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Product Name: Carbaspirin Calcium
Chemical Name: Calcium acetylsalicylate
Synonyms: Calcium aspirin, Calcium 2-(acetoxy)benzoate
Molecular Formula: C18H14CaO9
CAS Number: 5749-67-7
Recommended Use: Pharmaceutical intermediate, analgesic agent, anti-inflammatory applications
Supplier Details: Include name, address, emergency contact number on packaging
Emergency Contact: Local poison control center or emergency services
Restrictions on Use: Intended for use by trained personnel in laboratory and industrial settings
Hazard Classification: Acute oral toxicity (Category 4), Eye irritation (Category 2A), Skin irritation (Category 3), Respiratory irritation
GHS Label Elements: Warning symbol (exclamation mark), Signal word: Warning
Hazard Statements: Harmful if swallowed, causes eye irritation, may cause skin irritation, inhalation may trigger respiratory symptoms
Precautionary Statements: Wash exposed areas after handling, avoid breathing dust, wear protective equipment, use ventilation during handling
Potential Health Effects: Exposure can cause gastrointestinal distress, headache, nausea, coughing, redness, stinging in eyes and on skin
Environmental Effects: Possible risk for aquatic environments if released in significant quantity
Unknown Acute Toxicity: No complete data for mixture; hazardous components present
Chemical Identity: Calcium acetylsalicylate
CAS Number: 5749-67-7
Concentration: 98–100 %
Impurities: Trace amounts of salicylic acid and calcium carbonate may remain from synthesis
Additives: None reported
Other Ingredients: No hazardous components present above reportable thresholds
Inhalation: Move affected person to fresh air, monitor for respiratory symptoms, seek medical attention if breathing difficulty develops or persists
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of water and mild soap, seek medical help if irritation remains
Eye Contact: Rinse immediately with plenty of water for 15 minutes, keep eyelids open, remove contact lenses, consult a physician
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical staff, obtain medical attention if large amounts ingested or symptoms appear
Notes to Physician: Symptomatic treatment required, possible risk of metabolic acidosis and electrolyte imbalance after significant ingestion
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jets may spread powder
Specific Hazards: Decomposition can release carbon oxides, calcium oxides, irritating fumes; powder may form explosive dust/air mixtures
Protective Equipment: Self-contained breathing apparatus (SCBA), full protective clothing
Instructions: Remove containers from fire area if safe, control run-off to avoid environmental contamination
Personal Precautions: Wear gloves, mask, eye protection, appropriate clothing to avoid dust exposure
Emergency Procedures: Remove non-essential personnel from spill area, ventilate area
Containment: Avoid raising dust, sweep up carefully, collect spilled material in labeled waste container
Clean-Up Methods: Mop or wash residue with plenty of water; use HEPA vacuum for dust
Environmental Precautions: Prevent entry into drains, surface water, soil, or groundwater
Disposal: Dispose of in accordance with local, regional, national regulations
Handling: Use in well-ventilated areas, avoid inhalation of dust, avoid contact with skin and eyes, do not eat, drink, or smoke during use
Technical Measures: Ground/bond container and receiving equipment to reduce electrostatic hazard
Storage Conditions: Store in tightly closed original container at room temperature (15–25°C), protect from moisture, light and incompatible materials
Incompatible Materials: Strong oxidizers, acids, strong bases
Special Requirements: Keep away from foodstuffs, out of reach of children, handle only with trained personnel
Control Parameters: No occupational exposure limit (OEL) set; adopt a precautionary approach
Engineering Controls: Local exhaust ventilation, fume hood for laboratory work, enclosures for dust generation
Personal Protective Equipment: Nitrile gloves, safety goggles, lab coat or coveralls, dust-resistant mask or respirator (e.g. N95 or P2 standard if dust risk exists)
Hygiene Measures: Wash hands, face after handling, remove contaminated clothing, do not reuse contaminated garments until washed
Environmental Exposure Controls: Prevent workplace release to environment; use appropriate containment and waste management systems
Appearance: White to off-white crystalline powder
Odor: Mild, slightly acetic
Odor Threshold: Not established
pH: 6–8 (in water suspension)
Melting Point: Decomposes above 130°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not flammable; dust can form explosive mixtures with air
Evaporation Rate: Not applicable
Flammability: Not classified as flammable, but airborne dust is potentially explosive
Vapor Pressure: Not measurable (solid at room temperature)
Relative Density: Approx. 1.8 g/cm³
Solubility in Water: Readily soluble
Partition Coefficient (n-octanol/water): Not determined
Auto-Ignition Temperature: No data available
Decomposition Temperature: 130°C and above
Viscosity: Not applicable (solid)
Other Properties: Hygroscopic (absorbs moisture from air)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive with most substances during normal conditions
Conditions to Avoid: Exposure to moisture, heat, sources of ignition
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, calcium oxide, irritating organic fumes
Polymerization: Not known to occur
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Irritation to respiratory tract, skin, eyes, gastrointestinal distress after ingestion
Chronic Effects: Long-term exposure may cause kidney or liver effects, respiratory sensitization is possible
LD50 (oral, rat): Estimated range 1500–2000 mg/kg
Symptoms: Nausea, headache, drowsiness, ringing in ears, confusion (with high doses), allergic skin reactions in sensitive persons
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No confirmed reports, based on known data for acetylsalicylate compounds
Mutagenicity: Not expected based on structure and available research
Medical Conditions Aggravated by Exposure: Asthma, known salicylate sensitivity, pre-existing skin or respiratory disorders, kidney disease
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: High solubility; may migrate through soil into groundwater
Ecotoxicity: Limited ecotoxic data, expected to be of moderate hazard to aquatic life at significant concentrations
Persistence and Degradability: Readily biodegradable; breakdown expected by hydrolysis and bacterial action
Other Adverse Effects: No known significant effects, avoid uncontrolled release to water bodies
Waste Treatment Methods: Collect and contain waste in secure labeled containers
Disposal of Product: Incinerate in approved facility or send to licensed chemical waste disposal contractor
Disposal of Contaminated Packaging: Rinse containers, dispose in accordance with local regulations, do not reuse packaging
Precautions: Do not dispose to sewage, surface water, or soil; minimize environmental release during clean-up
Legal Requirements: Comply with national and regional waste management regulations
UN Number: Not classified as a dangerous good for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Classes: None assigned
Packing Group: None
Environmental Hazards: Not considered a marine pollutant under IMDG
Special Transport Precautions: Keep container tightly closed, protect from humidity and extreme temperatures during shipment
Regulatory References: Refer to ADR, RID, IMDG, IATA for up-to-date information
Safety, Health and Environmental Regulations: Subject to workplace safety and chemical handling rules under OSHA, WHMIS, REACH as applicable
Labeling Requirements: Label with product identification, hazard pictograms, precautionary and hazard statements in accordance with GHS
Inventory Status: Registered or listed in most chemical inventories (check country-specific requirements)
Other Regulatory Information: Not subject to special restrictions on use, but product must be handled in line with prevailing health and safety guidance
Right-to-Know: Information available to workers under community right-to-know laws and Hazard Communication Standards
