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Product Name: Brivaracetam – Reagent
Chemical Formula: C11H20N2O2
CAS Number: 357336-20-0
Product Use: Chemical reagent for research and laboratory use, not for use in drug, food, or human applications
Manufacturer/Supplier: Laboratory chemical supplier, contact information typically available on purchase invoice
Emergency Contact Number: Local poison control, chemical safety officer within workplace
Synonyms: Briviact, UCB-34714
UN Number: Not classified under a UN number for transportation purposes
Classification: Not classified as hazardous according to GHS, but can have health effects through excessive exposure
Signal Word: None required under GHS; caution advised
Hazard Statements: May cause respiratory and eye irritation, sensitization through prolonged or repeated skin contact cannot be excluded
Precautionary Statements: Avoid inhalation or contact with skin and eyes, always wear appropriate personal protective equipment
Physical Hazards: Presents no unusual chemical hazard when handled as recommended
Environmental Hazards: Potential for environmental harm if released in large quantities; prevent spills from entering groundwater or sewers
Chemical Name: Brivaracetam
Common Name: Brivaracetam
Purity: ≥98% research grade
Impurities: Trace organic solvents (<1%), water (<0.5%)
Inert Carriers: None added
Additives: No stabilizers or colorants
General Advice: Move affected individual away from exposure source
Inhalation: Move to fresh air; contact a physician if symptoms develop, provide oxygen if breathing is difficult
Eye Contact: Rinse cautiously with water for at least 15 minutes; remove contact lenses if present and easy to do; consult healthcare provider if irritation persists
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek medical attention for symptoms or prolonged exposure
Ingestion: Rinse mouth thoroughly, drink water, do not induce vomiting, seek immediate medical advice
Symptoms and Effects: Irritation of eyes, skin, mucous membranes; headache, dizziness if inhaled
Suitable Extinguishing Media: Water spray, dry powder, carbon dioxide, foam
Unsuitable Media: Do not use high-pressure water jets on surrounding chemical containers
Hazardous Combustion Products: May release carbon oxides and nitrogen oxides under fire conditions
Specific Hazards: Fine particulates might present dust explosion risk under rare circumstances
Personal Protection for Firefighters: Full protective clothing, positive pressure self-contained breathing apparatus
Special Firefighting Procedures: Cool non-ignited containers with water spray, prevent runoff from entering surface water drains
Personal Precautions: Use gloves, laboratory goggles, suitable respiratory protection for heavy dust
Environmental Precautions: Avoid discharge to the environment, do not allow to reach water sources or soil
Cleaning Methods: Absorb with inert material (vermiculite, dry sand), sweep up material, place in sealed chemical waste container
Decontamination: Wash affected area with mild detergent and water, ventilate room, dispose used materials as hazardous waste
Spill Response: Emergency procedures communicate danger and evacuate unprotected personnel
Safe Handling: Practice good laboratory hygiene, use only in well-ventilated workspaces, avoid aerosol generation, never eat or drink in handling areas
Storage Conditions: Store in tightly closed container, protected from moisture and direct sunlight, keep between 2–8°C (refrigerated), segregate from incompatible substances such as oxidizers and acids
Incompatibilities: Strong oxidizing agents, acids, bases
Storage Containers: Use only compatible chemical-resistant containers with clear labeling
Special Storage Notes: Secure from unauthorized access, prevent container damage
Permissible Exposure Limits: Not established; minimize exposure as precaution
Engineering Controls: Fume hood or local exhaust ventilation recommended
Personal Protective Equipment: Splash-proof safety goggles, chemical-resistant gloves (nitrile or neoprene), laboratory coat, optionally a dust mask or half-face respirator where appropriate
Hygiene Measures: Wash hands and face after handling, avoid cross contamination by removing PPE before leaving the lab, wash contaminated clothing before reuse
Environmental Exposure Controls: Prevent chemical from entering waterways or drains
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 116–118°C
Boiling Point: Not volatile at normal atmospheric pressure
Solubility: Soluble in organic solvents (methanol, acetonitrile), sparingly soluble in water
pH: Not applicable as solid; near neutral in dilute solution
Vapor Pressure: Negligible at room temperature
Flash Point: Data not available, assumed high due to structure
Density: Approx. 1.1–1.2 g/cm³
Stability in Solution: Stable under recommended conditions
Chemical Stability: Stable under standard laboratory conditions (dry, cool, protected from light)
Reactivity: Avoid strong oxidizers and acids
Decomposition: May decompose at high temperatures, releasing irritating or toxic fumes
Polymerization: Not expected to occur
Conditions to Avoid: Moisture, extreme heat, exposure to incompatible chemicals
Hazardous Reactions: No hazardous reactions anticipated if handled and stored properly
Acute Toxicity: Oral LD50 for rodents above 2000 mg/kg (data based on analogous compounds)
Inhalation: Dust may cause headache, respiratory tract irritation, mild nausea upon significant exposure
Skin Contact: Possible temporary irritation
Eye Contact: Can lead to redness, pain, tearing upon direct exposure
Chronic Exposure: Data limited; research grade chemical, so avoid repeated contact
Carcinogenicity, Mutagenicity, Reproductive Effects: Not listed by IARC, NTP, or OSHA
Sensitization: Possible skin or respiratory sensitizer in rare cases
Other Information: Not enough long-term data in humans to fully characterize toxicity
Ecotoxicity: Not fully assessed, but expected to present risk to aquatic organisms at high concentrations
Persistence and Degradability: Likely to be partially biodegradable; significant release may affect microbial populations
Bioaccumulative Potential: Limited potential due to molecular structure, unlikely to accumulate under typical laboratory use
Mobility in Soil: Low to moderate; unlikely to travel far from point of release
Other Effects: Prevent chemical from entering streams, lakes, or public water systems
Disposal Method: Treat as hazardous chemical waste, incinerate or landfilled in accordance with local, state, federal, and national regulations
Container Disposal: Rinse with appropriate solvent, destroy or dispose in compliance with hazardous waste requirements
Special Notes: Do not pour residues or rinsates into sinks or municipal waste
Waste Codes: Consult local authorities for official classification based on content and contamination
Recycling: Not recommended due to potential health and environmental risks
UN Number: Not regulated for ground, sea, or air transport
Transport Name: Not classified as hazardous under ADR/RID, IATA, or IMDG
Packing Group: Not applicable
Hazard Class: Not subject to hazard classification
Labeling Requirements: Follow good packaging practice, label clearly as laboratory reagent with appropriate hazard warning signage
Special Precautions: Avoid extreme temperatures, secure package to prevent breakage
OSHA Status: Not regulated as hazardous
TSCA Status: Not listed for commercial use
REACH Status: Subject to laboratory chemical use provisions; not registered for bulk use
SARA Title III: Not subject to Section 313 reporting
IARC, NTP, ACGIH Listings: Not classified as carcinogenic
California Proposition 65: Substance not listed
Other Regulatory Notes: Researchers and occupational users must comply with chemical handling and disposal rules of their country or state
