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Product Name: Clotrimazole
Chemical Name: 1-(o-Chloro-α,α-diphenylbenzyl)imidazole
CAS Number: 23593-75-1
Recommended Use: Antifungal agent
Supplier Details: Contact details vary by manufacturer
Emergency Contact: Local poison control center or healthcare provider
GHS Classification: Not classified as hazardous according to OSHA Hazard Communication Standard
Label Elements: No pictogram required
Signal Word: None
Hazard Statements: May cause eye or skin irritation, harmful if swallowed in large quantities
Precautionary Statements: Avoid contact with eyes, skin, or clothing, wash hands after handling
Other Hazards: Dust may cause respiratory tract irritation
Chemical Identity: Clotrimazole
Common Name/Synonyms: Lotrimin, Canesten
CAS Number: 23593-75-1
Concentration: Typically 100% in bulk, lower concentrations in formulated products
Inhalation: Move person to fresh air, seek medical attention if symptoms progress
Skin Contact: Wash affected area with plenty of soap and water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for at least 15 minutes, seek medical advice if irritation occurs
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention promptly if a large amount is swallowed
Most Important Symptoms: Mild irritation to eyes, skin, and mucous membranes
Suitable Extinguishing Media: Use water spray, carbon dioxide (CO2), foam, or dry chemical extinguishers
Specific Hazards: Emits toxic fumes (chlorine, nitrogen oxides, carbon oxides) when burned
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing
Special Procedures: Keep run-off water out of sewers and water sources
Personal Precautions: Use protective gloves and goggles, prevent dust formation
Environmental Precautions: Prevent release into the environment, avoid discharge into waterways
Methods for Cleanup: Sweep up powder without generating dust, place in suitable container for disposal, clean spill area with water
Safe Handling: Use with adequate ventilation, avoid breathing dust, prevent contact with eyes and skin
Storage Conditions: Store in a cool, dry, well-ventilated area, keep tightly closed in original container, protect from light and moisture
Incompatible Materials: Strong oxidizing agents
Exposure Limits: No specific occupational exposure limits set
Engineering Controls: Use local exhaust or general room ventilation
Eye Protection: Safety goggles recommended
Skin Protection: Impermeable gloves and laboratory coat
Respiratory Protection: Dust mask if dust is generated
Hygiene Measures: Wash hands before breaks and after handling
Appearance: White to pale yellow crystalline powder
Odor: Odorless
Molecular Formula: C22H17ClN2
Molecular Weight: 344.8 g/mol
Melting Point: About 147-149°C
Water Solubility: Practically insoluble in water
Solubility (Other): Soluble in acetone, chloroform, and alcohol
pH: Not applicable
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Log Kow ~6.1
Boiling Point: Decomposes before boiling
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not chemically reactive under normal handling
Conditions to Avoid: Excess heat, light, moisture
Incompatible Materials: Strong oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrochloric acid, nitrogen oxides
Acute Toxicity (Oral): Low toxicity, LD50 in rats: 761 mg/kg
Skin Corrosion/Irritation: Mild skin irritant
Eye Damage/Irritation: May cause eye irritation
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Sensitization: No evidence of skin sensitization in animal studies
Long-term Effects: No significant health hazards with normal use
Ecotoxicity: Harmful to aquatic organisms at high concentrations
Persistence and Degradability: Not readily biodegradable
Bioaccumulative Potential: High potential due to log Kow value
Mobility in Soil: Low, binds strongly to soil and sediment
Other Adverse Effects: Avoid release to the environment
Waste Disposal Methods: Dispose of contents/container in accordance with local, regional, national, and international regulations
Incineration: Preferred method for disposal in accordance with applicable laws
Do Not: Discharge into drains, water courses, or onto the ground
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not regulated
Environmental Hazards: Not classed as a marine pollutant
Special Precautions: No special requirements for air, rail, road, or sea transport
US Regulations: Not considered hazardous under OSHA regulations
TSCA Inventory: Listed
SARA Title III: Not subject to reporting
FDA: Approved for topical antifungal use
EU Regulations: Listed in EINECS, not classified as a hazardous substance under CLP
Other Regulations: Observe all local and international regulations
