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Product Name: Chlorzoxazone
Chemical Formula: C7H4ClNO2
Synonyms: 5-Chloro-2-benzoxazolinone
Recommended Use: Muscle relaxant (pharmaceutical preparation)
CAS Number: 95-25-0
Supplier Details: Manufacturer information available on invoice or bulk packaging
Emergency Contact: Toxicology hotline or local poison control resources
UN Number: Not regulated for transport
Relevant Identified Uses: Suitable for laboratory and pharmaceutical industry use
GHS Classification: Acute toxicity (oral), category 4; Eye irritation, category 2A; Specific target organ toxicity (repeated exposure), category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes serious eye irritation; May cause damage to organs through prolonged or repeated exposure
Pictograms: Exclamation mark, Health hazard
Health Hazards: Possible effects on the liver, nervous system, and gastrointestinal tract
Precautionary Statements: Avoid ingestion, contact with eyes or prolonged exposure, use in well-ventilated areas
Substance Name: Chlorzoxazone
Purity: Generally exceeds 98% for pharmaceutical preparations
Impurities: Trace impurities may include chlorinated benzoic acids, benzoxazolinone isomers
Other Components: No hazardous excipients used in standard preparations
Inhalation: Move to fresh air, monitor respiratory symptoms, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash affected area with soap and water, consult a physician if irritation develops
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present, continue rinsing, seek medical attention
Ingestion: Rinse mouth, do not induce vomiting, call poison control or a physician immediately
Most Important Symptoms: Gastrointestinal upset, headache, dizziness, eye discomfort
Immediate Medical Attention: Required for significant ingestion or prolonged exposure
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Direct water jet may spread material
Specific Hazards: Combustion produces toxic fumes including nitrogen oxides, hydrogen chloride, phosgene
Protective Equipment: Wear self-contained breathing apparatus, chemical protective clothing
Firefighting Instructions: Control runoff to prevent environmental contamination, avoid inhalation of thermal decomposition products
Personal Precautions: Use protective gloves, goggles, avoid dust formation
Environmental Precautions: Prevent entry into sewers or waterways
Cleanup Methods: Sweep up spilled material, avoid creating dust, collect in suitable containers for disposal, ventilate area
Decontamination: Wash spill area with soap and water after removal
Handling: Use only in well-ventilated areas, avoid inhalation and direct contact, practice good industrial hygiene
Storage Conditions: Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers
Packaging: Keep container tightly closed and appropriately labeled
Special Handling Instructions: Avoid contact with skin, eyes, and clothing, wash hands thoroughly after handling
Occupational Exposure Limits: No established ACGIH or OSHA TLV, minimize exposure through engineering controls
Engineering Controls: Use fume hood or local exhaust ventilation
Personal Protective Equipment: Safety goggles, gloves resistant to chemicals, lab coat, respiratory protection if dust or fumes are generated
Hygiene Measures: Wash hands after use, do not eat, drink, or smoke in work areas
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: Not available in standard aqueous solution
Melting Point/Freezing Point: 185-189°C (365-372°F)
Boiling Point: Decomposes on heating, does not boil without degradation
Flash Point: Not established, likely to decompose below boiling
Evaporation Rate: Negligible
Flammability: Not classified as flammable
Upper/Lower Flammability Limit: Not available
Vapor Pressure: Practically non-volatile
Vapor Density: Not available
Relative Density: 1.4 – 1.6 g/cm³
Solubility: Slightly soluble in water, soluble in alcohol and acetone
Partition Coefficient (log Kow): 1.42
Auto-ignition Temperature: Not available
Decomposition Temperature: Decomposes on heating
Viscosity: Not relevant (solid at room temperature)
Chemical Stability: Stable under recommended storage conditions
Reactivity: No dangerous reactions known under normal storage and use
Conditions to Avoid: Excessive heat, open flames, high humidity
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: Hydrogen chloride, oxides of carbon and nitrogen, phosgene possible on combustion
Polymerization: Will not occur under normal handling
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Toxicity: Oral LD50 (rat): 720 mg/kg; may be toxic if swallowed in quantity
Skin Corrosion/Irritation: May cause mild irritation with prolonged or repeated contact
Serious Eye Damage/Irritation: Irritating to eyes
Mutagenicity: Some evidence in laboratory studies, significance for humans unclear
Carcinogenicity: Not listed as carcinogenic by IARC or NTP, long-term effects not fully evaluated
Reproductive Toxicity: Data not conclusive; consult specific regulations for risk management
Target Organ Effects: Liver, nervous system with prolonged exposure or large doses
Symptoms: Headache, nausea, dizziness, allergic-type skin reactions possible
Aquatic Toxicity: May be harmful to aquatic life, avoid discharge to natural waterways
Persistence and Degradability: Slow degradation; not readily biodegradable
Bioaccumulative Potential: Log Kow suggests moderate potential
Mobility in Soil: Low to moderate mobility expected
Other Adverse Effects: Avoid release; ecological data limited but concerns for long-term accumulation exist
Product Disposal: As hazardous chemical waste in accordance with local, regional, and national regulations
Packaging Disposal: Contaminated containers considered hazardous, require proper cleaning or disposal
Additional Guidance: Consult waste disposal authority for acceptable procedures; do not dispose in sink, sewer, or regular landfill
UN Number: Not classified as a hazardous substance for transport
Transport Hazard Class: Not regulated
Proper Shipping Name: Chlorzoxazone (for reference)
Packing Group: Not regulated
Environmental Hazards: Minimum but avoid release to environment
Special Precautions: Protect from humidity and extreme heat during transport
OSHA Hazard Communication: Listed; follow workplace hazard standards
TSCA Inventory: Listed
EU REACH Registration: Substance manufactured/imported above threshold requires registration
WHMIS Classification: Class D2B (toxic materials causing other effects)
SARA Title III Section 313: Subject to reporting in the United States
Other Relevant Regulations: Subject to prescription pharmaceutical controls in many regions; waste handling subject to local environmental laws
