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Product Name: (5-Thiazolyl)Methyl)-(4-Nitrophenyl) Carbonate
Chemical Formula: C12H8N2O4S
Synonyms: 4-Nitrophenyl [(5-thiazolyl)methyl] carbonate
CAS Number: 2045156-02-1
Use: Laboratory chemical, intermediate for organic synthesis, pharmaceutical research
Manufacturer: [Supplier Name and Address]
Emergency Contact: [Emergency Telephone Number and Address]
Classification: Acute Toxicity (Oral, Dermal, Inhalation), Eye Irritation Category 2A, Skin Sensitization
Label Elements: Harmful if inhaled, swallowed, or absorbed; causes serious eye irritation; may cause allergic skin reaction
Signal Word: Warning
Hazard Statements: H302: Harmful if swallowed; H315: Causes skin irritation; H319: Causes serious eye irritation; H334: May cause allergy or asthma symptoms or breathing difficulties
Precautionary Statements: Wear protective gloves/eye protection; avoid breathing dust/mist; wash thoroughly after handling.
Physical Hazards: Fine powder or crystals, yellow to light brown color, dust may cause respiratory irritation
Environmental Hazards: Toxic to aquatic organisms, may cause long-term effects in the aquatic environment
Chemical Entity: (5-Thiazolyl)Methyl)-(4-Nitrophenyl) Carbonate
Concentration: 98-100%
Impurities: Uncharacterized, trace synthetic byproducts, less than 2% total
Molecular Weight: 276.26 g/mol
Other Ingredients: None known
Hazardous Components: None aside from main compound
Decomposition Products: May release toxic gases under fire or high temperature conditions: nitrogen oxides, sulfur dioxide, carbon monoxide, carbon dioxide, nitrophenols
Inhalation: Remove to fresh air, seek medical attention if symptoms persist, provide oxygen or artificial respiration if needed
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, do not reuse clothing until washed, seek medical care if irritation develops
Eye Contact: Flush eyes with copious amounts of water for at least 15 minutes, lift eyelids occasionally, obtain medical attention immediately
Ingestion: Rinse mouth with water, do not induce vomiting, give water if victim is conscious, seek immediate medical assistance
Note to Physician: Treat symptomatically and supportively, consider treating for possible allergic reaction or sensitization
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water mist
Unsuitable Extinguishing Media: Direct stream of water as it may spread material
Special Hazards from Fire: May emit irritating, toxic fumes such as nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide when heated or combusted
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Move containers away from fire area if it can be done safely, cool unopened containers with water spray, avoid inhalation of product or combustion vapors
Personal Precautions: Evacuate personnel from area, ventilate area, use personal protective equipment including respirator, gloves, goggles
Environmental Precautions: Prevent spillage from entering drains, water courses, and soil
Clean-Up Methods: Scoop up and transfer to a suitable waste container, avoid causing dust, clean spill area thoroughly with water and detergent, dispose according to regulations
Special Instructions: Clear area of unnecessary personnel, avoid raising dust, ensure adequate ventilation throughout process
Emergency Procedures: Alert emergency personnel, isolate area, minimize contact with skin and eyes
Handling Precautions: Avoid inhalation, ingestion, and skin or eye contact, use only with appropriate engineering controls such as fume hood, wash hands after handling
Storage Conditions: Store in tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances and heat sources
Incompatibilities: Strong oxidizing agents, strong acids, strong bases, reducing agents
Other Advice: Keep away from ignition sources, store away from food and beverages, segregate from other chemicals that may trigger decomposition or hazardous reactions
Control Parameters: No occupational exposure limit established, handle as hazardous chemical
Engineering Controls: Use local exhaust ventilation, chemical fume hood, eye wash stations, safety showers
Personal Protective Equipment: Splash-proof safety goggles, chemical-resistant gloves (nitrile or equivalent), lab coat, suitable dust mask or respirator (N95 or better)
Hygiene Measures: Avoid contact with skin, eyes, and clothing, wash hands thoroughly before eating or drinking, do not smoke in work area
Environmental Controls: Avoid release to environment, monitor air for dust where used in bulk, use closed systems if possible
Appearance: Yellow to light brown crystalline powder
Odor: Weak or no characteristic odor
Odor Threshold: Not determined
pH: Not available (insoluble or partially soluble in water)
Melting Point: 130-135°C (estimate)
Boiling Point: Decomposes before boiling
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: May support combustion if exposed to open flame
Vapor Pressure: Negligible at ambient conditions
Vapor Density: Not applicable
Solubility: Poorly soluble in water, soluble in DMSO, DMF, acetonitrile, and some organic solvents
Partition Coefficient (log Kow): Not measured
Auto-ignition Temperature: Not determined
Decomposition Temperature: >160°C
Viscosity: Not applicable for solid
Chemical Stability: Stable under standard temperature and pressure, sensitive to moisture and high heat
Reactivity: Reacts with strong acids and bases, oxidizing and reducing agents
Possibility of Hazardous Reactions: Violent reaction possible with incompatible materials, may decompose under high temperature forming hazardous products
Conditions to Avoid: Moisture, prolonged exposure to air, heat, open flame
Incompatible Materials: Oxidizers, reducing agents, strong acids, strong bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur dioxide, carbon monoxide, carbon dioxide, nitrophenols, thiazoles
Acute Toxicity (Oral): Not fully characterized; predicted LD50 (rat, oral): 200-1000 mg/kg, harmful if swallowed
Acute Toxicity (Dermal): Potential to cause irritation and sensitization
Acute Toxicity (Inhalation): Dust may cause respiratory irritation, coughing, headache, possible allergic reactions
Skin Corrosion/Irritation: May cause redness, irritation, and dryness upon contact
Eye Damage/Irritation: Causes burning, tearing, redness, blurred vision, serious eye damage possible
Respiratory or Skin Sensitization: Potential for respiratory and dermal sensitization based on structure
Carcinogenicity: No data, not listed by IARC, NTP, or OSHA
Mutagenicity: Not tested in standard battery, structure suggests low but nonzero possibility
Reproductive Toxicity: No information; structurally, some concern for nitro-aromatics, caution advised
Repeated Dose Toxicity: Chronic exposure data not available, avoid repeated contact
Ecotoxicity: Expected to be highly toxic to aquatic organisms based on nitro-aromatic and thiazole content
Persistence and Degradability: Not rapidly biodegradable, likely to persist in soil and water
Bioaccumulation Potential: Likely to bioaccumulate in aquatic organisms, partition into fatty tissue
Mobility in Soil: Limited movement expected, tends to bind soil particles
Other Adverse Effects: May disrupt microbial activity in soil, potentially impact aquatic food chains
Avoid discharge into the environment and follow all laws regarding chemical disposal and release
Waste Treatment Methods: Handle as hazardous waste under local, state, and federal regulations
Disposal Containers: Use clearly labeled, tightly sealed hazardous waste containers
Disposal Methods: Incinerate in approved chemical incinerator, do not landfill unless permitted
Contaminated Packaging: Dispose of in the same way as hazardous chemical; do not reuse packaging
Other Disposal Recommendations: Contact licensed waste disposal contractor, comply with all regulations to prevent environmental contamination
UN Number: UN 2811 (Toxic solid, organic, n.o.s.)
UN Proper Shipping Name: Toxic solid, organic, n.o.s. ((5-Thiazolyl)Methyl)-(4-Nitrophenyl) Carbonate)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Prevent spillage during transport, keep container tightly closed, transport in secure, upright position, avoid rough handling
Transport Labels: Toxic substance, marine pollutant as per IMDG/IATA/DOT regulations
Reportable Quantity (RQ): Not established for this compound; handle as toxic chemical at all times
United States: Subject to TSCA regulations if imported or manufactured locally, not listed under SARA Title III, CERCLA, or RCRA for threshold reporting
Europe (REACH): Not on candidate lists; still requires registration for import or use over threshold quantities
Canada (DSL/NDSL): May require notification before import or manufacture
Japan, Australia, China: Consult local laws for any use, import, or distribution
Labeling Requirements: GHS-compliant labeling, toxic symbol, environmental hazard symbol
Other International Regulations: Local and national regulations may apply, registration and chemical control may vary, contact regulatory authorities for specific compliance needs
