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Material Safety Data Sheet: 4-Nitroso-N,N-Diethylaniline

Identification

Product Name: 4-Nitroso-N,N-Diethylaniline
Chemical Formula: C10H14N2O
CAS Number: 156-25-2
Synonyms: N,N-Diethyl-p-nitrosoaniline
Recommended Use: Laboratory reagents, dye intermediates, chemical synthesis
Manufacturer: Contact information available on container label or provided through supplier
Emergency Telephone: Use local emergency number or institutional safety contacts

Hazard Identification

GHS Classification: Acute toxicity (Oral, Dermal, Inhalation), Eye irritation, Skin sensitization
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye damage, suspected of causing genetic defects
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, do not eat or drink during use, wear suitable gloves and eye protection
Physical Hazards: Not classified as flammable but may support combustion under certain conditions
Health Hazards: Absorption through skin possible, serious risk of eye injury, inhalation may damage respiratory system
Environmental Hazards: Harmful to aquatic life with long-lasting effects

Composition / Information on Ingredients

Chemical Name: 4-Nitroso-N,N-Diethylaniline
Concentration: 98% or above
Impurities: Trace organic contaminants and by-products below 2%
Other Components: No stabilizers or solvents, pure compound form
Molecular Weight: 178.23 g/mol

First Aid Measures

Inhalation: Move victim to fresh air, keep in rest position, provide oxygen if breathing is difficult, seek medical advice
Skin Contact: Remove contaminated clothing, wash affected area with soap and plenty of water for at least 15 minutes, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get immediate medical help
Ingestion: Rinse mouth thoroughly, do not induce vomiting unless instructed by medical personnel, give water if conscious, seek medical attention
Important Symptoms: Nausea, headache, dizziness, skin redness, eye pain and blurred vision
Medical Attention: Immediate treatment recommended for eye and ingestion exposures

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or foam
Unsuitable Extinguishing Media: Direct stream of water may spread material
Special Hazards: Combustion may release toxic nitrogen oxides, carbon monoxide, irritating acidic fumes
Firefighting Precautions: Protective clothing and self-contained breathing apparatus required for fire personnel
Thermal Decomposition: Produces hazardous gases including oxides of nitrogen and carbon
Explosion Risk: No evidence of explosive properties in product data but avoid accumulation of dust

Accidental Release Measures

Personal Protection: Wear gloves, protective goggles, and particulate respirator if dust forms
Spill Cleanup Methods: Ventilate area, avoid raising dust, use inert absorbent such as vermiculite, sweep up and place in suitable chemical waste container
Environmental Precautions: Prevent product from entering drains, waterways, or soil
Decontamination: Wash spill site with plenty of water and detergent after material has been collected
Disposal: Collect debris using spark-proof tools and dispose of according to local regulations

Handling and Storage

Handling: Use in a well-ventilated area or fume hood, avoid inhaling dust and contact with skin or eyes, do not eat, drink or smoke during handling
Storage Conditions: Keep in tightly closed container, protect from moisture, store in cool dry area away from incompatible chemicals such as strong acids, oxidizers and reducing agents
Incompatible Materials: Avoid contact with oxidizers, acids, strong bases, and reducing agents
Safe Storage Design: Use secondary containment when storing large quantities, label container clearly, restrict access to designated personnel

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA, ACGIH or EU values for this compound as of last update
Engineering Controls: Use chemical fume hood, local exhaust ventilation, safety showers and eyewash stations
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles, laboratory coat, dust respirator if dust is generated
Hygiene Measures: Wash hands and face after handling, change contaminated clothing immediately
Environmental Control: Avoid uncontrolled discharge, use closed systems for processes if possible

Physical and Chemical Properties

Appearance: Yellow to green powder or crystals
Odor: Characteristic, faintly aromatic
pH: Not applicable (insoluble in water)
Boiling Point: Data not available
Melting Point: 97–99 °C
Vapor Pressure: Negligible at room temperature
Water Solubility: Insoluble, soluble in ethanol, ether, chloroform
Density: Approximately 1.12 g/cm³
Partition Coefficient (log Pow): Data not reported
Flash Point: Not established
Auto-ignition Temperature: Data not available
Explosive limits: No evidence of explosive properties under normal conditions

Stability and Reactivity

Chemical Stability: Stable under ordinary conditions with proper storage
Reactivity: May react with oxidizers or acids producing hazardous gases
Hazardous Reactions: Contact with strong reducing agents or oxidizing agents may cause violent reactions
Conditions to Avoid: Exposure to moisture, excessive heat, direct sunlight, sources of ignition
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, other toxic vapors

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled or absorbed
Oral LD50 (Rat): Estimated between 100 and 300 mg/kg
Skin Corrosion/Irritation: Causes irritation, prolonged contact may worsen effects
Eye Damage/Irritation: Risk of serious damage
Respiratory Effects: Inhalation leads to coughing, shortness of breath, dizziness
Sensitization: May cause skin sensitization in predisposed individuals
Chronic Toxicity: Possible risk of long-term adverse effects, evidence limited
Cancer, Mutagenicity, Reproductive Effects: Not enough data for specific classification but nitrosoamines in general have shown mutagenic potential in some studies
Routes of Exposure: Inhalation, ingestion, dermal contact

Ecological Information

Aquatic Toxicity: Harmful to aquatic life, risk of long-term effects, experimental values suggest moderate toxicity
Persistence and Degradability: Likely not readily biodegradable, may persist in soil and water
Bioaccumulative Potential: No measured data, but moderate log Pow suggests possible accumulation
Mobility in Soil: Likely low due to low solubility
Other Effects: Avoid unintended release, pollutants may impact wastewater processing systems

Disposal Considerations

Waste Treatment Methods: Incinerate or use licensed chemical waste facility
Contaminated Packaging: Dispose of as hazardous waste, triple-rinse containers if practiced in your jurisdiction
Handling of Waste: Wear PPE at all times, keep away from incompatible materials, restrict to authorized personnel
Regulatory Requirements: Comply with national, regional, and local regulations for hazardous chemical waste
Do Not: Pour down the drain, discard in regular garbage, or leave unattended

Transport Information

UN Number: Not specifically assigned as of database review
Proper Shipping Name: Chemical substance, solid, not otherwise specified
Transport Hazard Class: Varies by region; treat as toxic solid
Packing Group: III (if assigned)
Label Requirements: Toxic, irritant symbol required
Marine Pollutant: Not specifically listed, but best practice to avoid environmental release
Special Precautions: Keep in original packaging, avoid breakage, store away from food and feed during transportation

Regulatory Information

Labelling: Requires hazard pictograms for toxic and irritant materials
US Regulatory Status: Not listed under CERCLA, RCRA or SARA Title III as of current data; handle as hazardous substance in lab setting
European Union: Classified under CLP Regulation, subject to workplace safety and environmental protection standards
Inventory Listings: Presence in EINECS, TSCA inventory to be checked for new updates
Employer Responsibility: Maintain access to MSDS, train workers in chemical hygiene plan, provide necessary PPE and emergency protocols
Specific Local Regulations: Abide by all applicable state and regional safety guidelines for workplace chemical safety