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Product Name: Acriflavine Hydrochloride
Synonyms: 3,6-Diamino-10-methylacridinium chloride, Acriflavinium chloride
CAS Number: 8063-24-9
EC Number: 617-121-5
Molecular Formula: C14H14ClN3
Molecular Weight: 259.7 g/mol
Recommended Use: Laboratory chemical, antimicrobial agent, dye
Supplier Information: Check packaging for distributor details and contact emergency services if direct supplier is unavailable
Classification: Eye irritation (Category 2), Skin irritation (Category 2), Acute aquatic toxicity (Category 1), Carcinogenicity (Category 2)
Label Elements: Pictograms for hazard; warnings for skin and eye contact
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, suspected of causing cancer, very toxic to aquatic life
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, wear protective gloves, use eye or face protection, dispose of contents/container according to regulations
Chemical Identity: Acriflavine Hydrochloride
Purity: Typically greater than 95% active ingredient
Impurities: Trace amounts of water or other related compounds
Concentration: 100% unless otherwise specified by supplier
Additives: None detected in certified pure laboratory samples
General Advice: Remove contaminated clothing, call a physician if symptoms develop
Inhalation: Move person to fresh air, keep at rest, seek medical attention if breathing becomes difficult
Skin Contact: Immediately wash skin with soap and plenty of water, seek medical advice if irritation persists
Eye Contact: Flush eyes with copious amounts of water for at least 15 minutes, make sure to remove contact lenses, call a doctor promptly
Ingestion: Rinse mouth, call poison control or seek medical aid, do not induce vomiting unless instructed by medical personnel
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide depending on the type of fire
Specific Hazards from Fire: May release irritating or toxic fumes such as nitrogen oxides, hydrogen chloride, carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Special Precautions: Cool exposed containers with water spray to prevent rupture
Combustion Products: Potentially hazardous gases including acrid smoke and nitrogen derivatives
Personal Precautions: Evacuate area, avoid contact with skin and eyes, use personal protective equipment such as gloves and goggles
Environmental Precautions: Prevent further leakage or spillage if safe to do so, stop release into drains, surface/groundwater
Methods for Clean-Up: Scoop up spilled material using non-sparking tools, sweep up without creating dust, place in a properly labeled container for disposal
Decontamination: Wash area with plenty of water, ventilate enclosed spaces, monitor air quality as needed
Handling: Avoid inhalation of dust, avoid contact with skin, eyes, and clothing, handle in a well-ventilated area, keep container tightly closed
Personal Hygiene: Wash hands thoroughly after handling, do not eat, drink or smoke in working area
Storage: Store in a cool, dry, well-ventilated area away from sunlight, keep away from incompatible substances such as strong oxidizers, acids, or bases
Container: Use properly labeled, tightly sealed containers to prevent moisture and air ingress
Exposure Limits: No established occupational exposure limits for acriflavine hydrochloride
Engineering Controls: Use fume hood or adequate ventilation to minimize airborne concentration, employ local exhaust
Personal Protective Equipment: Protective gloves (nitrile, neoprene), chemical safety goggles, lab coats, protective footwear
Respiratory Protection: If risk of airborne dust or aerosol exists, wear appropriate NIOSH/MSHA-approved particulate respirator
Work/Hygienic Practices: Remove contaminated clothing and wash before reuse, dispose of gloves after use, always follow standard laboratory safety procedures
Appearance: Dark orange to brown powder
Odor: Odorless or very faint chemical scent
pH: 4.5 - 5.5 (1% solution in water)
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Flash Point: Not determined
Solubility: Soluble in water (forms bright yellow-green solution), slightly soluble in alcohol
Vapor Pressure: Not determined
Relative Density: 1.15 - 1.25 g/cm³
Partition Coefficient (log Kow): Not determined
Viscosity: Not applicable
Decomposition Temperature: Above 140°C
Evaporation Rate: Not applicable
Chemical Stability: Stable under normal conditions of use and storage
Conditions to Avoid: Exposure to strong sunlight, moisture, elevated temperatures
Incompatible Materials: Strong oxidizing agents, acids, strong bases
Hazardous Decomposition Products: May generate nitrogen oxides, hydrogen chloride, carbon oxides upon thermal decomposition
Polymerization: Will not occur
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin
Chronic Effects: Prolonged or repeated exposure can lead to skin sensitization and mutagenic effects in mammalian cells
Carcinogenicity: Classified as a possible carcinogen based on animal data and some in-vitro studies
Routes of Exposure: Eyes, skin, inhalation, ingestion
Symptoms of Exposure: Irritation, redness, pain in contact areas, possible systemic effects if absorbed
Mutagenicity: Evidence of mutagenic potential in laboratory tests
Ecotoxicity: Very toxic to aquatic organisms, risk of long-term adverse effects in aquatic environments
Persistence and Degradability: Not readily biodegradable, may remain in the environment for extended periods
Bioaccumulative Potential: Low potential for bioaccumulation, limited available data
Mobility in Soil: Moderately mobile, especially in moist or wet environments
Other Adverse Effects: Disrupts aquatic microbial activity, impacts growth of aquatic plants and animals
Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber complying with local regulations
Contaminated Packaging: Dispose of in accordance with governmental regulations, clean containers before recycling if possible
Special Precautions: Do not discharge into drains or environment, avoid scattering dust
Additional Details: Use licensed waste disposal contractors familiar with handling hazardous laboratory or chemical waste
UN Number: Not regulated as a dangerous good under most transport regulations (IATA, ADR, IMDG)
Proper Shipping Name: Acriflavine Hydrochloride, or chemical, non-hazardous for transport
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Environmental Hazards: Marine pollutant if large quantities are released
Special Precautions for User: Keep container tightly closed, avoid transport with food or feedstuff, comply with local transport regulations
US Regulations: Not listed as a hazardous substance under CERCLA, SARA 302, SARA 313; subject to workplace safety standards set by OSHA, hazard communication may be required
EU Regulations: Subject to classification and labeling according to Regulation (EC) No 1272/2008 (CLP), not included on the REACH Authorisation List
Canada: Listed on DSL/NDSL; workplace controls necessary under WHMIS
Other International Regulations: Subject to chemical safety reporting in Japan, Australia, and South Korea under separate country-specific rules
Labelling Requirements: Requires GHS label with appropriate hazard symbols and statements
