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Material Safety Data Sheet: 5-Methoxytryptamine Hydrochloride

Identification

Product Name: 5-Methoxytryptamine Hydrochloride
Chemical Name: 2-(5-Methoxy-1H-indol-3-yl)ethanamine hydrochloride
Synonyms: 5-MT HCl, Mexamine Hydrochloride
CAS Number: 13394-18-2
EC Number: 236-561-6
Recommended Use: Laboratory chemical, research and development
Manufacturer Address: Details available upon request
Emergency Contact: Local Poison Control Center or medical professional

Hazard Identification

GHS Classification: Not classified as hazardous according to Regulation (EC) No. 1272/2008
Hazard Statements: No known acute or chronic toxicity in small quantities, but material can irritate respiratory tract, eyes, and skin upon direct contact
Signal Word: None required
Pictograms: None assigned
Precautionary Statements: Avoid direct inhalation, ingestion, or skin contact; wash thoroughly after handling
Physical Hazards: May release dust when handled

Composition / Information on Ingredients

Chemical Identity: 5-Methoxytryptamine Hydrochloride
Percent by Weight: ≥98% pure
Impurities or Additives: Trace inorganic salts, moisture possibly below 1%
Molecular Formula: C11H14ClN2O
Molecular Weight: 226.7 g/mol
Ingredient Type: Single substance

First Aid Measures

Inhalation: Remove person to fresh air; seek medical attention if symptoms persist
Skin Contact: Wash with plenty of soap and water for at least 15 minutes; remove contaminated clothing
Eye Contact: Rinse eyes thoroughly with water for several minutes, lifting eyelids occasionally
Ingestion: Rinse mouth with water, do not induce vomiting; obtain medical attention
Advice for Physicians: Treat symptoms supportively; no specific antidote known

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Strong water jets could disperse dust
Hazards from Combustion Products: May produce nitrogen oxides, hydrogen chloride, carbon monoxide and carbon dioxide
Firefighter Protective Equipment: Self-contained breathing apparatus and full protective gear recommended
Special Procedures: Keep containers cool, avoid breathing smoke

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment, avoid breathing dust
Environmental Precautions: Prevent entry into drains, soil, or waterways
Containment Methods: Sweep or shovel up material and collect in a suitable, labeled waste container
Clean-Up Methods: Wash area thoroughly with water after removal
Disposal Procedures: Handle in accordance with local regulations

Handling and Storage

Precautions for Safe Handling: Avoid dust formation, handle in well-ventilated areas; keep away from food and beverages
Personal Hygiene: Wash thoroughly after handling
Storage Conditions: Store in tightly closed containers, in a dry, cool, well-ventilated place
Temperature Range: Store at ambient or below, protected from light and moisture
Incompatible Materials: Strong oxidizers, strong acids or bases
Packaging Materials: Use chemically resistant, sealed containers

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits
Engineering Controls: Use local exhaust or general laboratory ventilation to minimize airborne concentrations
Eye Protection: Safety goggles with side shields
Skin Protection: Nitrile or latex gloves and a lab coat
Respiratory Protection: Particulate respirator if dust generation possible
Hygiene Measures: Do not eat, drink, or smoke while handling the substance

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH: 3.5-4.5 (1% aqueous solution)
Melting Point: 180-185°C (decomposition)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Not classified as flammable-solid
Vapor Pressure: Not applicable (solid)
Relative Density: 1.14-1.19 (water=1)
Solubility: Soluble in water, ethanol, methanol; insoluble in ether
Partition Coefficient (log Kow): Not determined
Auto-ignition Temperature: No data
Decomposition Temperature: >180°C
Viscosity: Not applicable (solid)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions expected under normal conditions
Conditions to Avoid: High temperatures, exposure to strong light, moisture
Incompatible Substances: Strong oxidizers, acids, bases
Hazardous Decomposition Products: Oxides of carbon and nitrogen, hydrogen chloride gas

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Data not fully available; low toxicity expected based on structure and related compounds
LD50 (Oral/Rat): Not established
Skin Irritation: May cause mild irritation
Eye Irritation: May cause mild irritation or redness
Respiratory Effects: Dust may irritate mucous membranes
Sensitization: Not classified as a sensitizer
Chronic Effects: No data for carcinogenicity, mutagenicity, or reproductive toxicity; low risk expected for accidental laboratory exposure; always limit exposure

Ecological Information

Ecotoxicity: No specific data; use caution to prevent environmental release
Aquatic Toxicity: No information on LC50 or EC50; likely low persistence, do not discard in drains
Persistence and Degradability: Product expected to be readily biodegradable
Bioaccumulation Potential: Likely low due to water solubility
Mobility in Soil: Product soluble in water, may leach through soil
Additonal Notes: Avoid contamination of waterways and soil

Disposal Considerations

Waste Disposal Methods: Dispose as chemical waste in accordance with local, regional, or national regulations
Contaminated Packaging: Rinse and dispose of with chemical waste
Sewage Disposal Restrictions: Do not release into the environment or sewage system
Recommended Disposal: Use licensed chemical disposal contractor if available

Transport Information

UN Number: Not regulated as dangerous goods
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: Not considered marine pollutant
Special Precautions: Keep package tightly sealed, prevent spillage, avoid direct contact
Transport Labels: None required

Regulatory Information

Regulatory Status: Not listed as hazardous under major chemical regulations such as the US OSHA Hazard Communication Standard, EU CLP, or Canadian WHMIS
Inventory Listings: Listed or exempted on chemical inventories in the US (TSCA), EU (EINECS/ELINCS), and Japan (ENCS)
Restricted Uses: For research and laboratory use only; not for food, drug, or household use
Safety Phrases: Use standard laboratory precautions and wear appropriate protective equipment
International Regulations: Subject to local and international chemical safety and environmental regulations