© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 4-Nitrosophenol
Chemical Formula: C6H5NO2
CAS Number: 104-91-6
Synonyms: p-Nitrosophenol, para-Nitrosophenol
Recommended Use: Laboratory solvent, research reagent
Manufacturer/Supplier: [Insert supplier or lab contact]
Emergency Contact: Refer to local regulations for emergency number
GHS Classification: Acute Toxicity (Oral): Category 3; Acute Toxicity (Inhalation): Category 3; Skin Irritation: Category 2; Eye Irritation: Category 2A
Pictograms: Skull and crossbones, exclamation mark
Signal Word: Danger
Hazard Statements: Toxic if swallowed. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation
Precautionary Statements: Avoid breathing dust. Wash skin after handling. Use only outdoors or in well-ventilated area. Wear protective gloves, eye protection, and face protection. If exposed or concerned, get medical advice
Chemical Name: 4-Nitrosophenol
Concentration: 98–100%
CAS Number: 104-91-6
Impurities and Stabilizers: Not known to contain significant impurities that affect classification or health
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses if present. Seek immediate medical attention
Skin Contact: Remove contaminated clothing. Wash skin immediately with soap and plenty of water. Get medical advice if symptoms develop
Inhalation: Remove person to fresh air and keep at rest. If breathing is difficult, administer oxygen. Seek medical help
Ingestion: Rinse mouth. Do NOT induce vomiting. Call a poison control center or doctor right away
Most Important Symptoms: Coughing, sore throat, respiratory tract irritation, nausea, headache, skin and eye irritation
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: Avoid water jet
Specific Hazards: Thermal decomposition releases toxic oxides of nitrogen, carbon monoxide, and carbon dioxide
Protective Equipment/Precautions: Wear self-contained breathing apparatus and full protective gear.
Firefighting Procedures: Cool containers exposed to flames. Evacuate area if necessary. Prevent firefighting runoff from entering drains or waterway
Personal Precautions: Evacuate non-essential personnel. Wear chemical resistant gloves, protective goggles, and suitable clothing. Provide adequate ventilation
Environmental Precautions: Avoid discharge into drains, surface water, and soil
Methods for Containment and Cleaning: Isolate and contain spill with inert materials like sand or earth. Scoop up and place into labeled waste containers. Wash affected area with water and detergent. Dispose as hazardous waste. Prevent dust formation
Precautions for Safe Handling: Maintain proper lab cleanliness. Avoid inhalation or contact with skin and eyes. Use in fume hood or ventilated area. Do not handle until all safety precautions have been read and understood
Conditions for Safe Storage: Store tightly closed in cool, dry, ventilated area away from heat, light, and incompatible substances. Original containers help prevent contamination. Keep away from oxidizing agents and strong acids or bases. Use secondary containment for bulk storage
Exposure Limits: No specific OSHA or ACGIH values assigned for this compound. Minimize exposure as much as possible
Engineering Controls: Fume hood, local exhaust, or proper room ventilation required
Personal Protective Equipment: Wear chemical splash goggles, nitrile gloves, and lab coat. If dust or vapors may be present, use NIOSH-approved respirator
Hygiene Measures: Wash hands and face thoroughly after handling, before eating, drinking, or smoking. Remove and wash contaminated clothing before reuse
Appearance: Green-yellow to yellow-brown crystalline powder
Odor: Faint characteristic odor
Melting Point: 116–118°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in ethanol, slightly soluble in water
Flash Point: Not available
Vapor Pressure: Negligible at room temperature
Relative Density: 1.31 (water = 1.00)
pH: Not available (aqueous solution)
Partition Coefficient (n-octanol/water): Not available
Chemical Stability: Stable under normal conditions of use and storage
Hazardous Reactions: Reacts with strong oxidizers, acids, and reducing agents
Decomposition Products: Toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide
Conditions to Avoid: Excessive heat, open flames, direct sunlight, moisture
Polymerization: Not known to occur
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Effects: Toxic if swallowed or inhaled. Causes serious irritation to skin, eyes, and respiratory tract
Chronic Effects: Prolonged or repeated exposure may damage blood, kidneys, or liver
Carcinogenicity: Not listed by IARC, NTP, OSHA
LD50 (Oral, rat): 200 mg/kg (approximate)
Symptoms of Overexposure: Headache, dizziness, nausea, cyanosis, methemoglobinemia, confusion, convulsions
Ecotoxicity: Harmful to aquatic organisms, may cause long-term adverse effects in aquatic environment
Persistence and Degradability: Limited biodegradation, persistency possible in soil and water
Bioaccumulation Potential: Low to moderate, limited data available
Mobility in Soil: Can migrate in moist conditions; hazardous to groundwater
Other Adverse Effects: Avoid release to environment. Regulatory restrictions may apply to water discharge
Product Disposal: Deliver unwanted chemicals to licensed hazardous waste disposal company. Solid residue and contaminated packaging require chemical waste management
Contaminated Packaging: Rinse then dispose of as hazardous waste as per local, state, or national laws
Special Precautions: Prevent chemical from contaminating water sources or soil during disposal
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (Contains 4-Nitrosophenol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Special Transport Precautions: Keep container tightly closed during transit. Protect from physical damage, moisture, and ignition. Notify transporter of toxic hazard
OSHA HazCom: This material is hazardous according to OSHA Hazard Communication Standard
TSCA Inventory: Substance listed
SARA Title III (Sections 302/304/313): No specific reporting requirements identified
REACH Status (EU): Subject to registration requirements
WHMIS (Canada): D1A (Very toxic material), D2B (Toxic material causing other effects)
Other Regulation: State or country-specific regulations may apply
