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Product Name: Cefoxitin Acid
Chemical Family: Cephalosporin antibiotics
Synonyms: Cefoxitin base, Cefoxitin free acid
CAS Number: 35662-16-7
Recommended Use: Research, synthesis of pharmaceuticals
Manufacturer: Pharmaceutical suppliers, chemical laboratory sources
Contact Information: Refer to the supplier’s emergency contact number and address provided on the product label.
Emergency Phone Number: Refer to local poison control center or emergency services.
Classification: Eye irritant, skin sensitizer, possible respiratory irritant, potentially harmful if swallowed
Signal Word: Warning
Hazard Statements: May cause allergic skin reaction, may cause respiratory irritation, causes serious eye irritation, harmful if inhaled or swallowed
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing dust or fumes, wash hands thoroughly after handling, avoid release to environment
Pictograms: Health hazard, exclamation mark
Chemical Name: Cefoxitin Acid
Concentration: Pure substance, typically over 95%
Impurities: May contain trace levels of related cephalosporin compounds or synthesis byproducts
Molecular Formula: C16H17N3O7S2
Molecular Weight: 427.45 g/mol
Inhalation: Move individual to fresh air, provide oxygen if breathing becomes difficult, seek medical attention if symptoms develop
Skin Contact: Wash gently with soap and water, remove contaminated clothing, consult physician for persistent irritation
Eye Contact: Rinse immediately with clean water for at least 15 minutes, hold eyelids apart, obtain medical attention immediately
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical advice, show MSDS or product label to healthcare professional
Most Important Symptoms: Allergic reactions, skin rash, respiratory discomfort, eye redness or tearing
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Extinguishing Media: Direct water jet for large fires, as splattering can occur
Hazardous Combustion Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Special Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Special Procedures: Remove all sources of ignition, prevent runoff from entering drains, keep containers cool with water spray
Personal Precautions: Evacuate area, wear appropriate protective equipment including respirator, gloves, goggles
Environmental Precautions: Prevent entry into soil, waterways, storm drains
Methods for Cleanup: Clean up mechanically, avoid raising dust, transfer to properly labeled waste container, ventilate area, wipe residue with damp cloth
Decontamination: Wash all surfaces and equipment thoroughly after material removal
Precautions for Safe Handling: Handle only in well-ventilated areas, use local exhaust if dust or vapor generation likely, avoid contact with skin, eyes, and clothing, do not breathe dust
Storage Conditions: Store in tightly-closed container, keep away from incompatible substances like strong oxidizing agents, protect from moisture and strong light, store at room temperature or as directed by supplier
Special Handling Advice: Use only with dedicated equipment, clean tools and surfaces before and after use, keep out of reach of unauthorized personnel
Engineering Controls: Work in a chemical fume hood, use local exhaust ventilation and keep workplaces clean
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or neoprene), laboratory coat or gown, eye protection with side shields, dust respirator if insufficient ventilation
Exposure Limits: No established occupational exposure limits; minimize exposure as much as possible
Environmental Controls: Avoid release into the environment, use containment and spill trays, wash down all surfaces after handling
Appearance: White to off-white powder
Odor: Odorless or faint medicinal smell
pH: Neutral to slightly acidic aqueous suspension
Melting Point/Range: 170–180°C (decomposition may occur before melting)
Boiling Point: Decomposes
Solubility: Slightly soluble in water, soluble in organic solvents like methanol or dimethyl sulfoxide
Vapor Pressure: Not applicable (non-volatile)
Density: Not determined
Partition Coefficient (log Kow): Not available
Other Data: Sensitive to light, hydrolysis possible in aqueous solutions, stable under recommended storage
Chemical Stability: Stable under normal temperatures and recommended storage conditions, labile to moisture and light
Reactivity: Can hydrolyze in presence of acids or bases, avoid strong oxidizers and reducers
Conditions to Avoid: High temperatures, humidity, exposure to direct sunlight, incompatible chemicals
Hazardous Decomposition Products: Decomposition may release toxic gases like NOx, SOx, and CO
Polymerization: Does not occur
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin, LD50 (oral/rat): not specifically defined for cefoxitin acid but similar cephalosporins show moderate toxicity
Chronic Effects: Prolonged exposure may cause allergic sensitization or skin reactions, repeated exposure can trigger occupational asthma and hypersensitivity
Route of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Allergic rash, difficulty breathing, eye redness, gastrointestinal disturbances
Target Organs: Immune system, respiratory system, skin
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Mutagenicity: No mutagenicity observed in standard bacterial assays
Reproductive Toxicity: Data insufficient, avoid exposure for pregnant or breastfeeding women
Ecotoxicity: Cephalosporins can disrupt aquatic microorganisms, low level toxic to aquatic invertebrates and algae
Persistence and Degradability: May display partial biodegradation, hydrolysis possible in presence of water and light
Bioaccumulation Potential: Low, due to poor lipid solubility
Mobility in Soil: Moderately mobile, dependent on soil pH and organic matter
Other Adverse Effects: Nervous system effects possible in higher organisms if released in excess to surface waters
Waste Disposal Method: Dispose by incineration in accordance with local, regional, and national regulations, do not dispose in landfill or municipal drains
Contaminated Packaging: Triple rinse and dispose of as hazardous chemical waste
Special Precautions: Use authorized chemical disposal contractor, document and record all hazardous waste movement, avoid environmental contamination
UN Number: Not regulated by ADR/RID/IMDG/IATA for transport
Proper Shipping Name: Cefoxitin Acid, chemical for laboratory research
Hazard Class: Not classified as dangerous for transport
Packing Group: Not applicable
Special Precautions: Avoid breakage during transit, ensure secure and proper labeling on containers
Transport in Bulk: Not intended for bulk transport
Regulatory Status: Subject to regulation as a pharmaceutical raw material, not listed on OSHA hazard chemicals, not regulated as an environmental toxin
SARA Title III Information: Not subject to reporting under SARA 313
TSCA: Not listed for non-clinical use
REACH Registration: Not registered as a stand-alone substance in the EU
WHMIS Classification: Health hazard
Other Regulations: Follow workplace safety directives for handling antibiotics and hazardous chemicals, maintain records of use and exposure, observe national and international chemical safety requirements, check local environmental or occupational restrictions before use
