clothing separate

Physical and Chemical Properties

Appearance: White, almost odorless crystalline powder
Odor: Nearly odorless
Molecular Weight: 243.22 g/mol
pH (1% Solution): 6.5–8.0
Melting Point: Decomposes above 190°C
Boiling Point: Not applicable
Solubility: Freely soluble in water
Partition Coefficient: Not determined
Flash Point: Not flammable under normal conditions
Auto-Ignition Temperature: Not determined
Vapor Pressure: Not applicable
Relative Density: Approximately 1.4 g/cm³

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Avoid strong acids, strong oxidizers
Conditions to Avoid: Excessive heat, exposure to moisture, direct sunlight
Hazardous Decomposition Products: Carbon oxides, sodium compounds, nitrogen oxides in case of fire
Polymerization: Does not occur

Toxicological Information

Acute Toxicity: Oral LD50 (rat) > 10,000 mg/kg
Skin: No evidence of significant irritation from short-term exposure
Eyes: May cause mild transient irritation on contact
Inhalation: Dust may cause mild respiratory tract irritation
Chronic Effects: No evidence of chronic toxicity or carcinogenicity
Mutagenicity: Not identified as mutagenic or teratogenic in standard tests

Ecological Information

Ecotoxicity: Not expected to be hazardous to aquatic or terrestrial organisms. Any environmental release should still be minimized
Persistence/Degradability: Biodegradable, breaks down in environment over time
Bioaccumulative Potential: Unlikely to accumulate in living organisms
Mobility in Soil: Highly water soluble, can migrate in aquatic environments if released
Other Information: Good manufacturing practice reduces risk of accidental release

Disposal Considerations

Waste Management: Dispose through licensed waste contractor. Follow regional regulations
Recommended Disposal: Large volume: incineration in approved facility. Small amounts: regular landfill with appropriate permits
Contaminated Packaging: Rinse thoroughly before recycling or disposal
Precautions: Avoid contamination of water supplies and natural habitats with material

Transport Information

UN Number: Not regulated
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned
Proper Shipping Name: D-Pantothenate Sodium
Environmental Hazards: Not a marine pollutant
Transport Labels: No specific marking required

Regulatory Information

Inventory Status: Listed on major international inventories (TSCA, EINECS, DSL)
Regulatory Classification: Not a controlled substance
OSHA Hazard Communication: Not classified as hazardous material
WHMIS (Canada): Not controlled
REACH (Europe): Exempt under Annex V, considered safe for use in specified applications
Other Regulations: Always review local, regional and national regulations before handling or disposal