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Product Name: Cefquinome Sulfate
Chemical Formula: C24H24N6O5S2·H2SO4
Synonyms: 7-[2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[(aminomethyl) pyrrolidinio] methyl-3-cephem-4-carboxylate sulfate
CAS Number: 118443-89-3
Recommended Use: Veterinary pharmaceutical, antibiotic
Supplier Details: Active pharmaceutical ingredient producer or local distributor, addresses and phone numbers should be available from the supply chain documentation
Emergency Contact: National Poison Center or local health authority, emergency numbers available on local MSDS registry
GHS Classification: Acute toxicity (oral, inhalation, dermal), skin sensitizer, eye irritant
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause allergic skin reaction
Precautionary Statements: Avoid breathing dust or fumes, wash exposed area thoroughly, wear proper protective equipment, do not eat, drink, or smoke during handling
Label Elements: Exclamation mark, health hazard pictogram
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Environmental Impact: May pose risk to aquatic life
Active Ingredient: Cefquinome Sulfate, >98% purity
Impurities: Not specified for routine industrial batches; consult batch-specific documentation
Inactive Components: Trace degradants depending on storage age
Molecular Structure: Cephalosporin core with thiazole and pyrrolidinio side chains
Formula Weight: 612.7 (without sulfate)
Relevant Exposure Limits: Not established for occupational settings; treat as a sensitizer
Inhalation: Move individual to fresh air, monitor breathing, seek medical attention for persistent discomfort
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, seek medical advice if irritation develops
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, lift eyelids to ensure removal, obtain medical attention quickly
Ingestion: Rinse mouth, do not induce vomiting unless directed, get prompt medical care
Symptoms: Allergic reactions, rash, respiratory discomfort, eye redness
Advice for Responders: Avoid direct contact, use PPE including gloves, mask, and goggles
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Unsuitable Media: No specific restrictions, as the compound does not react violently with common extinguishing materials
Combustion Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Fire Hazards: Powder may become airborne and ignite under certain conditions if dust accumulates, although not highly flammable
Special Equipment: Self-contained breathing apparatus, full protective suit, avoid smoke inhalation
Precautions: Prevent runoff from contaminating waterways
Personal Protection: Wear gloves, goggles, dust mask or respirator, disposable gown
Spill Management: Avoid creating dust, contain material, use vacuum system or dampen to clean up
Clean-Up Procedures: Collect in container for disposal, wash area with water, avoid run-off into drains
Environmental Precautions: Prevent from entering water sources or soil
Notification: Notify affected personnel and, for large spills, local authorities
Disposal of Waste: Place waste in labeled, sealed containers for incineration or specialist handling
Handling: Use in well-ventilated areas, avoid dust creation, wear personal protective gear, keep containers tightly closed when not in use
Storage Conditions: Store in original packaging in cool, dry place, protect from light, do not freeze, separate from food and drinks, keep away from incompatible chemicals
Incompatibilities: Strong oxidizing agents, acids/bases
Hygiene Measures: Wash hands before eating or drinking, do not bring contaminated items into common areas
Engineering Controls: Local exhaust ventilation, process enclosures to minimize airborne dust
Exposure Limits: Not established by OSHA or ACGIH, handle as potential allergen
Respiratory Protection: NIOSH-approved respirator in absence of adequate ventilation
Skin Protection: Nitrile or latex gloves
Eye Protection: Chemical safety goggles or face shield
Body Protection: Lab coat or chemical-resistant apron
Hygiene: Wash hands thoroughly, avoid eating, drinking, or smoking during handling
Appearance: White to off-white crystalline powder
Odor: Faint, medicinal, not distinctive
pH (1% solution): 3.5-6.0
Melting Point: Decomposes above 200°C, does not exhibit a sharp melting point
Solubility: Freely soluble in water, slightly soluble in methanol, practically insoluble in chloroform and ether
Density: Not readily available, refer to supplier sheet for laboratory density
Vapor Pressure: Negligible at room temperature
Stability in Solution: Sensitive to heat, humidity, and light over prolonged periods
Chemical Stability: Stable under recommended storage conditions, decomposes with heat or strong light
Reactivity: Not highly reactive with common laboratory or industrial reagents
Decomposition Products: Produces toxic gases (sulfur oxides, nitrogen oxides) at high temperatures
Incompatible Materials: Strong oxidizers, acids and bases accelerate degradation
Hazardous Reactions: None reported under recommended conditions
Acute Toxicity: Data on mammalian LD50 not widely available, animal studies suggest moderate toxicity
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Symptoms: Allergic skin reactions, rash, hives, respiratory discomfort, eye irritation
Sensitization: Known skin sensitizer, possible cross-reactivity with other beta-lactams
Chronic Exposure: Repeated contact may cause dermatitis, rare systemic effects reported
Carcinogenicity: No long-term studies suggest cancer risk, not listed as a carcinogen by IARC, NTP, or OSHA
Mutagenicity: Negative in standard bacterial assays, limited data
Reproductive Effects: Not fully studied, some precaution advised for pregnant handlers
Aquatic Toxicity: Moderate risk to aquatic organisms, limited by product use volumes
Bioaccumulation: Does not bioaccumulate significantly according to available studies
Degradation: Breaks down under environmental conditions within weeks, but breakdown products may persist
Mobility in Soil: Mobile in water but binds to some extent with soil organics
Effects on Microorganisms: Can impact microbial life in wastewater
Environmental Precautions: Avoid release to environment or water systems, treat as pharmaceutical waste
Recommended Disposal: Incinerate in accordance with local regulations, certified hazardous waste processor
Container Disposal: Rinse well if plastic, then dispose per chemical waste protocols
Environmental Impact: Prefer destruction over landfill
Legal Requirements: Comply with country, state, and local hazardous waste laws
Special Instructions: Document quantities, transfer only using secure and labeled containment
UN Number: Not classified as dangerous by transport regulations
Transport Hazard Class: Not required
Packing Group: No restrictions
Environmental Hazards: Not a marine pollutant in normal shipment quantities
Labeling: Standard chemical labeling for laboratory chemicals
Special Precautions: Avoid damage to containers, protect from light and moisture during transit
EU Classification: Not classified under CLP for retail, categorized as veterinary API
US Federal Regulations: Not listed as hazardous under SARA, TSCA, or CERCLA
WHMIS: Not classified as controlled product
REACH Status: Subject to registration for manufacturing or import in the EU
FDA Status: Approved for veterinary use only
Other Regulations: Handle according to national veterinarian drug legislation, personal protection guidelines apply across all regions
