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Product Name: Cholesterol
Chemical Name: Cholest-5-en-3β-ol
CAS Number: 57-88-5
Molecular Formula: C27H46O
Molecular Weight: 386.65 g/mol
Recommended Use: Laboratory reagent, pharmaceutical intermediate, or standard
Supplier Details: Name, address, and contact information available on request from issuing laboratory
Emergency Contact: Refer to local regulations and company emergency phone number
GHS Classification: Not classified as hazardous according to current GHS standards
Label Elements: No pictogram, signal word, or hazard statement required
Hazard Risk: May cause mild skin and eye irritation; inhalation of dust might cause respiratory irritation
Precautionary Statements: Avoid formation of dust. Use appropriate personal protective equipment. Handle in accordance with good laboratory practices.
Other Hazards: May pose a risk for water pollution if not disposed properly. Not considered flammable, explosive, or oxidizing.
Chemical: Cholesterol
Concentration: 98% or higher
Impurities: Minimal, typical impurities include trace sterols and moisture
Synonyms: 3β-Hydroxycholest-5-ene
EINECS Number: 200-353-2
FDA Status: Listed for pharmaceutical or nutritional use with restrictions on purity and application
Inhalation: Remove person to fresh air. If symptoms like breathing difficulty persist, seek medical care.
Skin Contact: Wash area with soap and water. Take off contaminated clothing. Seek attention if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes while holding eyelids open. Contact physician if discomfort continues.
Ingestion: Rinse mouth thoroughly. Never give anything by mouth to an unconscious person. Seek medical assistance for persistent symptoms.
Symptoms: May include rash, mild coughing, eye discomfort; serious effects from normal contact unlikely
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide
Specific Hazards: Burning releases carbon monoxide, carbon dioxide, possibly irritating fumes
Special Protective Equipment: Firefighters require NIOSH-approved self-contained breathing apparatus and protective clothing
Precautionary Measures: Avoid inhaling vapors or smoke generated by fire
Additional Info: Product may melt and flow in intense heat creating slip hazard
Personal Precautions: Avoid contact with skin, eyes, and clothing; prevent dust formation; ventilate area
Environmental Precautions: Prevent product from entering drains, watercourses, or soil
Containment & Cleaning: Sweep up spilled material without creating dust; collect in suitable container for disposal; wash spill area with water and mild detergent
Protective Equipment: Use gloves, goggles, and a dust mask if significant dust is generated
Handling: Use good industrial hygiene practices. Minimize formation of dust and aerosol. Avoid inhalation, ingestion, and direct contact with skin and eyes.
Storage Conditions: Keep container tightly closed in a well-ventilated, dry, and cool place. Store away from strong oxidizing agents or acids. Recommended storage temperature usually 2-8°C.
Other Advice: Use only with adequate ventilation and appropriate PPE. Wash thoroughly after handling. Label containers clearly.
Engineering Controls: Local exhaust ventilation or appropriate solution to keep airborne concentrations below recommended limits
Exposure Limits: Occupational exposure limit values not established for cholesterol
Personal Protective Equipment: Safety glasses or chemical splash goggles, protective gloves (nitrile or similar), lab coat, and dust mask
Hygiene Measures: Wash hands and face after handling; remove contaminated clothing immediately and wash before reuse
Appearance: White or pale yellow crystalline powder
Odor: Odorless
Melting Point: Approximately 148–150°C
Boiling Point: Not available (decomposes before boiling)
Solubility: Practically insoluble in water; soluble in ether, chloroform, and ethanol
Density: Approximately 1.05 g/cm³
Vapor Pressure: Not determined (negligible at ambient conditions)
Partition Coefficient (log Kow): Estimated 9.0
pH: Not applicable (solid)
Volatility: Low
Chemical Stability: Chemically stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, exposure to light, strong oxidizing agents, acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, potentially toxic fumes under fire or decomposition conditions
Incompatible Materials: Strong acids, strong bases, oxidizing materials
Polymerization: Product does not polymerize
Acute Toxicity: Low toxicity based on available data; comparable to other common sterols
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms of Exposure: Mild skin or eye irritation, coughing or discomfort with repeated dust exposure
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in humans or animals; long-term exposure effects not well documented
Sensitization: Not considered a skin or respiratory sensitizer
Other Data: Widely present in animal tissues, minor irritant at most occupational exposure levels
Ecotoxicity: Not considered acutely toxic to aquatic life based on available studies; insoluble in water so limited bioavailability
Persistence/Degradability: Naturally occurring substance, biodegradable through standard environmental processes
Bioaccumulative Potential: High log Kow suggests potential for bioaccumulation but limited transport due to low solubility
Mobility in Soil: Expected to be immobile because of low water solubility
Other Adverse Effects: No known significant environmental hazards under normal usage and disposal
Disposal Methods: Dispose of in accordance with local, regional, and national regulations; best handled at licensed chemical disposal facility
Contaminated Packaging: Triple rinse containers before disposal or recycling as required by waste handlers
Precautions: Do not discharge into surface water or sewer system; incineration preferred for large quantities
Waste Code: Not assigned a hazardous waste code but consult authorities based on region
UN Number: Not assigned; not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Proper Shipping Name: Not regulated for transport
Special Precautions: Ship in tightly sealed, labeled containers. Prevent contact with incompatible substances during transport.
Regulatory Listings: Listed on TSCA (USA), EINECS/ELINCS (EU), and other major inventories. Specific country regulation details available through supplier or safety officer.
Labelling Requirements: No hazard classification labeling required under GHS; workplace labeling with standard precautionary guidance recommended
SARA Title III: Not listed under hazardous substances reportable to US EPA
REACH Status: Exempt from registration as a naturally occurring substance unless chemically modified or used in quantities above regulatory thresholds
Other Regulations: Does not contain substances listed as controlled under international conventions; intended use may be subject to FDA, EMA, or local health authority requirements
