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Product Name: Acetyl Ketene, Stabilized
Chemical Formula: C4H4O2
CAS Number: 674-82-8
Synonyms: Ketene, acetyl-; Ethenone, methyl-; 1-propanone, 1-ethenyl-, stabilized
Recommended Uses: Industrial intermediate, laboratory chemical
Supplier Details: Chemical manufacturers and suppliers include addresses and emergency phone lines for immediate response
Emergency Contact: Medical toxicology centers and local authorities handle prompt support for exposure or leaks
GHS Classification: Acute toxicity (Oral, Inhalation, Dermal), Eye Irritation, Corrosive to Respiratory Tract
Hazard Pictograms: Skull and crossbones, Corrosive, Exclamation mark
Signal Word: Danger
Hazard Statements: Fatal if inhaled, Harmful if swallowed or in contact with skin, Causes severe skin burns and serious eye damage, Vapors may trigger respiratory problems and long-lasting effects on organs exposed to repeated or high doses
Precautionary Measures: Use personal protection, Do not breathe fumes, Seek medical advice if symptoms develop after handling the substance
Chemical: Acetyl Ketene, Stabilized
Concentration: Minimum 95%
Stabilizer: Typically contains a stabilizing agent (proprietary, 5%) to enhance shelf life and reduce hazardous decomposition
Impurities: Trace organics from manufacturing process
CAS Number: 674-82-8 (Acetyl Ketene)
Potential Additives: Stabilizing agents or inhibitors depend on supplier’s formulation and storage needs
Inhalation: Remove victim from exposure area to fresh air immediately, Keep patient warm, If breathing problems persist, provide oxygen, Seek urgent medical attention
Skin Contact: Remove contaminated clothing, Flush skin with plenty of running water for at least 15 minutes, Seek medical support for skin burns or irritation
Eye Contact: Rinse cautiously with water for several minutes, Remove contact lenses if present, Continue rinsing eyes and consult ophthalmologist
Ingestion: Rinse mouth with water, Do not induce vomiting, Seek immediate medical help, Symptoms might include nausea, abdominal pain, or chemical burns
General Advice: Emergency showers and eyewash stations near workspaces, Trained personnel on hand at all times
Suitable Extinguishing Media: Dry chemical, Carbon dioxide, Foam, Avoid water under pressure as it can spread fire or react with the material
Specific Hazards: Highly flammable liquid and vapor, Decomposes under heat to form toxic gases like carbon monoxide and carbon dioxide, Flashpoint can drop in the presence of other chemicals
Special Protective Equipment: Firefighters use self-contained breathing apparatus and full protective suit, Chemical-resistant gloves and boots recommendable
Advice for Firefighters: Move containers away from fire if safe, Cool containers with water spray to prevent explosion, Dike runoff to avoid environmental contamination
Personal Precautions: Evacuate area, Use full PPE (respirator, gloves, goggles, suit), Avoid contact with skin, eyes, and clothing
Environmental Precautions: Prevent spill from entering waterways, soil, or drains, Notify authorities in case of large discharge
Containment Techniques: Use non-sparking tools, Cover spill with inert absorbent (sand, vermiculite), Collect waste in chemical-safe container
Clean-up Methods: Ventilate area, Wash site after material pickup is complete, Dispose residues according to hazardous waste guidelines
Safe Handling Practices: Handle only in fume hoods or well-ventilated areas, Avoid aerosol or vapor generation, Do not eat, drink, or smoke while working with chemical
Storage Requirements: Store in original, airtight, clearly labeled containers, Keep cool (2-8°C) and dry, Separate from oxidizers, acids, and incompatible chemicals, Avoid light and extreme temperatures
Special Storage Conditions: Regularly monitor storage area for leaks, Use corrosion-resistant shelving, Clearly post hazard signs, Install spill containment systems for liquid containers
Occupational Exposure Limits: Manufacturer recommended limit typically 0.1 ppm (TWA), National regulations may differ, No established OSHA or ACGIH standard as of last update
Engineering Controls: Chemical fume hood, Explosion-proof ventilation system, Closed transfer systems
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or neoprene), Full-face respirator (NIOSH-approved), Lab coat and flame-retardant coveralls, Safety goggles or face shield, Chemical-resistant shoes or boots
Hygiene Measures: Wash hands thoroughly before breaks or after handling, Remove contaminated clothing at once, Regular safety audits and PPE training for workers
Appearance: Colorless, volatile liquid, may appear slightly yellow due to stabilizer
Odor: Acrid, pungent odor reminiscent of acetic acid and ketones
pH: Not applicable for neat liquid
Melting Point: -15°C
Boiling Point: 44°C (rapid evaporation at room temperature possible)
Flash Point: Below 0°C
Evaporation Rate: Rapid, especially in open air
Vapor Pressure: High at room temperature, requires tightly sealed bottles
Density: About 0.96 g/cm³
Solubility: Slightly soluble in water, soluble in organic solvents (ether, acetone)
Partition Coefficient: Log Kow estimated at 0.8-1.2
Viscosity: Low, flows easily
Chemical Stability: Stable in presence of added stabilizers when stored at recommended conditions, Becomes unstable if exposed to heat, light or ignition sources
Reactivity: Reacts violently with acids, bases, strong oxidizers
Hazardous Decomposition Products: Ketene gas, carbon monoxide, carbon dioxide under fire or heat exposure
Conditions to Avoid: Humidity, high heat, UV light, friction or shock, Mixing with incompatible chemicals
Incompatible Materials: Strong acids, strong bases, oxidizers, reducing agents and some plastics
Polymerization: May occur if stabilizer runs out or under improper storage, Releases heat and gas rapidly
Acute Toxicity: LC50 (rat, inh) < 10 ppm/4h, LD50 (rat, oral) 40 mg/kg, Low dermal absorption but skin burns reported
Corrosivity: Potent corrosive action on skin, eyes, and upper respiratory system; effects include ulceration, vision loss, blistering, scarring
Chronic Exposure: Repeated low-level inhalation irritates lungs and may cause asthma-like symptoms, Prolonged absorption linked to liver and kidney effects in animal studies
Sensitization: Limited evidence but recurring contact could lead to allergic skin reaction
Carcinogenicity/Mutagenicity: No clear human data as of last reviews, Animal tests suggest DNA effects with long-term, high-level exposure
Other Effects: Headache, confusion, chemical pneumonitis possible after large exposure
Ecotoxicity: Highly toxic to aquatic life (fish, invertebrates), Rapid breakdown but acute effects on exposed organisms
Persistence and Degradability: Decomposes in air and water, Half-life estimated at less than 24 hours in sunlight or water
Bioaccumulation Potential: Moderate, Data on persistent residues still under review
Mobility: Volatile, Can migrate through soil rapidly, Vapor phase movement in air possible
Other Adverse Effects: Local spills may cause short-term environmental disruption, Use containment and emergency planning to reduce contamination chances
Waste Treatment Methods: Incineration at licensed facility, Chemical neutralization with extreme care only by trained personnel
Packaging Disposal: Rinse containers with suitable solvent, Dispose of containers as hazardous waste according to local rules
Contaminated Materials: Burn under controlled conditions or use authorized hazardous waste disposal service, Record all waste movements for compliance
Other Notes: Never dispose in general waste, sewer, or open ground, Engage professional handlers for large quantities
UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (Acetyl Ketene, Stabilized)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: I (high danger)
Labels: Flammable liquid, Toxic, Corrosive as per international regulations
Special Precautions: Use non-sparking, sealed containers, Ship only with regulatory paperwork, Avoid transport with incompatible cargoes, Report accidental leaks in transit at once
OSHA Hazard Classification: Regulated as acute toxic, flammable and corrosive substance
SARA (Title III): Subject to reporting under Sections 302, 304, 313 (acute health, fire, reactivity hazards)
TSCA Status: Listed
Other US Regulations: State right-to-know lists (CA, NJ, PA), Workplace monitoring required
International Listings: Registered under REACH (EU), Included in various country-specific hazard inventories
Transport Regulations: DOT, IMDG, IATA and ADR guidance applies for overland, air, and sea shipping
