© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Chlorobutanol Hemihydrate
Chemical Name: 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
CAS Number: 107-89-1
Molecular Formula: C4H7Cl3O · 0.5H2O
Recommended Use: Pharmaceutical preservative, laboratory reagent
Supplier Details: Manufacturer or distributor information, including phone emergency contact
Synonyms: Chlorbutol Hemihydrate, Trichlorobutanol Hemihydrate
Emergency Phone: CHEMTREC or local poison control
Classification: Acute toxicity (oral, dermal, inhalation), skin and eye irritant
Hazard Statements: Toxic if swallowed, inhaled, or in contact with skin; causes skin and serious eye irritation
Pictograms: Skull and crossbones, exclamation mark
Signal Word: Danger
Precautionary Statements: Avoid breathing dust and vapors, wear protective gloves and eye/face protection, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, keep out of reach of children
Chemical Name: Chlorobutanol Hemihydrate
Concentration: 98-100%
CAS Number: 107-89-1
Impurities/Other Components: May contain trace moisture from hemihydrate form, no hazardous stabilizers or additives noted
Inhalation: Move affected person to fresh air, provide artificial respiration if breathing stops, get medical support promptly
Skin Contact: Remove contaminated clothing, wash skin with plenty of soap and water, seek medical attention if rash or irritation occurs
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses, continue rinsing; obtain medical assistance
Ingestion: Rinse mouth, do not induce vomiting, call poison center or a doctor, never give anything by mouth to an unconscious person
Most Important Symptoms: Severe irritation, coughing, headaches, risk of CNS depression, drowsiness, confusion in severe cases
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray
Specific Hazards: Releases toxic fumes under fire conditions, such as hydrogen chloride, phosgene, and carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Firefighting Instructions: Avoid inhalation of fumes, cool exposed containers with water spray, evacuate area if necessary, control runoff to prevent entry into waterways
Personal Precautions: Use personal protective equipment, ensure adequate ventilation, avoid dust formation and inhalation
Environmental Precautions: Prevent further leakage or spillage; avoid discharge into drains, surface water, and soil
Spill Cleanup Methods: Scoop up and place in marked chemical-waste containers, clean spill site immediately with detergent, ventilate area, dispose of contaminated materials as hazardous waste
Handling: Avoid breathing dust or vapor, avoid contact with skin and eyes, wash hands thoroughly after use, use in approved chemical fume hood, maintain good industrial hygiene practices
Storage Conditions: Store in a tightly sealed container, keep in cool, dry, well-ventilated place away from incompatible substances such as oxidizers; protect from moisture
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents
Exposure Limits: No established OSHA/TLV exposure limits, minimize exposure as a precaution
Engineering Controls: Use local exhaust ventilation, process enclosures; handle in chemical fume hood
Personal Protection: Wear chemical-resistant gloves (nitrile preferred), protective lab coat or apron, safety goggles, and, if risk of dust, a NIOSH-approved respirator
Hygiene Measures: Contaminated clothing should be removed and washed, do not eat, drink, or smoke while handling
Physical state: Solid
Appearance: White crystalline powder
Odor: Mild camphor-like odor
Molecular Weight: 197.48 g/mol (anhydrous)
pH (1% solution): About 5.0-7.0
Melting Point: 78-81°C
Boiling Point: Decomposes
Solubility: Slightly soluble in water, soluble in alcohol and ether
Vapor Pressure: Not significant at ambient conditions
Density: 1.5–1.6 g/cm³
Partition Coefficient: log Kow 1.52
Flash Point: Not applicable (solid)
Stability: Stable under normal handling and storage conditions
Conditions to Avoid: Excess heat, moisture, light, incompatible materials
Hazardous Reactions: Reacts with strong oxidizers, acids, and bases with potential for hazardous byproducts
Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Acute Toxicity: Oral LD50 (rat): 200-400 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chronic Effects: CNS effects, possible liver and kidney damage with prolonged exposure
Irritation: Causes skin and serious eye irritation
Sensitization: Not classified as skin sensitizer based on current data
Carcinogenicity: Not listed by NTP, IARC, or OSHA
Reproductive Effects: No data reported
Symptoms: Drowsiness, confusion, nausea, local skin/eye inflammation
Aquatic Toxicity: May be harmful to aquatic life, data limited
Persistence and Degradability: Not readily biodegradable in natural environments
Potential Bioaccumulation: Low bioaccumulation predicted based on log Kow
Mobility: Low to moderate movement in soil, can contaminate groundwater if released in large quantities
Other Effects: Avoid uncontrolled release, follow all environmental protection codes
Disposal Method: Dispose of chemical waste in accordance with local, regional, and national regulations by a licensed hazardous waste contractor
Container Disposal: Triple rinse containers, puncture or crush and manage as hazardous waste
Precautions: Do not release to sewer or environment, incinerate in chemical incinerator equipped with scrubber
UN Number: Not assigned for pure chemical; consult local regulations
Transport Hazard Class: Not regulated under US DOT if in small quantities; confirm with shipping authority
Packing Group: Not classified
Labels: Not required for non-bulk shipment under current regulations
Transport Precautions: Package securely, shield from heat and moisture, avoid damage or leaks in transit
OSHA: Listed hazardous chemical, subject to worker right-to-know requirements
TSCA: Listed
SARA Title III: Not listed as a reportable quantity or extremely hazardous substance
California Prop 65: Not listed
EU Regulations: Classified as hazardous, requires CLP pictograms and caution
Other Regulations: Review country-specific health and chemical safety regulations prior to import, handling, or disposal
Workplace Control: Maintain workplace exposure records as required by law, ensure employee training for safe handling
