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MSDS for D-Calcium Pantothenate

1. Identification

Product Name: D-Calcium Pantothenate
Synonyms: Calcium-D-pantothenate, Calcium pantothenate, Vitamin B5 calcium salt
CAS Number: 137-08-6
Recommended Use: Food additive, dietary supplement, laboratory reagent
Manufacturer Details: Provided by vendor or supplier
Emergency Contact Number: Refer to local provider or regional poison control center

2. Hazard Identification

GHS Classification: Not considered hazardous under normal usage and handling
Hazard Statements: May cause mild skin or eye irritation in sensitive individuals
Precautionary Statements: Avoid unnecessary contact with eyes, skin, clothing
Pictogram: None applicable for standard handling
Signal Word: None
HMIS Rating: Health: 1, Flammability: 0, Reactivity: 0, Personal Protection: B

3. Composition / Information on Ingredients

Chemical Name: D-Calcium Pantothenate
Molecular Formula: C18H32CaN2O10
Molecular Weight: 476.53 g/mol
Content: Contains ≥98% D-Calcium Pantothenate by weight, trace moisture possible
Impurities: May contain minor amounts of mono-calcium salts and other by-products below safety concern thresholds

4. First Aid Measures

Inhalation: Move individual to fresh air, monitor for signs of irritation
Eye Contact: Rinse cautiously under running water, remove contact lenses if present, continue rinsing until clear
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing
Ingestion: Rinse mouth, drink water to dilute, seek medical advice if large amounts consumed
Symptoms to Watch For: Mild discomfort, redness, watery eyes, cough, rare allergic reactions

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use carbon dioxide, dry powder, or foam extinguishers
Unsuitable Media: High-pressure water jets may spread dust
Specific Hazards: Dust can combust if exposed to strong ignition sources
Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Hazardous Decomposition: Produces carbon oxides, nitrogen oxides, calcium oxide on burning

6. Accidental Release Measures

Personal Precautions: Wear protective gloves, goggles, dust mask, ventilate area
Environmental Precautions: Prevent bulk material from entering drains or waterways
Cleanup Methods: Sweep up spills with minimal dusting, place in secure container for disposal
Reference to Other Sections: Handle as described in Sections on Handling and Exposure Controls

7. Handling and Storage

Handling Practices: Avoid breathing dust, prevent contact with eyes and skin, wear appropriate PPE
Storage Conditions: Store in tightly sealed container in cool, dry, well-ventilated location
Incompatibilities: Keep away from strong acids, alkalis, and oxidizing agents
Special Storage Needs: Protect from moisture and direct sunlight, prevent prolonged exposure to high temperatures

8. Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits established for D-Calcium Pantothenate
Engineering Controls: Use with adequate local exhaust ventilation to minimize airborne particles
Personal Protective Equipment: Gloves, safety glasses, dust mask for individuals with sensitivities
Hygiene Measures: Wash hands after use, do not eat, drink, or smoke while handling, keep work area clean

9. Physical and Chemical Properties

Appearance: White, crystalline, odorless powder
Melting Point: Decomposes upon melting at above 200°C
Solubility: Readily soluble and stable in water, almost insoluble in ethanol and ether
pH: Slightly basic (solution in water)
Bulk Density: Approximately 0.5 g/cm³
Vapor Pressure: Negligible at room temperature
Stability: Stable under recommended storage conditions, slight hygroscopicity possible

10. Stability and Reactivity

Chemical Stability: Stable at room temperature in sealed containers
Reactivity: Non-reactive under normal conditions
Hazardous Reactions: None known under recommended handling
Decomposition Products: Calcium oxide, carbon oxides, nitrogen oxides under excessive heat or fire
Conditions to Avoid: Excessive moisture, high heat, direct exposure to incompatible chemicals

11. Toxicological Information

Route of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Low toxicity with LD50 oral (rat) >10,000 mg/kg
Skin and Eye Contact: Minor irritation possible, no delayed or chronic effects noted
Respiratory Sensitization: Fine dust may provoke mild breathing discomfort in sensitive individuals
Carcinogenicity, Mutagenicity, Teratogenicity: Not classed as carcinogenic, mutagenic, or teratogenic
Other Effects: High exposures not anticipated in typical workplace or consumer environments

12. Ecological Information

Ecotoxicity: Low hazard to aquatic life, no concentration-based aquatic warnings issued
Persistence and Degradability: Biodegradable in the environment, breaks down into non-toxic components
Bioaccumulation Potential: Low potential, expected to pass through ecosystems without significant build-up
Mobility in Soil: High solubility in water, moderate mobility in soils with rapid dilution and degradation
Other Adverse Effects: No identified risks for ozone depletion, photochemical smog, or long-range transport

13. Disposal Considerations

Waste Disposal Methods: Dispose according to local or national regulations for non-hazardous chemical waste
Container Disposal: Empty, rinse, and recycle packaging materials where allowable
Special Precautions: Avoid bulk dumping into drains or waterways; send excess, expired, or unused materials to licensed chemical waste handlers

14. Transport Information

UN Number: Not regulated for transport
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Special Precautions: Protect from moisture, store in sealed packaging during transit
Label Requirements: None required for land, air, or sea shipment under standard conventions

15. Regulatory Information

International Inventories: Listed in EINECS, TSCA, and other national inventories
Regulatory Status: Approved for use in food, supplements, and pharmaceutical formulations, subject to purity and labeling standards
Relevant Legislation: Complies with REACH, FDA, and local safety, health, and environmental regulations for handling and usage
Other Standards: No workplace-specific hazard labeling requirements in most jurisdictions; standard chemical hygiene and labor rules apply