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Product Name: Aminopyrine
Chemical Formula: C11H13N3O
Synonyms: 4-Dimethylaminoantipyrine, Amidopyrine
CAS Number: 58-15-1
Recommended Use: Laboratory research, chemical analysis, pharmaceutical testing
Manufacturer Details: Sourced from chemical supply companies specialized in laboratory and industrial reagents
Emergency Contact: Emergency numbers listed by national poison control centers and workplace safety officers
Impurities and Stabilizing Additives: Typically none for analytical grade; consult supplier COA for trace impurities
GHS Classification: Acute toxicity, Carcinogenicity, Specific organ toxicity
Hazard Statements: Harmful if swallowed, Inhalation may cause symptoms related to methemoglobinemia, Possible carcinogen
Pictogram: Exclamation mark, Health hazard
Signal Word: Warning
Precautionary Statements: Avoid breathing dust or fumes, Wash hands thoroughly after handling, Wear protective gloves and eye/face protection
Chemical Name: Aminopyrine
Concentration: Pure, typically >98%, remaining content attributed to trace moisture
Other Components: Not intentionally present; check COA for potential impurities
Inhalation: Remove the exposed individual to fresh air, watch for symptoms of dizziness, cyanosis, or headache, seek medical attention quickly for breathing difficulties
Skin Contact: Wash affected area thoroughly with soap and water, remove contaminated clothing, consult medical help if irritation persists
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes, keep eyelids open, get medical assistance if discomfort remains
Ingestion: Rinse mouth, do not induce vomiting, get immediate medical advice to handle the risk of methemoglobinemia
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Special Hazards: Toxic gases including nitrogen oxides and carbon monoxide can form during combustion
Protective Equipment: Firefighters must wear self-contained breathing apparatus and chemical-resistant suits
Specific Actions: Remove containers from the fire zone if safe, cool surrounding containers, avoid inhaling fumes
Personal Protection: Use protective gloves, goggles, laboratory coat; avoid breathing dust
Spill Cleanup: Sweep up carefully to avoid dust creation, and transfer to a sealed waste container
Environmental Precautions: Prevent powder from entering drains, sewers, or waterways
Decontamination: Wash all surfaces with water and detergent after cleanup
Safe Handling: Handle in a well-ventilated area or chemical fume hood; minimize dust production
Hygiene Measures: Avoid eating, drinking, or smoking during handling; always wash hands after use
Storage Conditions: Store in tightly sealed containers, away from light, moisture, and incompatible chemicals like strong oxidizers
Temperature Recommendations: Keep at room temperature, do not freeze or expose to excessive heat
Exposure Limits: No established occupational exposure limits; reduce exposure to lowest possible
Engineering Controls: Use chemical fume hoods, local exhaust ventilation, and enclosed processes
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or rubber), safety goggles, lab coats; PPE must match workplace risk assessment
Respiratory Protection: If airborne dust is present, use a NIOSH-approved respirator mask (P100 or equivalent)
Monitoring Procedures: Employers should check air quality and protect staff with personal exposure monitoring when large quantities are handled
Appearance: White to pale yellow crystalline powder
Odor: Odorless
Melting Point: 110–113°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, chloroform
pH: Not applicable in solid form
Vapor Pressure: Negligible under standard conditions
Relative Density: 1.2 (water = 1)
Partition Coefficient: Not provided in typical supplier documentation
Viscosity: Not applicable for solids
Chemical Stability: Stable under recommended storage conditions; degrade under strong UV light or heat
Reactivity: May react with oxidizers and strong acids, risk of hazardous decomposition products
Conditions to Avoid: Exposure to high temperatures, light, and moisture accelerates breakdown
Incompatible Materials: Avoid mixing with strong acids or oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, nitrogen oxides, other toxic fumes upon burning or heating
Acute Effects: Ingestion causes nausea, vomiting, and risk of methemoglobinemia which reduces blood oxygen carrying ability
Chronic Effects: Long-term or repeated exposure may damage the liver and bone marrow, linked to agranulocytosis
Carcinogenicity: Possibly carcinogenic to humans, not a known carcinogen in all regulatory lists
Exposure Routes: Skin contact, inhalation, ingestion, eye contact
Target Organs: Blood, liver, bone marrow
Symptoms of Overexposure: Cyanosis, headache, weakness, jaundice, rapid heart rate
Aquatic Toxicity: Harmful to fish and aquatic organisms due to potential for bioaccumulation
Mobility in Soil: May migrate in moist soils, risk to groundwater if released in large quantities
Biodegradability: Exact figures not published for aminopyrine, assumed moderate to low persistence in the environment
Impact on Sewage Treatment: Toxic to beneficial bacteria in wastewater plants
Avoid Release: Never discharge directly into drains, sewers, or surface waters
Waste Handling: Collect unused material and contaminated packaging as hazardous chemical waste
Recommended Disposal Methods: Send to licensed chemical disposal contractors for incineration or secure landfill
Avoid: Do not wash into sinks or regular trash lines, avoid open burning
Regulations: Follow local, state, and national hazardous waste disposal requirements
UN Number: Not assigned; some suppliers mark as non-regulated for small laboratory quantities
Transport Class: Not classified as dangerous for road, air, or maritime transport at common research quantities
Packing Group: Generally not listed, because of trade and academic use in minimal risk settings
Special Precautions: Seal containers tightly, pack to prevent leaks or spillage, mark as chemical for laboratory use during shipment
Handle Spills: In transit, spilled material handled under hazmat procedures by trained personnel
Regulation Status: Not controlled under major international conventions like the U.S. TSCA, EU REACH, or IATA dangerous goods codes for research use
OSHA Status: No specific standard; governed by general chemical safety standards
Other National Regulations: Some countries have placed restrictions due to hematological risks
Labeling Requirements: Chemical name, hazard warnings, supplier identification, batch number maintained for all packaging
Recordkeeping: Employers required by law to keep updated MSDS sheets and training logs available for all staff handling hazardous chemicals
