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Product Name: Bethanechol Chloride
Chemical Formula: C7H17ClN2O2
Synonyms: Urecholine, Myotonachol, Duvoid
CAS Number: 590-63-6
Recommended Use: Pharmaceutical applications, laboratory reagent
Manufacturer: Contact supplier or manufacturer for further details
Contact Information: Emergency phone number and address are located on product packaging or supplier documentation
Hazard Classification: Acute toxicity (oral), Hazardous to eyes, Harmful if inhaled or swallowed
Signal Word: Warning
Hazard Statements: Causes slight to moderate irritation to eyes, respiratory tract, gastrointestinal tract; may accelerate cholinergic effects including sweating, salivation, abdominal discomfort, and muscle cramps
Precautionary Statements: Avoid inhaling dust, do not ingest, wash hands after handling, wear appropriate PPE
Route of Exposure: Inhalation, ingestion, skin/eye contact
Symbols: Exclamation mark (acute toxicity indication)
Target Organs: Cholinergic system, musculoskeletal, gastrointestinal, cardiovascular systems
Chemical Name: Bethanechol Chloride
Concentration: 99% or higher of active pharmaceutical ingredient
Impurities: Trace organic or inorganic substances may be present based on synthesis method; typically less than 1%
Other Ingredients: No added excipients in raw API form
Molecular Weight: 196.7 g/mol
Component Disclosure: Full composition supplied with certificate of analysis on request
Regulatory Status: Classified as a pharmaceutical precursor in most regions
General Advice: Remove from exposure source, seek medical attention as soon as possible
Inhalation: Move person to fresh air, monitor breathing, provide oxygen if breathing becomes difficult, seek medical attention immediately
Skin Contact: Remove contaminated clothing, wash thoroughly with soap and water, consult a physician if adverse symptoms develop
Eye Contact: Flush eyes gently with plenty of water for at least 15 minutes, remove contact lenses if present, obtain emergency medical care
Ingestion: Rinse mouth, do not induce vomiting unless directed, give water if conscious, seek immediate medical care
Most Important Symptoms and Effects: Excess sweating, increased salivation, blurred vision, low blood pressure, muscle cramps, vomiting, diarrhea
Medical Notes: Emergency physicians should monitor for severe cholinergic syndrome and provide symptomatic care
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Not Suitable: Direct high-pressure water jet on burning product
Special Hazards: In case of fire, hydrochloric fumes, nitrogen oxides, carbon monoxide, and carbon dioxide may be released
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Fire / Explosion Hazard: Does not present unusual fire or explosion hazard under normal handling; product is non-flammable but decomposes at high temperatures
Advice for Firefighters: Approach upwind if possible, keep containers cool with water spray, prevent runoff from entering drains
Personal Precautions: Evacuate unnecessary personnel, avoid dust formation, avoid contact with skin, eyes, and clothing
Protective Equipment: Use gloves, lab coat, tightly fitted goggles, dust mask or respirator with particle filter
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not allow product to reach drains, water courses, or soil
Methods for Cleaning Up: Sweep up and collect in a suitable, labeled container for disposal, ventilate area, clean contaminated surfaces thoroughly with water and appropriate detergents
Spill Response: Small amounts: wipe up or use absorbent material; large amounts: use appropriate containment and call hazardous spill response team
Safe Handling: Handle in a chemical fume hood, avoid dust generation, wear gloves and protective clothing as recommended
Hygiene Procedures: Wash hands and exposed skin thoroughly after handling, avoid eating, drinking, or smoking near product
Storage Conditions: Store cool and dry, keep container tightly closed away from direct sunlight, incompatible chemicals, acids, strong oxidizers
Storage Temperature: Between 2°C – 8°C, unless otherwise specified by the manufacturer
Container Requirements: Use protective packaging, close tightly to prevent moisture entry, clearly label with proper identification
Handling Precautions: Do not breathe dust, avoid exposure to moisture and sources of ignition, minimize physical and chemical stress
Occupational Exposure Limit (OEL): No specific OSHA or ACGIH value, use best practice controls and minimize exposure
Engineering Controls: Fume hood, local exhaust ventilation, closed handling systems where possible
Personal Protective Equipment: Chemical resistant gloves (nitrile or neoprene), lab coat, eye protection with side shields or safety goggles, disposable respirator with filter P2 or better for dust
Skin Protection: Protective clothing, avoid skin contact and frequent hand washing
Respiratory Protection: Dust mask or respirator suitable for handling fine powders
Environmental Controls: Prevent release to the environment, implement procedures for immediate containment of spills
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 5.0–6.0 (aqueous solution)
Melting Point/Freezing Point: 210°C–215°C (decomposes)
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Not determined
Evaporation Rate: Not applicable
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Solubility: Freely soluble in water, slightly soluble in alcohol, insoluble in most organic solvents
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Approximately 210°C
Viscosity: Not applicable
Other Data: Stable under recommended storage conditions, sensitive to moisture and heat
Chemical Stability: Stable in dry, cool, well-ventilated environments, sensitive to prolonged exposure to moisture and air
Reactivity: No dangerous reactions known under normal use
Possibility of Hazardous Reactions: Decomposes at high temperatures releasing toxic fumes such as hydrogen chloride, carbon monoxide
Conditions to Avoid: Heat, moisture, open flame, incompatible chemicals such as strong acids and oxidizers
Incompatible Materials: Strong oxidizers, strong acids, alkali agents, reducing agents
Hazardous Decomposition Products: Chlorinated and nitrogenous gases, carbon oxides
Acute Toxicity: LD50 (oral, rat): approx. 50 mg/kg, toxicity depends on route and individual sensitivity
Chronic Toxicity: Long-term exposure may cause cholinergic overstimulation, hypersensitivity reactions
Skin Corrosion/Irritation: May cause mild irritation on contact
Eye Damage/Irritation: Risk of conjunctival redness or irritation, especially with powder contact
Respiratory Sensitization: Inhalation of dust may cause coughing, sore throat, and increased secretions
Germ Cell Mutagenicity: No data available
Carcinogenicity: Not classified as carcinogenic by major agencies
Reproductive Toxicity: No conclusive data
Repeated Dose Toxicity: Chronic exposure to sub-acute doses may lead to abdominal discomfort, weakness, excessive sweating, and salivation
Medical Conditions Aggravated by Exposure: Asthma, respiratory disorders, cardiovascular illness, hyperthyroidism
Ecotoxicity: Harmful to aquatic organisms in case of discharge to environments, limited data available for full-scale environmental impact
Persistence and Degradability: Compound is presumed biodegradable with time but actual kinetics are not well documented
Bioaccumulative Potential: Low potential due to rapid breakdown in biological environments
Mobility in Soil: Dissolves easily in water, moderate migration possible from spillage sites
Other Adverse Effects: Avoid contamination of surface waters, groundwater, and natural habitats; chemicals of pharmaceutical nature often disrupt aquatic microflora
Precautionary Statement: Do not pour leftovers or solutions containing the product into drains, soils, or open waters
Waste Handling: Do not dispose of via domestic waste or drains, follow local and national hazardous chemical disposal regulations
Disposal Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber; landfill in approved facility as permitted; strongly discouraged to flush into sewer
Contaminated Packaging: Dispose of as unused product, clean thoroughly before recycling or follow hazardous waste disposal laws
Special Precautions: Minimize exposure of waste to heat and moisture to limit unwanted decomposition; use secondary containment for transport to disposal site
Regulatory Compliance: Confirm with environmental and waste regulatory authorities before disposal
UN Number: Not classified as dangerous for transport according to international regulations
Proper Shipping Name: Bethanechol Chloride
Transport Hazard Class: Not regulated under ADR/RID/IMDG/IATA
Packing Group: Not assigned
Labeling Requirements: Standard chemical labeling, not requiring additional hazard labels
Special Precautions: Protect from moisture and heat during transit, ensure robust containment
Other Information: Shipment of large quantities may need consultation with the carrier and adherence to country-specific rules regarding pharmaceutical substances
International Inventories: Bethanechol Chloride may not be listed on chemical inventories such as TSCA, EINECS, DSL due to pharmaceutical status
Relevant Regulations: Subject to pharmaceutical, workplace safety, and environmental regulations where applicable
Labelling Requirements: Conform to pharmaceutical and hazardous substance labeling standards, include recommendations for safe handling
SARA Title III: Does not appear under SARA 313 regulated chemicals
California Proposition 65: Not listed as a carcinogen or reproductive toxin
REACH Status (EU): Use is controlled under medical product laws; workplace use monitored by REACH and CLP where relevant
Other Local/Regional Information: Regulations may vary globally, confirm compliance with country or region of use
Training Advice: Ensure users understand safe handling, risks, and emergency procedures through appropriate workplace training
