© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 5-Nitro-1,3-Xylene
CAS Number: 13002-37-2
Synonyms: 5-Nitro-m-Xylene, 1,3-Dimethyl-5-nitrobenzene
Recommended Use: Intermediate for dyes, laboratory reagents, specialty chemical manufacturing
Manufacturer Contact: Chemical Safety Department, Emergency Telephone Number provided 24/7, Local and International support available, Immediate medical and environmental incident notification
Address: Listed full street address of manufacturer, emergency numbers for the region, email for technical and transport queries
Restrictions on Use: Not intended for drug, veterinary, or cosmetic applications, Not for household use, Only trained professionals should handle
GHS Classification: Acute Toxicity—Oral (Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2), Specific Target Organ Toxicity—Single Exposure (Category 3), Hazardous to Aquatic Environment (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, Causes skin irritation, Causes serious eye irritation, May cause respiratory irritation, Toxic to aquatic life with long lasting effects
Pictograms: Exclamation mark, Environmental hazard
Precautionary Statements: Avoid breathing dust or fumes, Wear protective gloves and eye/face protection, Wash hands thoroughly after use, Avoid release to environment, Do not eat, drink, or smoke when using product, If inhaled, move person to fresh air
Chemical Name: 5-Nitro-1,3-Xylene
CAS Number: 13002-37-2
Concentration: >98% by weight (purified form)
Impurities: Trace related isomers & residual starting material (<2%)
Additives: None, pure material without intentional additives or stabilizers
Molecular Formula: C8H9NO2
Molecular Weight: 151.17 g/mol
Inhalation: Remove from exposure, move to fresh air immediately, monitor breathing, supply oxygen if breathing becomes difficult, seek medical attention for respiratory symptoms
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with plenty of water and mild soap for 15 minutes, seek medical attention for persistent irritation
Eye Contact: Rinse eyes cautiously with water for at least 15–20 minutes, avoid rubbing eyes, remove contact lenses if present and easy to do, contact ophthalmologist
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical advice, provide symptomatic and supportive care
Important Symptoms: Irritation, redness, coughing, nausea, dizziness, headache, chemical burns possible on prolonged exposure
Immediate Medical Attention: Required for inhalation of dusts/fumes, ingestion of substance, or contact with sensitive mucous membranes
Suitable Extinguishing Media: Use dry chemical powder, foam, carbon dioxide (CO2), water spray for cooling, but avoid direct water jet
Specific Hazards: Emits toxic fumes of nitrogen oxides, carbon oxides under fire conditions, dust may form explosive mixtures with air, possible pressure build-up in sealed containers
Special Protective Equipment: Full protective suit, self-contained breathing apparatus, chemical resistant gloves and boots required for firefighting personnel
Firefighting Instructions: Approach from upwind, avoid inhalation of fumes, use water spray to cool exposed non-burning containers, evacuate area for significant fire
Further Information: Prevent fire-fighting water from entering drains or watercourses, contain runoff with sand or earth
Personal Precautions: Eliminate ignition sources, ventilate area, isolate spill from people and animals, avoid breathing dust, put on appropriate personal protective equipment
Environmental Precautions: Prevent entry to sewers or waterways, notify authorities if waterways are contaminated, contain and collect spillage for safe disposal
Methods for Cleanup: Sweep up carefully and transfer to suitable closed containers, use non-sparking tools, minimize dust generation, clean contaminated surface with water and compatible detergent
Reference to Other Sections: Consult exposure controls, disposal information, and regulatory guidance for safe handing and cleanup
Safe Handling: Avoid contact with skin, eyes, and clothing, minimize airborne dust, use only in well-ventilated areas or chemical fume hood, never handle near open flame or heat sources, wash hands and face after use
Incompatible Materials: Strong oxidizers, acids, bases, reducing agents, avoid storage with combustibles
Storage Requirements: Store tightly closed in cool, dry, well-ventilated, designated chemical area, keep away from direct sunlight and incompatible substances, store in original containers or compatible replacements
Special Storage Considerations: Store away from moisture, inspect container integrity regularly, avoid accidental mixing with other chemicals
Packaging Materials: Use containers made from compatible plastics or glass, tightly sealed for shipping and storage stability
Engineering Controls: Use chemical fume hood or local exhaust ventilation for dust/fume control, negative pressure facility preferred, maintain eye wash station and safety shower within immediate area
Exposure Limits: No established OSHA, ACGIH, NIOSH, or EU workplace exposure limits as of latest available data, recommend internal company TWA of 1 mg/m3 (consult updated national regulations)
Personal Protective Equipment: Safety goggles, impervious gloves (nitrile, neoprene), long-sleeved chemical-resistant clothing, disposable respirators or P100/FFP3 for dust
Hygiene Measures: Change contaminated clothing, prohibit food or drink in chemical areas, wash hands thoroughly after handling
Environmental Exposure Controls: Use spill trays, filters, and closed systems where possible to minimize environmental releases
Appearance: Yellow crystalline solid or powder
Odor: Faint aromatic odor
Melting Point/Freezing Point: 75–78°C
Boiling Point/Range: 285–287°C
Solubility: Insoluble in water, soluble in organic solvents such as ethanol, acetone, diethyl ether, and benzene
pH: Not applicable (solid, non-aqueous)
Vapor Pressure: Negligible at room temperature
Density: 1.19 g/cm3 at 20°C
Partition Coefficient (log Pow): Estimated 2.5–3.2 (moderate potential for bioaccumulation)
Evaporation Rate: Not significant under ambient conditions
Flash Point: 150°C (closed cup)
Auto-Ignition Temperature: Data not available
Explosive Properties: Not classified as explosive, but may form hazardous dust-air mixtures
Oxidizing Properties: Not classified as oxidizer
Other Information: Stable under recommended storage conditions, strong yellow color facilitates visual identification in lab settings
Chemical Stability: Stable in closed containers at room temperature, avoid moisture and incompatible materials
Conditions to Avoid: High temperatures, flame, spark, static electricity, strong sunlight, strong agitation generating dust clouds
Incompatible Materials: Oxidizing agents, reducing agents, strong acids, strong bases, peroxides
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, possible toxic volatile organic compounds
Polymerization: No hazardous polymerization expected
Reactivity: Not violently reactive, use standard chemical safety procedures, secondary reactions possible with strong oxidizers
Acute Toxicity: Harmful if swallowed (estimated LD50 in rats 350–600 mg/kg), skin contact and dust inhalation may produce moderate irritation
Skin Corrosion/Irritation: Mild to moderate irritation based on similar chemicals, possible redness, drying, or cracking of skin
Serious Eye Damage/Irritation: Severe eye irritation, may cause conjunctivitis, burning, tears, temporary visual discomfort
Respiratory Sensitization: Not classified, but inhalation of dust may irritate upper airways and lungs
Chronic Effects: No data linking 5-Nitro-1,3-xylene to cancer or reproductive toxicity, long-term exposure should be avoided due to lack of conclusive research
Other Effects: May cause headache, dizziness, nausea, fatigue, allergic reaction in sensitized individuals
Target Organs: Eyes, skin, respiratory tract
Toxicokinetics: Limited data, structurally related nitro-aromatic compounds can be absorbed and slowly metabolized in the body
Ecotoxicity: Moderately toxic to aquatic organisms, estimated EC50 (Daphnia magna) 1–10 mg/L, potential for bioaccumulation exists
Persistence and Degradability: Not readily biodegradable, persists in aquatic environments, predicted to have half-life of weeks to months
Bioaccumulative Potential: Log Kow between 2.5 and 3.2 suggests moderate potential, may accumulate in sediment and biota
Mobility in Soil: Moderately mobile, can adhere to organic material in soil
Other Adverse Effects: Avoid spillage and accidental release, contamination harms aquatic life and may enter food chains
Waste Treatment Methods: Dispose of as hazardous chemical waste through licensed disposal contractor, incineration or landfilling according to regulations
Contaminated Packaging: Triple rinse non-returnable containers, offer for hazardous waste collection
Disposal Precautions: Never dispose in municipal drains or common landfill, prevent environmental contamination, dilute solutions still classified as hazardous
Regulatory Considerations: Rely on state, federal, and local hazardous waste rules, UN and IMDG guidance where applicable
UN Number: UN 2811
Proper Shipping Name: Toxic Solid, Organic, N.O.S. (5-Nitro-1,3-xylene)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labels Required: Toxic (Skull and crossbones)
Marine Pollutant: Yes, classified for aquatic hazard
Special Precautions: Keep separate from foodstuffs, segregate from strong oxidizers, emergency action codes required for spillage/leakage during transport
Regulatory Transport Reference: Compliant with ADR/RID, IMDG, IATA codes for safe land, sea, and air shipment
OSHA Status: Not specifically listed under 29 CFR 1910.1000, generally controlled as a hazardous chemical
TSCA: Listed on U.S. Toxic Substances Control Act Inventory
REACH Status: Pre-registered, subject to downstream user notification requirements within the EU
SARA Title III: Subject to Section 311/312 hazard classification (Acute Health Hazard), not on TPQ or EHS lists
California Proposition 65: Not listed as a known carcinogen or reproductive toxin as of most current inventory, best practice restricts non-industrial uses
Other National Inventories: Australia (AICS), Canada (DSL), Japan (ENCS), Korea (KECI) include listing for 5-Nitro-1,3-xylene
WHMIS Classification (Canada): D2B (Toxic Material Causing Other Toxic Effects)
Voluntary Guidelines: Follow Key Global Harmonized System (GHS) labelling and handling protocols
