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Product name: 5-Nitro-2-Aminophenol
Synonyms: 2-Amino-5-nitrophenol; 5-Nitro-o-aminophenol
Chemical formula: C6H6N2O3
CAS Number: 99-59-2
Recommended uses: Dye intermediate, laboratory reagent
Manufacturer/Supplier details: Contact chemical supplier, address and emergency phone number provided on shipment documents
Emergency information: National Chemical Safety hotline or local emergency number
GHS Classification: Acute Toxicity (Oral, Category 4), Eye Irritation (Category 2), Skin Sensitization (Category 1), Specific Target Organ Toxicity (Single Exposure, Category 3)
Pictograms: Exclamation mark, health hazard symbol
Signal word: Warning
Hazard statements: Harmful if swallowed, causes serious eye irritation, may cause an allergic skin reaction, may cause respiratory irritation
Precautionary statements: Avoid breathing dust, wear protective gloves/eye protection, wash thoroughly after handling, use only outdoors or in well-ventilated area, avoid release to the environment
Chemical name: 5-Nitro-2-Aminophenol
Common name and synonyms: 2-Amino-5-nitrophenol
Concentration or concentration ranges: 98-100% pure
Impurities and stabilizing additives: Only trace residuals expected, typically indicated on certificate of analysis
Inhalation: Move person to fresh air, seek medical attention if symptoms persist or worsen, provide oxygen if breathing is difficult
Skin contact: Remove contaminated clothing, rinse skin with soap and water for a minimum of fifteen minutes, seek medical help for skin reactions
Eye contact: Rinse immediately with water for at least fifteen minutes, keep eyelids open, remove contact lenses if present, seek medical assistance
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek prompt medical advice or treatment
Main symptoms and effects: Eye and skin irritation, nausea, headache, dizziness, allergic reactions on skin
Medical attention: Immediate for inhalation of dust or ingestion; monitor for allergic responses
Suitable extinguishing media: Dry chemical, water spray, carbon dioxide, foam
Specific hazards from combustion products: Toxic fumes of nitrogen oxides, carbon monoxide, unknown organic compounds can release during fire
Special protective equipment: Self-contained breathing apparatus, full protective clothing
Advice for firefighters: Move containers from fire area if safe, keep fire-exposed containers cool, avoid runoff entering waterways
Unusual hazards: Dust may pose explosion hazard in enclosed or poorly ventilated spaces
Personal precautions: Evacuate unprotected personnel, wear approved respirator, chemical goggles, gloves, and protective garment
Environmental precautions: Prevent entry into drains, watercourses, soil, alert authorities to large spills
Methods for containment and cleaning up: Stop leak if possible without risk, collect material using damp absorbent, place in labeled waste container, ventilate area well, wash spill site after pickup
Safe handling guidelines: Avoid dust formation, prevent skin and eye contact, use only in well-ventilated areas, do not eat, drink, or smoke where the powder or solution is used
Precautions for safe storage: Store in tightly closed container away from direct sunlight and moisture, keep at stable, cool temperature, segregate from incompatible substances such as oxidizers or strong acids
Incompatibilities: Avoid contact with strong bases, strong oxidants, acids, and reducing agents
Occupational exposure limits: No established threshold value for 5-Nitro-2-Aminophenol; keep levels low with good engineering controls
Engineering controls: Local exhaust, process enclosure, eyewash station and safety shower in area
Personal protective equipment: Respiratory protection (NIOSH-approved dust mask), chemical safety goggles, nitrile gloves, lab coat or chemical-resistant apron
Hygiene measures: Wash hands thoroughly after handling, keep away from food and beverages, remove contaminated clothing before entering eating areas
Appearance: Yellow to orange powder or crystals
Odor: Odorless or very faint odor
Odor threshold: Not established
pH: 5.5–7.5 (1% solution in water)
Melting point/range: 196–200°C
Boiling point/range: Decomposes before boiling
Flash point: Not available (likely non-flammable solid)
Evaporation rate: Not applicable
Flammability: Not highly flammable, but dust may combust
Vapor pressure: Negligible at ambient temperature
Vapor density: Not determined
Solubility: Slightly soluble in water, more soluble in ethanol or acetone
Partition coefficient (n-octanol/water): Not established
Autoignition temperature: Not established
Decomposition temperature: Above 200°C
Viscosity: Not applicable
Chemical stability: Stable under recommended storage and handling conditions
Possible hazardous reactions: Can react with strong oxidizing agents, acids, and bases
Conditions to avoid: Exposure to heat, flames, strong light, moisture
Incompatible materials: Oxidizers, acids, strong reducing agents
Decomposition products: Nitrogen oxides, carbon oxides, other organic fragments
Acute toxicity (oral): LD50 in rats reported as 373 mg/kg, risk of serious health effects at low doses
Acute toxicity (dermal): Not fully studied, avoid direct contact
Inhalation toxicity: Respiratory irritation, coughing, dizziness reported
Skin and eye irritation: Causes irritation, possible risk of allergic dermatitis
Sensitization: Documented in some individuals
Repeated dose toxicity: Not comprehensively studied, repeated exposure may lead to skin sensitization or organ system effects
Carcinogenicity/Mutagenicity: Not classified as carcinogen, has shown mutagenic effects in laboratory test systems
Other potential effects: Allergic skin reactions, dizziness, central nervous system symptoms
Ecotoxicity: Toxic to aquatic organisms based on related nitro and amino aromatic compounds, potential to disrupt aquatic ecosystems, avoid release to environment
Persistence and degradability: Tends to persist without rapid biodegradation
Bioaccumulation potential: Possible, based on chemical structure similarities
Mobility in soil: Moderately mobile, can migrate through soil to groundwater
Other adverse effects: Accumulation in sediment may impact benthic life, report large spills to environmental authorities
Disposal methods: Dispose of as hazardous chemical waste according to local and federal regulations, use certified disposal contractor if available
Contaminated packaging: Decontaminate prior to recycling if possible, or manage as hazardous material
Precautions: Do not release unneutralized residues into waterways, label waste containers clearly with contents and hazards
UN Number: Not regulated as a hazardous material for transport under most standards, cross-check local rules
UN proper shipping name: Not applicable for most ground shipping
Transport hazard class: Not classified
Packing group: Not assigned
Special precautions: Prevent package breakage, avoid leaks, ensure secure, upright containers during transit, attach safety documentation to shipments
OSHA: Regulated for workplace safety and exposure
TSCA: Listed on US Toxic Substances Control Act inventory
REACH: Pre-registered or registered depending on volume in European markets
Other listings: Included as hazardous substance in selected state, international, and transport regulations
Labeling: GHS and local authority-compliant symbols and warnings required on all storage and shipping containers
