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Product Name: Aminomethylbenzoic Acid
Chemical Name: 4-(Aminomethyl)benzoic acid
CAS Number: 56-91-7
Synonyms: AMBA; p-Aminomethylbenzoic acid
Molecular Formula: C8H9NO2
Molecular Weight: 151.16 g/mol
Supplier Identification: Manufacturer details usually appear here, with an emergency phone number and address for quick reference.
Recommended Use: Used as a hemostatic agent in pharmaceutical applications, research, and sometimes industrial production.
Restrictions: Not advised for uses outside pharmaceutically regulated and authorized environments.
Classification (GHS): Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3, respiratory system)
Signal Word: Warning
Hazard Statements: Causes skin irritation, serious eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection
Label Elements: Exclamation mark symbol, hazard pictograms required by GHS regulations
Hazard Routes of Entry: Inhalation, ingestion, skin, and eye contact
Prolonged Exposure Risks: Possibility of persistent irritation to the mucous membranes, throat, and lungs.
Chemical Identity: 4-(Aminomethyl)benzoic acid
Purity: >98% (commercial grade)
Impurities: Expected trace levels of related aromatic acids, not usually present above 1%.
CAS Number: 56-91-7
Relevant Ingredients: This product contains only active ingredient with no additional hazardous additives in standard laboratory supply.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, making sure to hold eyelids apart. Seek medical attention promptly if irritation persists.
Skin Contact: Wash skin thoroughly with soap and water. Remove contaminated clothing and shoes. If signs of irritation or rash develop, call a physician.
Inhalation: Move person to fresh air and keep comfortable for breathing. If cough, wheezing, or shortness of breath develops, seek immediate medical advice.
Ingestion: Rinse mouth thoroughly with water. Do not induce vomiting. Consult a physician if victim feels unwell or shows symptoms.
Most Important Symptoms: Redness, irritation, respiratory difficulty, nausea, headache may occur in overexposed individuals.
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide.
Specific Hazards: Fine dust in suspension can ignite or explode; product decomposes, releasing toxic fumes including nitrogen oxides and carbon monoxide if involved in a fire.
Protective Equipment: Wear full protective gear including self-contained breathing apparatus, fire-resistant suit, gloves, and face shield.
Special Precautions: Keep unnecessary personnel away from the fire site, and avoid inhalation of hazardous combustion products.
Personal Protection: Equipment such as NIOSH-approved respirator, chemical-resistant gloves, goggles, and protective clothing should be worn.
Environmental Precautions: Prevent entry into sewers, soil, and waterways. Limit environmental dispersion promptly.
Clean-up Methods: Carefully sweep or use HEPA vacuum to collect spilled material; avoid creating airborne dust, transfer into suitable, labeled waste containers for disposal.
Emergency Procedures: Evacuate area, ventilate, and monitor for dust; call specialist support if spill is beyond safe handling limits.
Precautions for Safe Handling: Use controls that minimize dust generation and accumulation, conduct operations in well-ventilated area. Keep containers closed when not in use. Practice routine hygiene—wash hands before breaks, after use, and before meals; do not eat, drink, or smoke around the chemical. Avoid skin, eye, and respiratory exposure by following recommended precautions.
Conditions for Safe Storage: Store in original, well-sealed containers away from light, moisture, and incompatible products such as strong oxidizers. Recommended temperature: room temperature (15-25°C) unless otherwise directed by supplier. Keep in areas with secondary containment for solid chemicals, ensure signage for hazardous material storage.
Exposure Limits: Occupational Exposure Limits (OELs) not established for aminomethylbenzoic acid; use engineering controls and best practice to minimize exposure.
Engineering Controls: Work in well-ventilated area, ideally with chemical fume hood. Local exhaust recommended for dust-generating operations.
Personal Protective Equipment (PPE): NIOSH-approved respirators for dust/mist, safety goggles or face shield, chemical-resistant gloves (nitrile or neoprene), lab coat or apron, and closed-toe shoes recommended.
Industrial Hygiene: Regular review of safety measures, medical surveillance for frequent users, safe disposal of contaminated clothing.
Appearance: White to off-white crystalline powder
Odor: Odorless to faintly aromatic
pH (1% solution): 3.0 – 4.0
Melting Point: 172 – 175°C
Boiling Point: Not determined; decomposes before boiling
Solubility: Slightly soluble in water, more soluble in hot water, very slightly soluble in alcohols and acetone
Vapor Pressure: Negligible at room temperature
Relative Density: Approx. 1.3 g/cm³
Partition Coefficient (n-octanol/water): Not available
Flash Point: Not applicable (solid)
Evaporation Rate: Not relevant for solid material
Decomposition Temperature: >175°C
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: May react with strong oxidizing agents or bases, producing hazardous byproducts.
Hazardous Reactions: None expected under normal work conditions. Avoid direct heat, sunlight, and strong acids or bases.
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide can produce under fire or thermal decomposition.
Polymerization: No indication of hazardous polymerization during standard storage.
Acute Toxicity: Not classified as acutely toxic via ingestion, inhalation, or skin contact in small quantities, but may cause discomfort or mild health effects.
Skin Corrosion/Irritation: Documented cases of mild to moderate irritation with repeated contact; prolonged or repeated exposure may worsen reaction.
Serious Eye Damage/Irritation: Can lead to serious irritation, tearing, persistent redness.
Respiratory Sensitization: Inhalation of dust causes throat, nose, and lung irritation; coughing and respiratory discomfort may develop with significant exposures.
Chronic Toxicity: No conclusive evidence for carcinogenicity, reproductive toxicity, or mutagenicity in validated animal studies using aminomethylbenzoic acid.
Symptoms of Overexposure: Redness, itching, headache, cough, dizziness, nausea.
Eco-toxicity: There are limited data but low toxicity is expected for aquatic and terrestrial species at typical concentrations; high concentrations have not been studied in detail.
Persistence and Degradability: Expected to be only slowly biodegradable, may persist in soil or water when disposed in large amounts.
Bioaccumulation Potential: Bioaccumulation unlikely based on structure and low fat solubility.
Mobility in Soil: Slight; compound may bind to organic matter due to aromatic structure.
Other Adverse Effects: Spills or dumping in freshwater systems should be avoided, use available data to follow local guidelines for minimal environmental impact.
Waste Treatment Methods: Material disposal must comply with local, regional, and national regulations; incineration in controlled facility recommended for large amounts, small laboratory quantities can be diluted and treated as hazardous chemical waste.
Contaminated Packaging: Rinse empty containers thoroughly; dispose of as hazardous waste or recycle according to chemical safety standards.
Avoid Release to Environment: Prevent product and solution runoff into natural water systems, storm drains, and public sewage.
UN Number: Not classified as hazardous for transport under most international transport regulations.
Proper Shipping Name: Aminomethylbenzoic Acid (For identification and declaration purposes)
Transport Hazard Class: Not dangerous under ADR, IMDG, IATA regulations
Packing Group: Not assigned
Special Precautions: Keep tightly closed, use containers that prevent leaks and contamination during movement, avoid contact with foodstuffs or pharmaceuticals in transit.
OSHA Status: Not regulated as a hazardous chemical under OSHA standard 29 CFR 1910.1200
TSCA Inventory: Listed
EU Classification: Not classified as dangerous under EC Directive 1272/2008
DSL/NDSL (Canada): Listed
Hazard Labelling: Local workplace labeling requirements apply for emergency response, storage, and handling.
SARA Title III: Not listed under SARA Sections 302, 304, 313
California Proposition 65: Substance not listed or expected to be listed
Other Relevant Laws: Follow community workplace chemical safety, reporting, and exposure restrictions to meet current regulations.
