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Product Name: Amprolium Hydrochloride
Chemical Formula: C14H19Cl2N3•HCl
CAS Number: 137-88-2
Recommended Use: Anticoccidial veterinary pharmaceutical, feed additive for poultry
Manufacturer/Supplier: Supplier details printed on package or invoice
Contact Phone (For Emergencies): Noted on manufacturer’s MSDS sheet
Synonyms: 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-picolinium chloride monohydrochloride
Relevant Identified Uses: Used mainly for poultry health management
Classification (GHS): Acute Toxicity Category 4 (Oral)
Label Elements: Exclamation mark, signal word: Warning
Hazard Statements: Harmful if swallowed, may cause mild irritation to eyes and skin
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Health Effects: May cause gastrointestinal disturbances such as nausea, vomiting, abdominal pain; possible skin or eye irritation on direct contact
Chronic Exposure Risks: Repeated exposure over time may affect animal health; specific effects in humans not fully established
Environment Hazards: Possible risk of water contamination and aquatic toxicity if product enters waterways
Chemical Name: Amprolium Hydrochloride
Concentration: Usually 100% (pure) or diluted depending on the formulation
Chemical Identity: C14H19Cl2N3•HCl
Impurities: Any significant impurities will be listed by manufacturer
Other Ingredients: In prepared mixtures, diluents and extenders are declared separately — always verify label for precise percentage breakdown
Inhalation: Remove to fresh air immediately. Seek medical attention if breathing becomes difficult.
Skin Contact: Rinse excess material with water. Wash skin thoroughly with soap and water. Remove contaminated clothing.
Eye Contact: Flush with plenty of clean water for 15 minutes. Contact physician if irritation persists.
Ingestion: Do not induce vomiting. Rinse mouth and drink moderate amount of water. Seek immediate medical attention.
Advice for Physicians: Treatment is symptomatic and supportive; monitor vital signs. No specific antidote known.
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Hazards from Combustion: Releases toxic fumes including nitrogen oxides, hydrochloric acid, and carbon oxides in fire
Personal Protective Equipment for Firefighters: Wear full protective clothing and self-contained breathing apparatus
Firefighting Procedures: Remove containers from fire area if safe; cool tanks or drums with water
Explosion Risk: Not classified as explosive, but excessive dust formation may present minor risk in enclosed spaces
Personal Precautions: Use appropriate PPE, avoid dust formation, ventilate area, restrict entry
Environmental Precautions: Prevent further leakage or spillage if safe to do so, stop material from entering drains, surface or ground water
Methods for Clean-up: Scoop up spilled powder with vacuum equipped with HEPA filter or sweep gently into waste container; avoid raising dust
Decontamination: Wash spill site with water after material pickup is complete
Disposal: See Disposal Considerations for instructions on managing waste
Safe Handling: Handle with proper protective equipment, avoid dust generation, avoid ingestion and contact with eyes or skin; maintain good hygiene
Storage Conditions: Keep container tightly closed in a dry, well-ventilated place; store away from incompatible materials such as oxidizing agents and strong acids
Temperature Recommendations: Store at room temperature; avoid extreme heat or cold
Incompatible Products: Keep away from oxidizers, strong acids or bases
Hygiene Practices: Wash hands thoroughly after use, do not eat or drink in work areas
Exposure Limits: No official occupational exposure limit established; minimize dust exposure
Engineering Controls: Use local exhaust or general room ventilation to keep air concentrations low
Personal Protective Equipment: Wear impervious gloves, lab coat, chemical safety goggles
Respiratory Protection: Use NIOSH/MSHA approved dust respirators if dust generation is likely
Other Protection: Use safety shower and eyewash facilities; keep work area free from clutter; change contaminated clothing
Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical scent
Solubility: Soluble in water
Boiling Point: Information not available
Melting Point: Around 169-170°C (decomposes)
Molecular Weight: 358.2 g/mol
pH (solution): 2.0–3.5 (1% in water)
Vapor Pressure: Not applicable
Density: Information not provided by standard suppliers
Chemical Stability: Stable under recommended storage conditions
Reactivity: No dangerous reactions known under normal conditions
Incompatible Materials: Strong oxidizers, acids, bases, some metal salts
Hazardous Decomposition Products: Releases toxic fumes under fire conditions, including nitrogen oxides and hydrochloric acid
Hazardous Polymerization: Not known to occur
Likely Routes of Exposure: Skin and eye contact, inhalation, ingestion
Acute Toxicity: LD50 (oral, rat) reported at approximately 3800 mg/kg
Irritation: May cause mild irritation to eyes, skin and mucous membranes
Chronic Toxicity: Chronic exposure to large doses showed neurological symptoms in test animals
Carcinogenicity: Not listed by IARC, NTP or OSHA
Other Effects: Watch for signs of hypersensitivity in some individuals or animals
Ecotoxicity: Can affect aquatic organisms; limited biodegradability reported
Persistence and Degradability: Partial persistence in environment, breaks down slowly
Bioaccumulation Potential: Low; not expected to concentrate significantly in organisms
Mobility in Soil: Mobility depends on soil characteristics; not highly mobile but residuals may reach water systems
Other Adverse Effects: Care needed to prevent large-scale releases into the environment
Safe Disposal Methods: Dispose of spill and waste in accordance with local, regional, national, and international regulations
Disposal of Packaging: Triple rinse, puncture, and send to approved drum recycler or hazardous waste facility
Incineration: Incinerate wastes at high-temperature, authorized facilities if permitted
Do Not: Discharge waste product into drains, surface water, or soil
UN Number: Not assigned (non-hazardous for transport under most regulations)
Proper Shipping Name: No specific designation required
Transport Hazard Class: Not classified as hazardous
Packing Group: Not applicable
Label Requirements: No special labels required, unless mixed with other hazardous substances
Additional Information: Keep container well-sealed, dry, protect from physical damage during transit
US Federal Regulations: Not listed as a controlled substance, but subject to state-specific regulations for feed additives
OSHA Compliance: Not specifically regulated, general workplace safety rules apply
EU Regulation: EC No. 1907/2006 (REACH) compliance recommended
Other International Regulations: May require notification to authorities depending on country, especially for use in food production
Inventory Status: Listed or approved in major chemical inventories like TSCA, EINECS/ELINCS
Labelling: Must clearly state composition, hazards, and manufacturer details as per local law
