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Product Name: Benzathine Penicillin G
Chemical Family: Beta-lactam antibiotic
Synonyms: Benzathine penicillin, penicillin G benzathine
Chemical Formula: C48H56N6O8S2.C16H20N2
Intended Use: Antibacterial agent for treatment of infections caused by susceptible organisms
Manufacturer: [Company Information Inserted by Site]
Address: [Address Inserted by Site]
Emergency Phone Number: [Number Inserted by Site]
Contact Person: [Contact Details Inserted by Site]
CAS Number: 6130-64-9
Classification: Eye irritation, respiratory sensitizer, skin sensitizer
Hazard Symbols: GHS07, GHS08
Signal Word: Warning
Hazard Statements: May cause allergic reactions, respiratory symptoms, skin irritation, possible anaphylaxis on injection or inhalation
Routes of Exposure: Inhalation, skin contact, ingestion
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, wear suitable protective clothing
Acute Effects: Runny nose, sneezing, throat irritation, asthmatic symptoms
Chronic Effects: Repeated exposure increases risk of sensitization or developing allergies
Chemical Name: Benzathine Penicillin G
Concentration: ≥ 90% active ingredient
Other Components: Trace residuals (salts, moisture)
Impurities: Not expected to present significant health hazard at typical exposure levels
Molecular Weight: 909.12 g/mol
Inhalation: Move person to fresh air, support breathing, seek medical help if persistent cough, asthma-like symptoms, or breathing issues occur
Skin Contact: Remove contaminated clothing, rinse skin immediately with soap and water, call physician if irritation or persistent allergic reaction develops
Eye Contact: Rinse thoroughly with water for at least 15 minutes, keep eyelids apart, get medical advice if irritation remains
Ingestion: Rinse mouth, seek medical guidance, never induce vomiting unless ordered by a healthcare provider
Additional Notes: Individuals previously sensitized to beta-lactams may have severe reactions; always be alert for signs of anaphylaxis such as swelling, hives, difficulty breathing
Suitable Extinguishing Media: Use carbon dioxide, dry powder, foam, water spray
Unsuitable Media: Avoid high-pressure water streams on powder spills
Fire Hazards: Decomposition can release toxic fumes including nitrogen oxides and sulfur oxides
Protective Equipment: Self-contained breathing apparatus, full chemical protection suit, eye protection, gloves
Specific Hazards: Dust cloud can be ignited; flash fires possible
Special Procedures: Evacuate area, prevent fire water run-off from entering water courses or drains
Personal Precautions: Isolate spill area, restrict access, ventilate space, use protective equipment
Environmental Precautions: Prevent powder from entering soil, sewage, drains, or watercourses
Cleanup Methods: Collect with non-sparking tools, sweep or scoop into labeled containers, avoid generating dust
Decontamination: Wash remaining residue with mild detergent and water, dispose of cleaning solution safely
Reporting: Notify relevant authorities if release leads to environmental contamination
Handling Precautions: Wear gloves, goggles, lab coat; avoid inhaling dust or splashes; prevent contact with open cuts
Engineering Controls: Use local exhaust ventilation, handle in a chemical fume hood if available
Storage Temperature: Store between 2°C and 8°C, keep container tightly closed
Storage Location: Dry, cool, well-ventilated area, away from incompatible substances like oxidizers
Special Concerns: Protect from moisture, light exposure, and heat which can degrade product
Incompatibility: Strong acids, strong bases, oxidizing agents
Engineering Controls: Use process enclosures, local ventilation, or respiratory protection for dust
Eye Protection: Tight-fitting goggles or safety glasses
Skin Protection: Nitrile or latex gloves, protective clothing
Respiratory Protection: Dust mask or respirator (NIOSH-approved) if handling large quantities or insufficient ventilation
Exposure Limits: No established OSHA or ACGIH limits; minimize exposure as drug allergy risk is high
Workplace Hygiene: Wash hands after handling, do not eat or drink in working area, remove contaminated clothing promptly
Appearance: White to slightly off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (aqueous solution): Slightly acidic to neutral
Melting Point: Decomposes on heating above 200°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Slightly soluble in water, insoluble in alcohol
Vapor Pressure: Negligible
Relative Density: Not determined
Evaporation Rate: Not applicable
Partition Coefficient: Not determined
Viscosity: Not applicable
Flammability: Not highly flammable but combustible as a dust
Upper/Lower Explosion Limits: Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Degrades on heating with release of toxic fumes
Chemical Stability: Stable when kept dry, cool, and protected from light
Incompatible Materials: Strong acids, bases, oxidizers
Hazardous Decomposition Products: May release nitrogen oxides, sulfur oxides, and other toxic gases on heating or exposure to strong chemicals
Polymerization: Will not occur
Reactivity: May degrade in humid or hot conditions
Condition to Avoid: Moisture, light, elevated temperatures
Acute Toxicity: Low acute oral toxicity in mammals, but may cause severe allergic reaction even at low doses
Sensitization: Strong potential for skin and respiratory sensitization in exposed workers or healthcare providers
Repeated Exposure: May trigger asthma, eczema, other immune reactions
Carcinogenicity: Not listed by IARC, NTP, or OSHA as carcinogenic
Mutagenicity: Not expected to cause genetic damage based on available data
Reproductive Toxicity: No evidence of reproductive toxicity in animal studies
Target Organs: Skin, respiratory system, immune system
Medical Conditions Aggravated: Pre-existing allergies, asthma, skin disorders
Aquatic Toxicity: May pose risk to aquatic life, particularly algae and bacteria, due to antibiotic action
Persistence and Degradability: Partially biodegradable, potential for persistence in soil and water
Bioaccumulative Potential: Low
Mobility in Soil: Moderate—may leach under certain conditions, especially with rainfall
Environmental Precautions: Avoid large-scale release to waterways or sewage systems to limit impacts on microbial communities and prevent drug resistance selection
Product Disposal: Treat leftover material as pharmaceutical waste, incinerate in approved facility
Packaging Disposal: Decontaminate containers before recycling or follow local hazardous waste regulations
Sewage Disposal: Do not flush untreated product
Waste Handling: Lab personnel must wear gloves and protective gear, seal in labeled chemical waste bags, track for regulatory compliance
Regulatory Compliance: Follow national, regional, or local rules for hazardous or pharmaceutical waste, including notification or record-keeping where required
UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Label Requirements: None under international transport regulations
Transport Conditions: Keep product in original packaging, shield against humidity and high temperatures, avoid compressing containers during shipping
Special Precautions: Secure secondary containment if sent via air or sea freight to contain spills
OSHA Hazard: Regulated as a hazardous chemical within the meaning of 29 CFR 1910.1200
WHMIS Classification (Canada): D2B (Toxic Material causing other Toxic Effects)
EU Regulation: Listed in EINECS/ELINCS inventory; classification harmonized as sensitizer
TSCA Status (USA): Exempt as a drug or biologic
SARA Title III: Not listed as toxic chemical
Controlled Drug: Prescription-only medicine, subject to national and local prescription laws
Regional Requirements: Observe all relevant health, safety, and environmental regulations in your country
