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Product Name: Camostat Mesylate
Chemical Formula: C21H25N4O5S · CH4O3S
Description: Known for its application in research, especially relating to treatments for pancreatitis and anti-viral investigations, camostat mesylate comes as a white to off-white powder. Most people in labs recognize this molecule for its active role as a serine protease inhibitor.
Main Hazards: Inhalation, ingestion, or skin contact can lead to irritation. High concentrations may cause respiratory discomfort and eye sensitivity in exposed individuals.
Warning Symbols: The compound usually earns a warning symbol for potential toxicity and irritation.
Risk Phrases: Reports mention risks for those working without proper safeguards, such as skin irritation and specific toxicity symptoms with repeated or large exposures.
Chemical Identity: Camostat Mesylate
CAS Number: 59721-29-8
Impurities: Usually deemed pure in reagent-grade packaging, trace solvents from synthesis can appear, but good suppliers publish residual solvent levels.
Synonyms: Empirical studies often reference alternative names like FOY-305.
Inhalation: Move to fresh air instantly. Persistent symptoms deserve real medical attention.
Skin Contact: Rinse exposed skin with plenty of water. Remove contaminated clothing.
Eye Contact: Flush eyes with clean water for several minutes.
Ingestion: Rinse mouth with water if swallowed accidentally and seek medical advice if discomfort arises.
Suitable Extinguishing Media: Carbon dioxide, foam, or dry chemical powder usually put out localized fires involving organic powders.
Specific Hazards: Combustion generates hazardous fumes, including carbon oxides, nitrogen oxides, and sulfur oxides.
Protective Actions: Firefighters must use self-contained breathing gear and standard protective clothing in case of significant fires.
Cleanup Methods: Use non-sparking tools to sweep up spillage. Use absorbent material for dusty or thin spread.
Environmental Precautions: Prevent further leakage into drains, soil, or water sources. Proper ventilation curtails vapor accumulation.
Personal Precautions: Gloves, masks, and goggles protect staff from direct or indirect exposure.
Handling: Always practice minimizing dust generation and inhalation. Gloves, goggles, and lab coats reduce the chance of skin or eye issues.
Storage: Keep tightly sealed containers in cool, dry, and ventilated storage areas. Avoid direct light and incompatible substances like strong oxidizers.
Engineering Controls: Use local exhaust ventilation or chemical fume hoods for open handling.
Personal Protective Equipment: Gloves and goggles shield skin and eyes. Dust masks or respirators add another layer against airborne particles.
Exposure Limits: No published occupational exposure guidelines for camostat mesylate, though common sense argues for strict adherence to PPE rules.
Appearance: White to off-white powder, crystalline structure.
Solubility: Dissolves in water and DMSO.
Melting Point: Ranges around 180-185°C, depending on purity.
Odor: No noticeable odor.
Boiling Point, pH, Flash Point: Data not widely published for this molecule; users focus more on solubility and stability.
Chemical Stability: Stays stable at room temperature in dry environments. Hydrolyzes slowly over time if exposed to moisture.
Conditions to Avoid: Avoid moist air, high heat, and strong acids or bases.
Hazardous Decomposition Products: Burning or long exposure to high heat can produce toxic gases like nitrogen, sulfur, and carbon oxides.
Acute Effects: Skin, eye, and respiratory tract irritation appear on acute exposure.
Chronic Effects: No published evidence for carcinogenic properties, but chronic inhalation or ingestion risks demand cautious practices.
Possible Symptoms: Headache, dizziness, nausea, respiratory symptoms after large-scale exposure.
Routes of Exposure: Ingestion, inhalation, dermal, and ocular.
Environmental Fate: Data scarce, so avoid large spills and environmental releases by disposing through established chemical waste management.
Aquatic Effects: No published toxicity data on aquatic species to date, but as with most bioactive compounds, risk to waterways should be assumed.
Degradability: Not easily biodegradable; persistent if released.
Waste Disposal Methods: Use licensed chemical waste contractors. Do not flush or pour down any drain.
Regulatory Waste Codes: Local, regional, or national guidelines decide hazardous waste codes for organic chemicals.
UN Number: No universal UN number assigned for this compound.
Shipping Class: Typically handled as non-dangerous goods for transportation in small, packaged quantities.
Special Precautions: Secure containers, avoid rough handling, keep away from moisture and incompatible chemicals during transport.
TSCA, REACH Status: Research chemical status—legal uses bound by national and international chemical control laws.
Labelling: Labels mention risks for skin, eyes, and respiratory tract.
Workplace Regulations: General chemical laboratory rules set standards for safe handling and use.
