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Chemical Name: Cyclooctane
Synonyms: Octamethylene cycloalkane
CAS Number: 2921-15-7
Appearance: Clear, colorless liquid
Odor: Mild, hydrocarbon-like
Use: Solvent, research chemical, organic synthesis
GHS Classification: Flammable liquid, Acute toxicity (oral, inhalation), Skin and eye irritation
Hazard Statements: Highly flammable, may cause skin and eye irritation, toxic if inhaled, harmful if swallowed
Pictograms: Flame, exclamation mark
Signal Word: Danger
Primary Routes of Entry: Inhalation, ingestion, skin and eye contact
Chemical Composition: Pure cyclooctane
Concentration: Greater than 99%
Impurities: May contain trace levels of related hydrocarbons
Inhalation: Move to fresh air, support breathing as needed. Seek medical help for respiratory symptoms.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing.
Eye Contact: Immediately flush with plenty of water for several minutes. Get medical help if irritation persists.
Ingestion: Rinse mouth, don’t induce vomiting. Get prompt medical attention.
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, or foam.
Unsuitable Media: Water jets may spread the fire.
Special Hazards: Vapors can form explosive mixtures with air. Combustion produces carbon monoxide and carbon dioxide.
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear.
Additional Advice: Cool exposed containers with water spray from a safe distance.
Personal Precautions: Ventilate area, avoid all ignition sources, use personal protective equipment.
Spill Cleanup: Contain and absorb spill with inert material like sand or vermiculite. Collect in suitable containers for disposal.
Environmental Precautions: Prevent release into sewers, watercourses, or soil.
Handling: Work in well-ventilated places, keep away from open flames and heat sources, avoid inhalation and skin contact.
Storage: Store in tightly closed containers, in cool dry areas, grounded and away from incompatible chemicals like strong oxidizers.
Engineering Controls: Use local exhaust ventilation, closed systems for large volumes.
Personal Protection: Use solvent-resistant gloves, splash goggles, and lab coats. In case of inadequate ventilation, wear an approved organic vapor respirator.
Workplace Exposure Limits: No established limits found for cyclooctane itself; general hydrocarbon guidelines apply.
Form: Liquid
Boiling Point: 146–148°C
Flash Point: Around 27°C (closed cup method)
Density: Approximately 0.83 g/cm³
Vapor Pressure: Moderately high at ambient temperature
Solubility: Insoluble in water, readily soluble in organic solvents
Odor Threshold: Not sharply defined, detectable at low concentrations
Chemical Stability: Stable under recommended storage and handling conditions.
Hazardous Reactions: Reacts with strong oxidizers producing combustion products.
Decomposition Products: Burning produces carbon oxides and possibly toxic hydrocarbons.
Conditions to Avoid: High temperatures, flames, sparks, static discharge.
Routes of Exposure: Inhalation, ingestion, dermal, eye
Acute Effects: Can irritate respiratory tract, eyes, and skin. High concentrations may depress the central nervous system and cause dizziness or headache.
Chronic Effects: Extended exposure may cause skin dryness, cracking, or more severe nervous system effects.
LD50 (oral, rat): Information limited; hydrocarbons of similar structure often range from moderate to low acute toxicity.
Carcinogenicity: Not recognized by IARC, NTP, or OSHA as carcinogenic.
Aquatic Toxicity: Harmful to aquatic organisms at certain concentrations, due to low solubility and persistence.
Mobility: Floats on water, evaporates to air; tends not to bioaccumulate heavily.
Degradability: Not rapidly biodegradable; can persist under low-oxygen conditions.
Waste Disposal: Dispose of as a hazardous waste following local and national laws. Do not pour down drains or into natural bodies of water.
Container Disposal: Drain and triple-rinse containers before recycling or disposal. Ensure all labels are removed.
UN Number: 1145
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Shipping Name: Cyclooctane
Environmental Hazards: Not classified as a marine pollutant for transport, yet spills can impact aquatic environments
Special Precautions: Keep containers upright, secured, and away from heat during transport
GHS Status: Meets requirements for flammable liquid with acute toxicity warnings
OSHA: Covered under Hazard Communication Standard
SARA Title III: Not listed as an extremely hazardous substance
Inventory Listing: Listed on TSCA in the United States and similar inventories elsewhere
Other Regulations: Local, state, and international rules may govern storage and handling due to flammability
