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Chemical Name: Chlorquinaldol
Common Names: 5,7-dichloro-8-hydroxyquinoline, Diquinol
Molecular Formula: C9H5Cl2NO
CAS Number: 148-68-3
Intended Use: Pharmaceutical antiseptic, topical antimicrobial
Manufacturer Contact: Information must include address, phone, emergency contact for chemical provider or distributor
Product Code: Listed by supplier depending on batch
Recommended Use: Formulated for topical antimicrobial applications on skin and mucous membranes
Restriction: Strictly external use; avoid ingestion and inhalation
Globally Harmonized System Classification: Eye irritation (Category 2), Skin irritation (Category 2), Acute toxicity oral (Category 4)
Hazard Statements: Harmful if swallowed, causes irritation to eyes, skin, and mucosa
Pictograms: Exclamation mark, Health hazard symbol
Signal Word: Warning
Route of Exposure: Skin contact, eye contact, ingestion
Precautionary Statements: Avoid breathing dust or particles; rinse eyes and skin thoroughly after handling; wash hands before breaks and after handling compound
Symptoms of Overexposure: Burning, redness, headache, nausea, confusion following significant accidental ingestion
Component: Chlorquinaldol
Concentration: 98–100% (pharmaceutical grade)
Impurities: Trace organic solvents (as residuals from manufacturing), less than 0.5% unreacted precursors (specified by producer)
Additives / Stabilizers: None commonly added in raw chemical form
Form: Crystalline or powder
Eye Contact: Rinse immediately with plenty of clean, lukewarm water for at least 15 minutes; remove contact lenses if possible; seek medical help if irritation persists
Skin Contact: Wash with soap and running water for several minutes; remove contaminated clothing; medical attention recommended for persistent symptoms
Inhalation: Remove to fresh air; seek medical attention if respiratory irritation, headache, or nausea occur
Ingestion: Rinse mouth thoroughly with water; never induce vomiting; contact a poison control center or physician immediately
Most Important Symptoms: Persistent burning, discomfort; accidental ingestion can lead to nausea, abdominal cramping, possible neurological symptoms
Suitable Extinguishing Agents: Dry chemical, foam, carbon dioxide, water spray for larger fires
Unsuitable Media: Use water sparingly if powder is present to avoid chemical runoff
Protective Equipment for Firefighters: Self-contained breathing apparatus, full chemical-resistant clothing
Combustion Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide
Special Hazards: Fumes from heating or fire can irritate respiratory tract
Fire Precautions: Containers may explode from heat; move materials away if possible without risk
Precaution: Evacuate area, ventilate
Personal Protection: Wear gloves, goggles, lab coat or coveralls; respiratory protection if powder is airborne
Containment: Sweep up carefully without generating dust; collect in sealable, labeled containers
Clean-up Procedure: Wash residue area with soapy water; prevent spills from entering soil or waterways
Environmental Precaution: Prevent run-off to drains, surface water, or ground water
Safe Handling: Work in well-ventilated area; avoid producing or breathing dust; avoid skin and eye contact; use only with proper PPE
Storage: Store tightly closed in original container; keep in cool, dry place from light, incompatible substances (strong acids, oxidizers); keep away from food and animal feed
Hygiene Measures: Wash hands after handling; do not eat or drink in work area; clean up spills quickly
Other Advice: Use designated chemical storage cabinets if possible; isolate from strong reducing or oxidizing agents
Engineering Controls: Fume hood or local exhaust ventilation
Exposure Limits: No workplace exposure limit has been set in several jurisdictions, but minimize dust exposure
Respiratory Protection: Dust mask or particulate respirator if airborne powder present
Eye Protection: Safety glasses, chemical splash goggles
Skin Protection: Chemical-resistant gloves (nitrile, latex, neoprene); lab coat or apron
General Protection: Remove and launder contaminated clothing; avoid secondary contamination of surfaces
Appearance: Pale yellow to white crystalline powder
Odor: Odorless or faint, phenolic
Molecular Weight: 216.05 g/mol
Melting Point: 168–172 °C
Boiling Point: Approximately 400 °C (decomposes)
Solubility: Very slightly soluble in water; soluble in alcohols, chloroform, acetone, ether
pH: Not measurable directly in solid state; slightly acidic in dissolved form
Vapor Pressure: Negligible at room temperature
Partition Coefficient (Log Kow): Approximately 2.7 (estimated)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive under normal conditions
Hazardous Reactions: Contact with strong oxidizers, acids, reducing agents can trigger decomposition
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide
Incompatible Materials: Strong acids, oxidizers, alkali metals
Conditions to Avoid: High heat, exposure to light, ignition sources
Acute Toxicity: LD50 (rat, oral) ~350 mg/kg; harmful if swallowed
Chronic Effects: Prolonged exposure can cause skin sensitization, neurotoxic symptoms, or allergic reaction
Carcinogenicity: No recognized carcinogenic risk according to IARC, OSHA, NTP data
Mutagenicity: No standard evidence for genotoxicity; no mutagenic data in typical safety studies
Other Health Effects: Eye, skin, and mucous irritation; severe overdose may cause confusion, tremors, incoordination
Medical Monitoring: Medical supervision advised for workers with repeated handling or accidental exposure
Aquatic Toxicity: Toxic to aquatic organisms at high concentrations; may cause long-term adverse effects in aquatic environment
Persistence and Degradability: Moderately persistent; limited biodegradability reported
Bioaccumulative Potential: Moderate based on Log Kow; potential to bioaccumulate in aquatic species
Mobility in Soil: Low water solubility results in low mobility; can bind to soil or sediment
Other: Prevent large-scale contamination of waterways; report spills to appropriate agencies
Waste Treatment: Dispose of contents/container following national and local regulations
Method: Incineration at licensed chemical waste facility preferred; avoid landfill disposal
Precautions: Do not allow to enter sewers, drains, or natural waterways
Container Disposal: Triple-rinse; puncture and send for proper hazardous waste management
Recycling: Not practical for typical discarded quantities
UN Number: Not assigned for this specific chemical
Proper Shipping Name: Not classified as dangerous for transport by most regulatory agencies
Transport Hazard Class: Not regulated under ADR/RID, IMDG, or IATA in small quantities
Packing Group: Not applicable
Marine Pollutant: Not designated, although environmental harm possible if released
Special Precautions: Secure containers to avoid movement or breakage during carriage
United States: Not listed as hazardous substance under CERCLA or SARA; not controlled by TSCA
Europe: Not subject to classification under REACH Annex XVII; advisory labeling may apply
Other Countries: Conforms to local pharmaceutical and chemical statutes
Inventory Listings: EINECS/ELINCS (EU), AICS (Australia), DSL/NDSL (Canada), PICCS (Philippines)
Label Elements: Required warnings for irritation, harmful if ingested, avoid skin and eye contact
Workplace Guidance: Follow local chemical hygiene and safety rules for handling hazardous substances
