© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Carboxin
Chemical Formula: C12H13NO2S
CAS Number: 5234-68-4
Synonyms: 5,6-Dihydro-2-methyl-1,4-oxathiin-3-carboxanilide
Recommended Use: Fungicide for seed treatment
Supplier Details: Global agricultural chemical suppliers, contact numbers, emergency helpline, and mailing address provided on commercial documentation.
Emergency Contact: National Poison Control Center, local fire departments, and hazardous chemical response teams.
Hazard Classification: Specific target organ toxicity—repeated exposure (oral, dermal); aquatic chronic toxicity
Pictogram: Health hazard, environment
Signal Word: Warning
Hazard Statements: Toxic if swallowed; causes mild skin irritation; suspected of causing damage to liver and kidneys through prolonged exposures; highly toxic to aquatic life with long lasting effects
Precautionary Statements: Do not eat, drink or smoke during use; avoid release to the environment; wear appropriate protective equipment on job sites.
Routes of Exposure: Inhalation, ingestion, dermal contact, ocular contact
Active Ingredient: Carboxin (98.0 – 99.0%)
Impurities: 1,4-Oxathiin compounds (<1%), proprietary surfactants (<1%)
Chemical Family: Anilide fungicides
Other Additives: Inert dust suppressants and wetting agents (<2%)
Exposure Limits: Occupational exposure limits not established for most ingredients.
Inhalation: Remove affected person to fresh air, monitor for symptoms like coughing or dizziness, and seek medical help if symptoms remain.
Eye Contact: Immediately rinse with clear running water for at least fifteen minutes, gently lifting the eyelids. Remove contact lenses and continue flushing if necessary. Obtain prompt medical attention.
Skin Contact: Remove all contaminated clothing. Wash exposed skin thoroughly with soap and plenty of water. If skin irritation or redness persists, consult medical personnel.
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical authority. Never give anything by mouth if the person is unconscious.
Medical Notes: Treat symptomatically; physicians should observe possible effects on the nervous system, liver, and renal function.
Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray suited to surrounding materials.
Unsuitable Media: Direct water jets can cause spreading, avoid if possible.
Specific Hazards: Toxic gases like nitrogen oxides, sulfur oxides, and unidentified organic compounds may form in fire.
Protective Equipment for Firefighters: Full protective suit, positive pressure self-contained breathing apparatus.
Thermal Decomposition: Decomposition products can irritate mucous membranes and respiratory tract.
Personal Protection: Wear impermeable gloves, goggles or face shield, chemical-resistant protective clothing and boots. Avoid skin or eye contact and prevent inhaling dust.
Environmental Precautions: Prevent further leakage or spillage if safe; contain spilled material to avoid contamination of soil and water sources.
Cleanup Methods: Use non-sparking tools. Sweep up without raising dust. Collect in suitable containers for proper disposal. Clean area with detergent and copious water.
Precautions for Emergency Responders: Avoid inhalation and contact during decontamination operations.
Safe Handling Practices: Use in well-ventilated areas. Avoid direct contact with formulation and dust. Do not eat, drink, or smoke during handling.
Conditions for Safe Storage: Keep tightly closed in original packaging. Store in a cool, dry, locked place away from direct sunlight or ignition sources.
Incompatibilities: Avoid storage with food, beverages, animal feeds, acids, and oxidizing agents.
Product Transfer: Equipment and containers should not be used for other chemicals, to avoid cross-contamination.
Engineering Controls: Local exhaust, mechanical ventilation, or fume hoods recommended in confined areas.
Respiratory Protection: Approved particulate respirator when dust or aerosolization is possible.
Skin and Body Protection: Impermeable gloves, long-sleeved protective coveralls, and safety boots.
Eye Protection: Chemical splash goggles or full-face shield.
Workplace Hygiene: Wash thoroughly after handling; remove contaminated clothing before entering eating and rest areas.
Appearance: White to pale yellow crystalline solid
Odor: Faint, characteristic
Odor Threshold: Not established
Melting Point: 92–95°C
Boiling Point: Not applicable for solid formulation
Solubility: Slightly soluble in water (<150 mg/L at 20°C), soluble in organic solvents such as acetone
Vapor Pressure: Very low at room temperature
Density: 1.24–1.26 g/cm3
pH (1% solution): 5.5–7.5
Partition Coefficient (log Kow): 2.87
Chemical Stability: Stable under regular storage and handling conditions.
Reactivity: No hazardous polymerization expected.
Conditions to Avoid: Excessive heat, moisture, direct sunlight, open flames, strong oxidizers.
Decomposition Products: Combustion or decomposition produces toxic fumes including carbon monoxide, sulfur oxides, nitrogen oxides, and possibly unidentified organic compounds.
Acute Toxicity – Oral: LD50 (rat): 3,800 mg/kg
Acute Toxicity – Dermal: LD50 (rabbit): ≥2,000 mg/kg
Eye Irritation: Moderate to severe irritant (rabbit studies)
Skin Sensitization: Mild irritant; not a sensitizer in animal testing
Chronic Toxicity: Target organ effects reported for kidney and liver upon repeated oral exposures in mammals
Carcinogenicity: Not listed as carcinogenic by OSHA, IARC, ACGIH, or NTP
Mutagenicity: Negative in standard mutagenicity assays such as Ames test
Symptoms of Exposure: Nausea, headache, skin or eye redness, respiratory discomfort observed in excessive accidental exposures
Ecotoxicity to Fish: Very toxic to aquatic organisms; LC50 (rainbow trout, 96h): 2.9 mg/L
Aquatic Invertebrates: High toxicity; Daphnia magna EC50 (48h): 4.3 mg/L
Aquatic Plants: Inhibits growth, but specific EC50 data limited
Persistence and Degradability: Moderately persistent in soil, half-life 60–100 days depending on environmental conditions, slow degradation in aquatic habitats
Bioaccumulation: Potential for accumulation in aquatic organisms suggested by log Kow value
Mobility: Low to moderate mobility expected in soil; leaching into groundwater a possibility in sandy or permeable soils
Other Adverse Effects: Not expected to significantly impact atmospheric ozone or contribute to photochemical smog
Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, according to local, regional, and national regulations.
Container Disposal: Triple rinse containers, puncture, and send to approved landfill or incineration. Do not reuse empty packaging.
Environmental Precautions: Do not contaminate surface waters or drains with product or used containers. Prevent entry into sewage systems.
Additional Advice: Coordinate with local environmental authorities for disposal protocols matching agricultural chemical regulations.
UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Carboxin)
Transport Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Environmentally hazardous substance mark required on all vehicles and cargo containing Carboxin.
Special Transport Precautions: Keep away from food and feedstuff. Store away from direct heat or incompatible chemicals during transit.
Chemical Inventory Status: Listed on most international chemical inventories, including US TSCA, EU REACH, Canadian DSL, Australian AICS, Japanese ENCS.
Labeling Requirements: Signal word “Warning”, pictograms depicting aquatic and human health hazards per GHS.
Regulated Uses: Approved for specific seed treatment only. Restricted use by certified operators in many jurisdictions.
Safety Review: Evaluated by US EPA, EU ECHA, and Food and Agriculture Organization (FAO); risk management measures mandated for worker and bystander safety.
Community Right-to-Know: Notification and record-keeping required in numerous countries; transport and storage conditions subject to local hazardous chemical laws.
Other Regulations: Overarching prohibitions on release to water bodies; waste and emissions limited per environment protection acts.
