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Material Safety Data Sheet: Benzethonium Chloride

Identification

Product Name: Benzethonium Chloride
Chemical Formula: C27H42ClNO2
Synonyms: Hyamine 1622, BTC, Diisobutylphenoxyethoxyethyl dimethyl benzyl ammonium chloride
CAS Number: 121-54-0
Recommended Use: Antimicrobial agent, disinfectant, preservative
Supplier Details: Reach out to chemical vendors or distributors for company-specific contact information
Emergency Contact: Refer to local, regional, or national poison control centers and emergency hotlines

Hazard Identification

Classification: Acute toxicity (oral, dermal, inhalation), Skin corrosion/irritation, Eye damage/irritation, Environmental hazards
Signal Word: Danger
Hazard Statements: Toxic if swallowed or absorbed through skin, Causes severe skin burns and serious eye damage, Harmful to aquatic life with long lasting effects
Pictograms: Corrosive, Exclamation mark, Environment
Precautionary Statements: Avoid contact with skin, eyes, and clothing, Avoid release into the environment, Wear protective gloves, clothing, eye and face protection, Do not breathe dust or mists

Composition / Information on Ingredients

Chemical Name: Benzethonium Chloride
Concentration: 98-100% (varies depending on supplier and intended use)
Impurities: May contain trace amounts of related quaternary ammonium compounds, limited to regulated specifications
Additives: No intentional additives listed, some preparations dissolve in water or alcohol

First Aid Measures

Inhalation: Move person to fresh air immediately, provide artificial respiration if breathing slows or stops, seek prompt medical care
Skin Contact: Remove contaminated clothing, flush skin with copious amounts of water and mild soap, seek medical attention if irritation persists or burns appear
Eye Contact: Rinse cautiously with clean water for a minimum of 15 minutes, keep eyelids open, remove contact lenses, get medical attention right away
Ingestion: Rinse mouth thoroughly, do not induce vomiting, never give anything by mouth to an unconscious person, contact poison control or a physician urgently

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, foam, or dry chemical fire extinguishers
Specific Hazards: May emit toxic fumes such as hydrogen chloride and nitrogen oxides
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective clothing
Special Precautions: Evacuate area, stay upwind during fire, remove containers if safe to do so, use water spray to cool fire-exposed containers

Accidental Release Measures

Personal Precautions: Evacuate area, wear chemical-resistant gloves, goggles, boots, and protective clothing
Environmental Precautions: Prevent release to drains, sewers, and waterways, contain spillage using non-combustible absorbent materials such as sand or vermiculite
Clean-up Methods: Scoop up and transfer spilled product to clearly labeled disposal containers, wash area with water and detergent, ventilate area thoroughly

Handling and Storage

Handling: Handle with local exhaust or general dilution ventilation, avoid generating dust or aerosols, minimize splashing, wash hands after handling, keep container tightly closed
Storage: Store locked up, keep in original tightly closed container, store in cool, dry, well-ventilated area away from foodstuffs and incompatible substances such as strong oxidizers and acids, shield from direct sunlight and moisture, segregate from flammables and combustibles

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific occupational limits established, follow internal guidelines and regulations for chemical handling
Engineering Controls: Ensure good general ventilation, consider local exhaust at points of emission
Personal Protection: Eye/face protection (chemical safety goggles or face shield), hand protection (chemical-resistant gloves such as nitrile or neoprene), protective clothing (long-sleeved, chemical-resistant apron or gown), respiratory protection (if ventilation insufficient, use NIOSH-approved respirators for dust or mists)

Physical and Chemical Properties

Appearance: White or off-white crystalline powder, sometimes granular
Odor: Odorless or faint aromatic odor
Solubility: Soluble in water and alcohol,
pH (1% solution): Typically between 5 and 7
Melting Point: 163–168°C
Boiling Point: Decomposes before boiling
Vapor Pressure: Negligible at room temperature
Specific Gravity: 1.0–1.1 (water = 1)
Flash Point: Not applicable to solids
Partition Coefficient (n-octanol/water): Not measured directly, but moderate due to amphiphilic structure
Decomposition Temperature: Above 200°C (releases toxic fumes)

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions, sensitive to light and moisture
Reactivity: May react with strong oxidizing agents or acids
Hazardous Decomposition Products: Emits toxic fumes of hydrogen chloride, nitrogen oxides if heated to decomposition
Polymerization: Will not polymerize
Conditions to Avoid: Prolonged exposure to heat, open flames, acids, and oxidizers, avoid moisture ingress

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 410 mg/kg, Dermal LD50 (rabbit): 230 mg/kg—shows substantial toxicity based on amount and exposure route
Skin Corrosion/Irritation: Causes severe irritation or burns
Eye Damage/Irritation: Can cause blindness if not quickly and thoroughly rinsed
Inhalation: Inhalation of dust or aerosols may cause nose, throat, lung irritation
Chronic Effects: Repeated exposure may cause dermatitis, no strong evidence linking to reproductive toxicity or carcinogenicity yet documented
Sensitization: Not reported as a skin or respiratory sensitizer in most guidelines

Ecological Information

Ecotoxicity: Very toxic to aquatic organisms, can bioaccumulate in aquatic life, hazardous even at very low concentrations
Persistence and Degradability: Not readily biodegradable, remains in water and soil for extended periods
Mobility: Moderate in soil and water, significant run-off possible if released
Bioaccumulation: Has been shown to persist in aquatic organisms and the food chain
Other Adverse Effects: Disrupts bacterial and algae populations, alters aquatic ecosystem balance

Disposal Considerations

Waste Disposal: Dispose of as hazardous waste in accordance with local, regional, national, and international regulations, do not pour into waterways or drains, consider incineration at approved chemical disposal facilities
Contaminated Packaging: Empty residues must be triple-rinsed, containers disposed of as hazardous waste or according to governmental regulations

Transport Information

UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (Benzethonium chloride mixture)
Transport Hazard Classes: 6.1 (Toxic substances)
Packing Group: III
Labeling Requirements: Properly label packaging with toxic substance warnings and hazard pictograms
Special Precautions: Avoid cargo contact with food and feedstuffs, provide emergency spill and eye wash protocols in transit

Regulatory Information

Regulations: Registered with EPA as an active antimicrobial pesticide for some formulations, subject to workplace hazardous chemical management laws (OSHA, WHMIS, EU CLP/GHS)
Inventory Status: Listed in TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia), ENCS (Japan)
Restrictions: Not approved for use in food contact or ingestion in many regions, check specific local regulations
Labeling: Requires hazard pictograms, risk and safety phrases, precautionary statements as mandated by GHS/CLP and similar legal frameworks
SARA Title III (USA): Not listed as an extremely hazardous substance, but some reporting required for accidental releases