© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Canrenoate Potassium
Chemical Formula: C22H29KO5
SYNONYMS: Potassium Canrenoate; 3-[(7α,17α)-17-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]propanoate potassium salt
CAS Number: 288-94-8
Intended Use: Pharmaceutical intermediate, research, not for food or household use
Manufacturer: [Insert manufacturer name]
Emergency Contact: [Insert emergency contact]
GHS Classification: Not classified as hazardous according to GHS criteria
Signal Word: None
Hazard Statements: Not applicable
Precautionary Statements: Minimize dust generation. Avoid inhalation and contact with skin and eyes.
Physical Hazards: May form dust clouds if handled carelessly. No known explosive hazard.
Health Hazards: May be harmful if swallowed. Can cause irritation to skin or eyes upon direct contact.
Environmental Hazards: Avoid release to the environment, persistence or effects not well studied.
Chemical Name: Canrenoate Potassium
Common Names: Potassium Canrenoate
PERCENTAGE: ≥99% (as per manufacturer’s specification)
Impurities: Minor impurities unrelated to pharmacology, <0.5%
Molecular Weight: 408.6 g/mol
EC Number: 636-698-6
GENERAL ADVICE: Remove from exposure area. Seek medical attention if symptoms persist.
INHALATION: Move person to fresh air. Keep at rest in position comfortable for breathing. If breathing is difficult, give oxygen and call a physician.
SKIN CONTACT: Wash with plenty of soap and water. Remove contaminated clothes and wash before reuse.
EYE CONTACT: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do.
INGESTION: Do not induce vomiting. Rinse mouth. Give water if conscious. Seek medical advice.
SUITABLE EXTINGUISHING MEDIA: Use dry chemical powder, water spray, foam, or carbon dioxide for small fires.
FIRE HAZARDS: Burning can produce irritating, toxic, or corrosive fumes. Avoid inhalation of decomposition products.
HAZARDOUS COMBUSTION PRODUCTS: Carbon monoxide, carbon dioxide, potassium oxides, unknown toxic gases.
PROTECTIVE EQUIPMENT: Firefighters need self-contained breathing apparatus and full protective gear.
SPECIFIC METHODS: Prevent fire runoff from contaminating drains or watercourses.
PERSONAL PRECAUTIONS: Avoid inhalation, ingestion, and contact with skin and eyes. Wear suitable protective clothing, gloves, and safety goggles.
ENVIRONMENTAL PRECAUTIONS: Keep out of drains, sewers, or soil. Report spills to appropriate authorities.
CONTAINMENT AND CLEANUP: Vacuum or sweep up and place in suitable container for disposal. Avoid dust formation. Ventilate area. Wash spill site after material pick-up is complete.
SAFE HANDLING PRACTICES: Use only with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing.
STORAGE CONDITIONS: Store in tightly closed original container, in cool, dry, well-ventilated area. Keep away from incompatible substances such as strong oxidizing agents.
PACKAGING: Use containers that are compatible with organic salts and pharmaceuticals. Avoid cardboard for direct contact.
OCCUPATIONAL EXPOSURE LIMITS: Not established for this substance.
ENGINEERING CONTROLS: Use process enclosures, local exhaust ventilation, or other controls to avoid airborne exposure.
RESPIRATORY PROTECTION: Wear approved respiratory protection if dust or aerosols are generated.
SKIN PROTECTION: Wear chemical-resistant gloves, lab coat, and appropriate footwear.
EYE PROTECTION: Safety goggles or face shield.
HYGIENE MEASURES: Wash hands and face after handling compounds and before eating, drinking, or smoking.
APPEARANCE: White to off-white crystalline powder
ODOR: Odorless
ODOR THRESHOLD: Not available
pH (1% solution): Neutral to slightly alkaline
MELTING POINT: 228-232°C (decomposes)
BOILING POINT: Not available
FLASH POINT: Not established
VAPOR PRESSURE: Negligible
DENSITY: ~1.3 g/cm³
WATER SOLUBILITY: Freely soluble
PARTITION COEFFICIENT: Not available
VISCOSITY: Not applicable
AUTO-IGNITION TEMPERATURE: Not available
CHEMICAL STABILITY: Stable under normal temperatures and pressures in tightly closed containers.
POSSIBLE HAZARDOUS REACTIONS: None known under normal use.
CONDITIONS TO AVOID: Excessive heat, moisture, strong oxidizing agents.
INCOMPATIBLE MATERIALS: Strong acids, strong bases, and oxidizers; may react with these materials.
HAZARDOUS DECOMPOSITION PRODUCTS: Carbon dioxide, carbon monoxide, potassium compounds, traces of toxic gases.
LIKELY ROUTES OF EXPOSURE: Inhalation, skin and eye contact, ingestion.
ACUTE TOXICITY: Low toxicity based on structural similarity and testing data for related compounds. May cause mild irritation to skin, eyes, respiratory tract.
CHRONIC TOXICITY: No evidence for mutagenicity, carcinogenicity, or reproductive toxicity has emerged in published studies for this compound.
SYMPTOMS OF EXPOSURE: Eye or skin redness, coughing, gastrointestinal distress if swallowed.
LD50 (rat oral): >2000 mg/kg
SENSITIZATION: Not expected based on available data
OTHER INFORMATION: Seek medical evaluation for persistent symptoms.
ECOTOXICITY: Data not fully established. Avoid environmental release as a precaution.
AQUATIC TOXICITY: No significant fish, algae, or crustacean toxicity reported at likely exposure levels.
PERSISTENCE AND DEGRADABILITY: Not readily biodegradable; environmental fate data incomplete.
BIOACCUMULATIVE POTENTIAL: Low based on log Kow estimation.
MOBILITY IN SOIL: May leach, especially in agricultural or medical use scenarios.
OTHER ADVERSE EFFECTS: No known significant effects or hazards.
WASTE DISPOSAL METHODS: Dispose of in accordance with federal, state, and local environmental control regulations. Use a licensed chemical waste disposal contractor.
CONTAMINATED PACKAGING: Empty containers should be decontaminated before disposal or recycling.
EUROPEAN WASTE CODE: 18 01 06 or similar for pharmaceutical waste.
DO NOT: Release into public drains or soils.
UN NUMBER: Not regulated for transport
TRANSPORT HAZARD CLASS: Not classified as dangerous goods
PACKING GROUP: Not applicable
MARINE POLLUTANT: Not applicable
SPECIAL PRECAUTIONS: Avoid direct sunlight, protect from moisture during transport. Keep tightly closed and upright.
TSCA STATUS: Not listed individually (research and pharmaceutical use only)
SARA TITLE III: Not subject to Section 313 reporting.
REACH REGISTRATION NUMBER: Not listed
WHMIS CLASSIFICATION (Canada): Not controlled
EU CLASSIFICATION: Not hazardous according to Regulation (EC) No 1272/2008 (CLP)
OTHER REGULATIONS: Not listed as a controlled drug. Users should check national, regional, or local regulations for workplace health and safety rules as well as waste disposal obligations.
