Product Name: Cefpirome Sulfate
Chemical Formula: C22H22N6O5S2·H2SO4
CAS Number: 104376-79-6
Intended Use: Pharmaceutical raw material, research, and laboratory settings
Manufacturer Identifier: Not specified (refer to product supplier)
Emergency Telephone Number: Available through local regulations or institutional protocol
Hazard Classification: Harmful if swallowed, irritating to eyes and respiratory system, potential skin sensitizer
Route of Entry: Inhalation, ingestion, skin, and eye contact
Signal Word: Warning
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
GHS Pictograms: Exclamation mark
Hazard Statements: Causes mild skin irritation, serious eye irritation, may cause allergic reaction in sensitized individuals
Active Ingredient: Cefpirome Sulfate
Synonyms: Cefpirome sulfate hemihydrate
Purity: ≥98% by HPLC
Impurities: Typical pharmaceutical-grade impurities below 1%
Excipient: None present in pure raw material form
Structurally Related Compounds: None noted in typical product
Inhalation: Remove exposed individual from area to fresh air, provide oxygen if breathing is difficult, seek medical attention for any persistent symptoms
Skin Contact: Wash exposed skin thoroughly with soap and water, remove contaminated clothing and seek medical advice if irritation persists
Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes, keep eyelids open, seek prompt medical attention
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek immediate medical care
General Advice: Show physician this sheet and packaging label when seeking advice
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, foam
Special Protective Equipment: Fire fighters require self-contained breathing apparatus and full protective gear
Unusual Fire or Explosion Hazards: Combustion may produce toxic and irritating fumes including oxides of nitrogen and sulfur
Thermal Decomposition Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Specific Hazards: Dust from product can form explosive mixtures in air
Personal Precautions: Avoid inhalation, contact with skin or eyes, ventilate area, evacuate unnecessary personnel
Spill Cleanup Methods: Sweep up spilled material carefully and place in suitable container for disposal, avoid raising dust
Environmental Precautions: Prevent further spillage or leakage, avoid discharge into drains and surface water
Protective Equipment: Use PPE including gloves, goggles, and a dust mask or respirator
Handling: Avoid generating dust, handle in well-ventilated spaces, wear suitable personal protection, wash hands thoroughly after handling
Storage Conditions: Keep container tightly closed, store in original packaging
Storage Temperature: Store at 2–8°C (refrigerated)
Incompatibilities: Strong acids, bases, and oxidizing agents
Safe Handling Advice: Avoid unnecessary exposure, keep out of reach of minors
Exposure Limit Values: No occupational exposure limits set by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize exposure
Personal Protective Equipment: Laboratory coat, chemical-resistant gloves, safety goggles, and appropriate respirator
General Hygiene Measures: Keep work clothes separate, wash hands before breaks and after work, avoid eating, drinking, or smoking in the work area
Appearance: White to off-white powder
Odor: Odorless
Melting Point: 210–214°C (decomposes)
pH (1% solution): 3.0–5.0
Solubility: Freely soluble in water
Flash Point: Not applicable
Vapor Pressure: Negligible at room temperature
Density: Not established
Partition Coefficient: Not measured
Other Data: Stable under recommended conditions
Chemical Stability: Stable when stored at recommended temperatures
Hazardous Reactions: No dangerous reactions known under normal conditions
Materials to Avoid: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: May release toxic fumes of sulfur and nitrogen oxides on decomposition
Polymerization: Product does not undergo hazardous polymerization
Acute Toxicity: Oral LD50 (rat): >2000 mg/kg
Skin Corrosion/Irritation: Mild irritant in animal models
Serious Eye Damage/Irritation: Moderate irritant
Respiratory or Skin Sensitization: Potential skin sensitizer in susceptible persons
Germ Cell Mutagenicity: No mutagenic effects observed in standard bacterial tests
Carcinogenicity: Not classified as carcinogenic
Reproductive Toxicity: No evidence from available data of reproductive toxicity
Long-Term Effects: Repeated exposure may cause allergic reactions in sensitized individuals
Medical Conditions Aggravated: Allergies to cephalosporins and penicillins, history of asthma or eczema
Ecotoxicity: Low acute toxicity to aquatic life, but effects on aquatic microorganisms possible
Mobility in Soil: Limited data, expected to be minimally mobile
Persistence and Degradability: Slowly biodegradable under environmental conditions
Bioaccumulation Potential: Unlikely to bioaccumulate
Additional Information: Avoid release into environment, toxic to aquatic organisms through life cycle
Waste Treatment Methods: Dispose of material through authorized chemical waste contractor
Contaminated Packaging: Rinse thoroughly before disposal or incinerate
Waste Code: Not established for this substance
Precautions: Do not discharge to sewage or surface water, follow all local regulations
Additional Advice: Notify appropriate agencies in case of large spill or contamination
UN Number: Not regulated under IATA, ADR, IMDG
Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not a marine pollutant
Special Precautions: Transport in secure, sealed, and labeled containers
Labelling under GHS: Exclamation mark hazard symbol, warning for skin/eye irritation and allergenicity
TSCA Status: Not listed
EINECS/ELINCS Status: Not listed
FDA/EMA: Subject to prescription-only and controlled handling under pharmaceutical laws
Workplace Safety: Covered by occupational health laws requiring PPE usage and risk assessment documentation
Other Regulatory Data: Product-specific regulations may apply in national or regional jurisdictions based on intended use