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Product Name: Ipriflavone, 7-Methoxyisoflavone
Synonyms: 7-Isoflavonoxyisoflavone, Ipriflavone
Chemical Formula: C18H16O3
CAS Number: 446-72-0
Recommended Use: Researchers use ipriflavone in laboratories for bone metabolism studies and related pharmaceutical research.
Manufacturer/Supplier: [Contact details according to actual supplier]
Emergency Contact: [Insert local/national emergency phone number]
Hazard Classification: Not classified as hazardous according to GHS but can cause irritation if inhaled or exposed to skin and eyes.
Signal Word: Warning
Hazard Statements: May cause mild skin irritation, eye irritation. Dust inhalation may be irritating to respiratory tract.
Precautionary Statements: Avoid breathing dust. Wear protective gloves and safety glasses. Wash hands thoroughly after handling.
GHS Label: Not required, but general chemical caution applies.
Potential Health Effects: Long-term repeated exposure may affect liver function or bone metabolism based on animal studies. Seek out health professional advice for occupational exposure above recommended limits.
Chemical Name: Ipriflavone
Concentration: ≥98% pure
CAS Number: 446-72-0
Impurities/Additives: None known in standard preparations. Trace impurities may arise during synthesis.
Molecular Weight: 280.32 g/mol
Other Ingredients: No binding agents, diluents or other chemical additives included unless specified by supplier.
Inhalation: Move to fresh air, keep at rest in a comfortable position, seek medical attention if symptoms persist. Clear nasal passages if safe.
Skin Contact: Remove contaminated clothing. Wash skin using mild soap and water. Seek medical advice if irritation persists or discomfort appears.
Eye Contact: Rinse gently with plenty of water for at least 15 minutes, occasionally lifting upper and lower eyelids. Remove contacts if easy. If symptoms persist, get medical help.
Ingestion: Rinse mouth, give water if conscious. Never give anything by mouth to an unconscious person. Seek medical advice if large amounts are ingested.
Other Advice: Show the safety data sheet to the doctor in attendance. Treat based on symptoms.
Suitable Extinguishing Media: Use dry chemical powder, foam, carbon dioxide, or water spray for small fires.
Unsuitable Media: Do not use a water jet directly on the burning mass; risk of chemical runoff.
Specific Hazards: May emit toxic fumes under fire conditions, including oxides of carbon.
Protective Equipment and Precautions: Firefighters should wear self-contained breathing apparatus, protective gloves, and safety goggles. Keep containers cool by spraying with water if exposed to fire.
Explosion Data: Not considered an explosion hazard in powdered or solid form but fine dust may form explosive mixtures with air in rare circumstances.
Personal Precautions: Ventilate area. Wear dust mask, chemical-resistant gloves, lab coat, and safety goggles to prevent contact. Avoid raising dust.
Environmental Precautions: Prevent entry into drains, surface water, and soil. Contain spill to smallest area possible.
Methods for Cleanup: Sweep or scoop up material using spark-proof tools, place in container for disposal. Use a HEPA vacuum or wet mop to avoid dust. Wash spill site with plenty of water after material pickup is complete.
Other Advice: Dispose of collected waste in accordance with local authority guidelines.
Safe Handling: Use only in well-ventilated areas, use appropriate personal protective equipment, avoid contact with skin, eyes, and clothing. Prevent formation of dust clouds.
Storage Recommendations: Keep container tightly closed in dry, cool, well-ventilated place, away from direct sunlight and sources of ignition. Store away from incompatible substances such as strong acids, bases, and oxidizing agents.
Packaging Materials: Use original containers or containers made of compatible chemical-resistant material.
Hygiene Requirements: Do not eat, drink, or smoke in work area. Always wash hands after handling.
Control Parameters: No occupational exposure limits set by OSHA, ACGIH, or NIOSH for Ipriflavone.
Engineering Controls: Employ local exhaust ventilation, fume hoods, or other engineering controls to keep airborne levels below recommended limits.
Personal Protection (Respiratory): Wear approved particulate respirator if dust forms.
Eyes: Use safety glasses with side shields or chemical splash goggles.
Hands: Wear suitable chemical-resistant gloves like nitrile or neoprene.
Skin/Body: Wear protective lab coat or apron.
General Protection: Keep good industrial hygiene and safety practices.
Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical smell
Melting Point: 150–154°C
Boiling Point: Decomposes before boiling
Vapor Pressure: Not significant at room temperature
Solubility: Insoluble in water, soluble in ethanol, DMSO, methanol
Density: About 1.3 g/cm³
pH: Not applicable (solid)
Partition Coefficient: log Kow: approximately 2.5
Other Information: Stable under normal conditions, sensitive to strong oxidizers.
Chemical Stability: Stable under recommended storage conditions.
Reactivity: No dangerous reactions known under normal conditions of use.
Conditions to Avoid: Extreme heat, moisture, exposure to light, strong oxidants or acids.
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products: May emit carbon monoxide, carbon dioxide, and other toxic fumes when heated or oxidized.
Polymerization: Will not occur.
Acute Toxicity: Oral LD50 (rat): >5000 mg/kg (low acute toxicity)
Skin Irritation: Mild irritation possible in sensitive individuals.
Eye Irritation: Mild irritation may occur. Wash with water.
Respiratory Sensitization: May cause temporary discomfort with dust exposure.
Chronic Effects: Possible minor liver enzyme changes, alteration in calcium metabolism with prolonged high exposure. No carcinogenic, mutagenic, or reproductive toxicity found in standard rodent studies.
Sensitization: Not expected to cause skin sensitization.
Other Data: Avoid excessive, repeated exposure until more long-term human safety information is available.
Ecotoxicity: No significant acute aquatic toxicity known at low concentrations, but avoid uncontrolled environmental release.
Mobility in Soil: Low solubility in water, will mainly remain in soil or sediment.
Persistence and Degradability: Slowly biodegradable; persistent in soil unless broken down by microbial action.
Bioaccumulative Potential: Moderate based on log Kow (~2.5).
Other Adverse Effects: No known large-scale environmental risk documented, yet best practice is to avoid unnecessary release.
Waste Treatment Methods: Collect material and residues in tightly closed containers. Dispose through licensed chemical waste disposal contractor.
Disposal of Contaminated Packaging: Contaminated packaging should be handled as chemical waste, rinsed and delivered to disposal plant in accordance with local, regional, or national regulations.
Special Precautions: Do not allow product to reach sewage system or water sources. Users bear the responsibility for safe disposal as per actual environmental regulations.
UN Number: Not regulated as hazardous material for transport by ADR, IMDG, or IATA.
Proper Shipping Name: Not classified as dangerous.
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not known to pose acute environmental risk during transport.
Special Precautions: Ship in closed containers away from food and animal feed, in compliance with regulations for non-hazardous substances.
TSCA Status: Listed or exempt
REACH/EC Status: May require registration
SARA Title III: Not regulated
California Prop 65: Not listed
WHMIS (Canada): Uncontrolled product according to WHMIS classification
Other Country Regulations: Follow national guidelines as required. Not subject to international restrictions as a hazardous substance but can have local workplace handling regulations in place.
Workplace Labeling: Ensure clear chemical identification and local safety instructions in workplaces using ipriflavone.
