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Product Name: Ampicillin Trihydrate
Chemical Formula: C16H19N3O4S·3H2O
Synonyms: D(-)-α-Aminobenzylpenicillin trihydrate, Penbritin
CAS Number: 7177-48-2
Recommended Use: Antibiotic for pharmaceutical industry and laboratory use
Manufacturer Details: Not specified here, check label
Emergency Contact: Poison Control or Local Health and Safety Officer
GHS Classification: Sensitization, Skin (Category 1); Sensitization, Respiratory (Category 1); Reproductive toxicity (Category 2)
Label Elements: Warning; pictograms for health hazard and exclamation mark
Hazard Statements: May cause allergic skin reaction; May cause allergy or asthma symptoms or breathing difficulties if inhaled; Suspected of damaging fertility or the unborn child
Precautionary Statements: Wear protective gloves and use a respirator
Chemical Name: Ampicillin Trihydrate
Content: ≥95% by weight
CAS Number: 7177-48-2
Impurities: Minimal, varies by manufacturer
Eye Contact: Rinse with water for several minutes; seek medical attention if discomfort persists
Skin Contact: Immediately wash with soap and water; take off contaminated clothing; see doctor for rash or irritation
Inhalation: Move out of contaminated area; provide fresh air; get medical advice for breathing problems
Ingestion: Rinse mouth; seek medical help if feeling unwell or symptoms develop
Acute Symptoms: Allergic reactions, difficulty breathing, skin sensitization
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam
Specific Hazards: May release toxic fumes of oxides of nitrogen, sulfur oxides, carbon oxides
Protective Equipment for Firefighters: Use full protective gear and self-contained breathing apparatus
Special Precautions: Avoid inhaling combustion products
Personal Precautions: Wear gloves, mask, safety goggles, and lab coat
Environmental Precautions: Prevent spillage from entering drains or surface water
Cleanup Methods: Sweep up solid or use absorbent for liquid spills; collect in labeled containers for disposal; ventilate area
Disposal: Follow local regulations
Handling: Work with proper ventilation; keep away from skin, eyes, and clothing; avoid dust generation
Storage Conditions: Store in a cool, dry place; keep container tightly closed; avoid direct sunlight and moisture
Incompatible Materials: Strong oxidizers, acids, alkalis
Engineering Controls: Use fume hood or ventilation system
Respiratory Protection: NIOSH-approved respirator if dust may be generated
Skin Protection: Chemical-resistant gloves, long sleeves
Eye Protection: Chemical safety goggles
Additional Protection: Avoid direct contact; use personal hygiene and wash hands thoroughly after handling
Appearance: White to off-white crystalline powder
Odor: Faint, characteristic
Molecular Weight: 403.45 g/mol (trihydrate)
Melting Point: Decomposes above 200°C
Solubility: Freely soluble in water
pH: 3.5–5.5 in aqueous solution
Boiling Point: Not applicable (decomposes before boiling)
Flammability: Not highly flammable, but combustible
Chemical Stability: Stable under recommended storage; sensitive to heat and moisture
Reactivity: Reacts with strong acids, bases, and oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon oxides
Polymerization: Will not occur
Acute Toxicity: LD50 (Oral, Rat): >5000 mg/kg
Routes of Exposure: Inhalation, skin/eye contact, ingestion
Symptoms: Allergic reactions, rash, respiratory distress, gastrointestinal upset, rarely anaphylaxis
Chronic Effects: Can cause hypersensitivity in exposed individuals
Mutagenicity/Carcinogenicity: No strong evidence of carcinogenicity
Reproductive Toxicity: Animal studies suggest some risk; consult recent literature
Ecotoxicity: Harmful to aquatic life; may cause long-term effects
Aquatic Toxicity: Data not completely available, precaution recommended
Persistence and Degradability: Not readily biodegradable; can persist in environment
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Likely to move into groundwater, caution near water sources
Waste Disposal Methods: Dispose as hazardous waste according to local, state, and federal requirements
Container Disposal: Triple rinse and discard in accordance with regulations
Avoid: Disposal in household garbage, sinks, or conventional landfill
UN Number: Not regulated for transport
Transport Hazard Class: Non-hazardous for air, road, or sea shipment under normal conditions
Packing Group: Not applicable
Special Precautions: Protect from physical damage, keep dry during transport
OSHA Status: Regulated as hazardous if in industrial workplace
EPCRA Section 302/304: Not listed
SARA Title III Section 313: Not subject to reporting
International Inventories: Listed in relevant chemical inventories such as TSCA, EINECS
Safety Assessment: Consult local regulatory body for latest compliance information
