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Product Name: Ciclopirox
Chemical Formula: C12H17NO2
CAS Number: 29342-05-0
Recommended Use: Antifungal agent used in topical medications
Supplier Details: Manufacturer names, addresses, and emergency phone numbers appear on packaging materials
Synonyms: 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
Use Restrictions: Industrial and healthcare settings, not for direct ingestion or eye contact
Emergency Phone: Refer to local or supplied package instructions
GHS Classification: Irritant, may cause skin and eye irritation
Pictogram: Exclamation mark (irritant symbol)
Signal Word: Warning
Hazard Statements: Causes moderate skin irritation, eye irritation, and may cause respiratory tract irritation upon inhalation of dust
Precautionary Statements: Wear protective gloves, avoid inhalation or contact with skin and eyes, wash hands thoroughly after handling
Symptoms of Exposure: Redness, discomfort, watering eyes, cough, headache
Route of Entry: Skin, inhalation, eye contact
Target Organs: Skin, eyes, respiratory tract
Other Dangers: Not known to be carcinogenic; check current literature for updates
Ciclopirox: 99% (active ingredient)
Impurities: Not more than 1%, specific chemical names withheld as trade secret
Inactive Ingredients: None stated in raw form; topical preparations may include carriers or alcohols
Exposure Limits: No established threshold limit value for pure substance; standard industrial hygiene recommended
Inhalation: Move person to fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Wash immediately with soap and water, remove contaminated clothing, consult physician if irritation continues
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, get medical help for continued irritation
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice immediately
Key Symptoms: Irritation of exposed tissues (skin, eyes, throat), possible mild gastrointestinal upset
Medical Attention: Always provide product label or MSDS to health professionals
Suitable Extinguishing Media: Dry powder, carbon dioxide, foam, water spray
Unsuitable Methods: High-pressure water streams may spread powder
Specific Hazards: Combustion produces carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment for Firefighters: Full protective suit, self-contained breathing apparatus
Special Precautions: Cool containers exposed to heat, avoid breathing vapors
Explosion Data: No explosive properties identified
Spill Procedures: Ventilate area, avoid dust formation, collect mechanically, transfer to labeled waste container
Personal Precautions: Use gloves, goggles, masks as needed to minimize skin and dust exposure
Small Spills: Sweep onto paper, dispose as chemical waste
Large Spills: Prevent entry to drains or watercourses, inform environmental authorities if contamination risk
Environmental Precautions: Avoid dispersal of material, cleanup promptly
Handling: Avoid dust generation, do not eat or drink during use, open containers carefully, minimize contact
Storage Conditions: Keep tightly sealed in original container, store cool and dry, protect from light and humidity
Incompatible Materials: Strong oxidizers, acids, alkalis
Storage Temperature: Preferably below 25°C
Security: Restrict access to trained personnel
Engineering Controls: Work with local exhaust, containment devices, and closed systems if powder is handled
Personal Protective Equipment: Nitrile latex gloves, safety goggles, laboratory coats
Respiratory Protection: Dust mask or respirator for dusty conditions
Hygiene Measures: Wash hands before eating, do not touch face or eyes, change contaminated clothing promptly
Environmental Controls: Prevent dust release, use in well-ventilated area
Appearance: White to off-white crystalline powder
Odor: Odorless or faint odor
Melting Point: 95-98°C
Boiling Point: Not established, decomposes before boiling
Solubility: Slightly soluble in water, soluble in organic solvents like ethanol and methanol
pH: Not applicable (solid)
Vapor Pressure: Not available
Density: Approximately 1.08 g/cm³
Partition Coefficient (log P): 2.59
Flash Point: Not available
Other Properties: Stable under normal conditions
Chemical Stability: Stable under recommended storage and handling
Reactivity: No dangerous reactions known with normal use
Conditions to Avoid: Exposure to strong light, heat, and moisture
Incompatible Materials: Strong acids, bases, oxidizers
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen compounds
Acute Toxicity: Oral LD50 in rats: over 2,000 mg/kg
Skin Corrosion/Irritation: Can cause moderate irritation with prolonged exposure
Serious Eye Damage/Irritation: Causes redness, watering, stinging on direct contact
Respiratory Sensitization: May lead to cough or throat discomfort if powder is inhaled
Ingestion Risks: Mild gastrointestinal irritation
Chronic Exposure: No evidence of mutagenicity or carcinogenicity in current studies
Additional Effects: Allergic skin reactions possible in sensitive individuals
Ecotoxicity: Possible hazard to aquatic life, avoid uncontrolled release to waterways
Persistence and Degradability: Poorly biodegradable in the environment
Bioaccumulation: Low potential based on partition coefficients
Mobility in Soil: May leach to some extent in moist conditions
Other Effects: Follow local environmental protection guidelines
Waste Disposal Methods: Dispose as hazardous chemical waste using local, regional, national regulations
Container Disposal: Decontaminate and send for recycling or disposal according to chemical compatibility
Unused Product: Return to manufacturer or licensed chemical disposal contractor
Precautions: Avoid contamination of soil, water, drains, and sewers
UN Number: Not assigned for small quantities or non-bulk industrial use
UN Proper Shipping Name: Not regulated for transport under most national and international regulations
Transport Hazard Class: No specific class
Packing Group: Not assigned
Environmental Hazards: Not considered marine pollutant, still keep tightly sealed and protected from damage
Special Precautions for User: Protect package from movement, heat, and moisture; handle according to workplace safety guidelines
Labeling Requirements: Complies with OSHA, EU, and similar safety information regulations for workplace labeling
Chemical Inventory Status: Listed in TSCA, EINECS/ELINCS, and most major chemical inventories
Safety Assessment: Not assigned significant hazard ratings; topical uses regulated as prescription medicine
Workplace Control: Employers should display MSDS and provide necessary training and protective equipment
Other Regulatory Effects: Updates appear as authorities release new hazard data or occupational limits
