© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Ciprofloxacin Hydrochloride
Chemical Family: Fluoroquinolone antibiotic
CAS Number: 86393-32-0
Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride, Cipro HCl
Recommended Use: Pharmaceutical substance; antibacterial treatment for humans
Supplier Details: [Company Name, Address, Phone, Emergency Contact]
Classification: Harmful if swallowed, may cause irritation to respiratory tract and skin, may cause serious eye damage, possible adverse effects on reproduction based on animal studies
GHS Label Elements: Hazard pictograms (exclamation mark, health hazard)
Signal Word: Warning
Hazard Statements: H302: Harmful if swallowed; H315: Causes skin irritation; H319: Causes serious eye irritation; H335: May cause respiratory irritation
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; use protective gloves/eye protection
Health Effects: Headache, dizziness, gastrointestinal upset, allergic reactions, potential for tendon rupture based on long-term exposure
Ciprofloxacin Hydrochloride: 98-100% by weight
Other Components: None present in concentration >1%
Molecular Formula: C17H18FN3O3•HCl
Molecular Weight: 385.8 g/mol
Impurities and Stabilizing Additives: Not relevant at pharmaceutical grade
Inhalation: Remove to fresh air, seek medical attention if symptoms persist
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, obtain medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention immediately
Acute Symptoms and Effects: May cause nausea, diarrhea, abdominal pain, allergic skin reactions
Special Advice to Physicians: Symptomatic treatment as required, monitor for signs of allergic response
Suitable Extinguishing Media: Use water spray, foam, dry chemical or CO2
Specific Hazards: Combustion may generate toxic fumes containing fluorine, nitrogen oxides, and carbon monoxide
Fire Fighting Instructions: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes; prevent run-off from fire control from entering drains or watercourses
Explosion Data: Not known to be sensitive to mechanical impact or static discharge
Personal Precautions: Avoid dust generation; use personal protective equipment including gloves, mask, and eye protection
Environmental Precautions: Prevent entry into drains, surface water or soil; notify authorities in case of large spill
Methods for Cleanup: Sweep or vacuum without creating dust, place in suitable container for disposal; clean area with water
Decontamination: Wash spill area thoroughly with water and disinfectant if necessary
Handling: Handle in accordance with good laboratory hygiene and safety practice; avoid inhalation, contact with skin or eyes; use local exhaust ventilation if dust generated
Storage: Keep container tightly closed in a cool, dry, well-ventilated place; protect from light and moisture; store away from incompatible materials like strong acids, bases, oxidizers
Packaging Materials: Use original manufacturer’s container or suitably labeled containers
Exposure Limits: Occupational exposure limits not established for active ingredient; minimize exposure as standard GMP practice
Engineering Controls: Use local exhaust ventilation; keep dust levels as low as possible
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, laboratory coat; particulate respirator if dust present
Hygiene Measures: Wash hands thoroughly after handling; avoid eating, drinking, or smoking in work areas; remove contaminated clothing and clean before reuse
Appearance: White to slightly yellow crystalline powder
Odor: Odorless or faint characteristic odor
pH (1% solution): 3.5–5.0
Melting Point: 320 °C (decomposes)
Boiling Point: Not applicable
Flash Point: Not applicable
Solubility: Freely soluble in water; slightly soluble in methanol; practically insoluble in acetone and ethanol
Vapor Pressure: Not applicable
Density: 1.6–1.7 g/cm³
Partition Coefficient: logP 0.28 (octanol/water)
Other: Stable under recommended storage conditions
Chemical Stability: Stable under normal conditions of use and storage
Reactivity: Non-reactive under standard conditions
Hazardous Reactions: Can react with strong oxidizing agents
Decomposition Products: Thermal breakdown produces nitrogen oxides, hydrogen chloride, carbon monoxide, carbon dioxide, and fluorine compounds
Incompatibilities: Strong acids, strong bases, strong oxidizers
Acute Toxicity: LD50 (oral, rat): 5000 mg/kg
Skin Corrosion/Irritation: May cause irritation on prolonged/repeated contact
Serious Eye Damage/Irritation: Causes irritation
Respiratory Sensitization: Possible with high exposure to dust
Skin Sensitization: Not typical
Germ Cell Mutagenicity: Not classified as mutagenic based on available studies
Carcinogenicity: No evidence of carcinogenic potential in standard animal testing
Reproductive Toxicity: Adverse effects observed in animal studies; not fully established in humans
Specific Target Organ Toxicity: Prolonged exposure may affect the central nervous system, liver, and kidneys
Other Data: CNS effects like headache, dizziness reported in some users
Ecotoxicity: Harmful to aquatic life; LC50 (Fish, 96h): 85 mg/L; EC50 (Daphnia, 48h): 130 mg/L
Persistence and Degradability: Moderately persistent; not readily biodegradable
Bioaccumulative Potential: Low, based on log Pow
Mobility in Soil: Expected to have moderate mobility
Other Adverse Effects: May contribute to antibiotic resistance if released in large amounts to the environment
Waste Treatment Methods: Dispose by incineration in an approved facility; avoid discharge into sewers or natural waterways
Contaminated Packaging: Triple rinse and offer for recycling or reconditioning, or dispose as hazardous waste
Special Precautions: Follow local, regional, and national regulations for disposal
UN Number: Not regulated for transport as hazardous material
Proper Shipping Name: Not regulated
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not a marine pollutant
Special Precautions: Protect from physical damage, temperature extremes, moisture during transport
US Regulations: Listed in TSCA inventory; subject to pharmaceutical manufacturing regulations
EU Regulations: Registered under REACH for specified uses; subject to Directive 2001/83/EC for medicinal products
Labeling Requirements: Must follow guidelines set by OSHA Hazard Communication Standard and GHS
Other International Regulations: Meets requirements of Canada WHMIS, Australia SUSMP, and Japan CSCL as relevant
