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Product Name: Breviscapine
Chemical Name: 4',5,6-Trihydroxyflavone-7-O-glucuronide
Synonyms: Breviscapine extract, Erigeron breviscapus extract
CAS Number: 97753-54-9
Molecular Formula: C21H18O12
Molecular Weight: 462.36 g/mol
Product Use: Pharmaceutical intermediate, research, dietary supplement manufacturing
Manufacturer: [Company-specific details]
Contact Information: [Company-specific emergency phone number, address]
GHS Classification: Not classified as hazardous according to current GHS standards
Signal Word: None
Hazard Statements: None specified for typical handling, but high concentrations may irritate eyes or respiratory tract
Pictograms: None
Precautionary Statements: Avoid inhalation of powders and contact with eyes; maintain local ventilation at processing points
Potential Health Effects: Powdered product can cause transient discomfort to eyes and mucosal surfaces; ingestion for non-approved purposes not advised
Main Ingredient: Breviscapine (Erigeron breviscapus extract, >90% purity)
Impurities: Trace natural plant constituents (<2%)
Excipients: None unless blended with carrier or diluents
Formula: C21H18O12
Physical Form: Fine pale yellow crystalline powder or solid
Water Content: Typically <5%
Inhalation: Move person to fresh air, support breathing if discomfort continues, seek medical attention if symptoms persist
Eye Contact: Rinse thoroughly with plenty of clean water, remove any contact lenses, continue rinsing for several minutes if irritation remains
Skin Contact: Remove contaminated clothing, wash skin fully with soap and water
Ingestion: Do not give anything by mouth if person is unconscious, rinse mouth, consult with healthcare professional if large quantity swallowed
Symptoms to Watch For: Itchy eyes, mild cough, short-term throat irritation, rare allergic reaction
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, or water spray
Unsuitable Extinguishing Media: Direct high-pressure water stream may disperse powders
Specific Hazards: Combustion produces carbon oxides and other potentially irritating gases
Protective Equipment: Wear full firefighting gear and self-contained breathing apparatus in closed spaces
Advice for Firefighters: Keep containers cool with water mist, avoid inhaling smoke or dust, control runoff
Personal Precautions: Avoid dust generation, ventilate area, use proper personal protective equipment
Environmental Precautions: Prevent entry into drains or water courses
Clean-up Methods: Collect spilled material using damp cloth or vacuum fitted with HEPA filter, place in suitable container for disposal
Small Spills: Wipe or mop up with compatible absorbent
Large Spills: Scoop into secure, labeled containers and manage as chemical waste
Handling: Use in well-ventilated areas, avoid breathing dust, wear protective eyewear and gloves, keep away from food and drinks
Storage Requirements: Store tightly sealed in cool, dry place, away from direct sunlight, strong oxidizers, or sources of ignition
Container Compatibility: Use non-reactive, well-labeled packaging
Special Precautions: Keep container upright and tightly closed, handle in accordance with good industrial hygiene practices
Engineering Controls: Provide local exhaust ventilation where dust can form
Exposure Limits: No specific occupational limits established for Breviscapine
Respiratory Protection: Wear NIOSH-approved particulate respirator if workplace dust exceeds nuisance levels
Skin Protection: Wear chemical-resistant gloves (e.g. nitrile, latex), laboratory coat or appropriate garment
Eye Protection: Safety glasses with side shields or chemical goggles
Hygiene Measures: Wash hands before breaks, after handling, and at end of work
Environmental Controls: Protect from uncontrolled environmental release
Appearance: Pale yellow to off-white crystalline powder
Odor: Mild, slightly plant-like
Melting Point: 271-275°C
Boiling Point: Not available, decomposes before boiling
Solubility: Slightly soluble in water, soluble in methanol and ethanol
pH: Not applicable for solid form
Density: Approximately 1.7 g/cm³
Partition Coefficient: Not established
Other Properties: No significant volatility, dust can form under vigorous processing
Chemical Stability: Stable under normal storage and handling conditions
Conditions to Avoid: Uncontrolled moisture, high temperatures, light exposure, open flames
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition: May release carbon dioxide, carbon monoxide, and minor organic decomposition products during fire
Polymerization: Not expected to occur under normal conditions
Likely Routes of Exposure: Inhalation, skin or eye contact, accidental ingestion
Acute Toxicity: Low, limited evidence of toxicity at typical exposure levels during handling
Chronic Toxicity: No reports of chronic effects in industrial settings
Skin/Respiratory Sensitization: Uncommon, may affect sensitive individuals
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA, or EU regulations
Mutagenicity: Not identified as mutagenic based on available studies
Reproductive Effects: No conclusive evidence in animal or cellular studies so far
Symptoms of Exposure: Mild irritation, rare allergic response
Ecotoxicity: No significant hazardous effects predicted to aquatic or terrestrial life at environmental concentrations
Persistence and Degradability: Product is expected to biodegrade in soil and water to simpler compounds
Bioaccumulation Potential: Likely low, breakdown occurs in environmental matrices
Mobility in Soil: Moderately mobile due to partial water solubility
Other Adverse Effects: Avoid direct, large-scale release to waterways; during normal use minimal impact anticipated
Methods of Disposal: Comply with local, state, and federal regulations; preferred route is incineration in a licensed facility
Contaminated Packaging: Triple rinse and offer clean containers for recycling or dispose of as hazardous waste
Disposal Precautions: Prevent environmental contamination, do not flush large amounts to sewer
Special Considerations: Consult with waste handler or environmental officer as requirements vary by location
UN Number: Not regulated for ground, sea, or air transport
Proper Shipping Name: Not classified as a dangerous good
Transport Hazard Class: Not applicable
Packing Group: Not required
Environmental Hazards: Product is not a marine pollutant
Special Transport Precautions: Protect packaging from puncture, moisture, major vibration; ship with standard chemical precaution documentation
US Regulations: Not listed as hazardous under SARA Title III, CERCLA or TSCA; intended for use by qualified personnel
EU Regulations: Not classified as dangerous according to CLP Regulation (EC No. 1272/2008)
Canadian Regulations: Not specifically listed on DSL/NDSL
Labelling Requirements: Use workplace labeling that highlights dust control and exposure minimization
Other Regulations: National/local requirements on occupational health, safe chemical management, and storage apply
Restrictions: Pharmaceutical or research use only, not for general consumer applications without regulatory approval
