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Product Name: 4-Nitroiodobenzene
Chemical Formula: C6H4INO2
Synonyms: p-Iodonitrobenzene, para-Nitroiodobenzene
CAS Number: 636-98-6
Recommended Use: Laboratory chemicals, organic synthesis, research.
Manufacturer/Supplier Information: Information to be provided on actual supplier contact, including emergency telephone numbers, address, and email for inquiry.
Emergency Number: Local emergency medical or poison control center.
Classification: Acute toxicity, Skin and eye irritation, Respiratory irritation, Environmental hazard.
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may damage respiratory passages on inhalation, harmful to aquatic life.
GHS Label Elements: Exclamation mark, Health hazard, Environmental hazard
Precautionary Statements: Avoid breathing dust or vapors, wash thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves, clothing, and eye protection.
Routes of Entry: Inhalation, ingestion, skin and eye contact
Target Organs: Eyes, skin, respiratory system
Chemical Name: 4-Nitroiodobenzene
CAS Number: 636-98-6
Concentration: 97-100%
Impurities: Trace amounts of other iodo-nitrobenzenes or solvents from synthesis
Molecular Weight: 249.01 g/mol
Inhalation: Remove to fresh air, seek medical attention if symptoms persist, allow the person to rest.
Skin Contact: Wash exposed skin with soap and plenty of running water for at least 15 minutes, remove contaminated clothing, seek medical help for irritation, itching, or redness.
Eye Contact: Rinse opened eye immediately with water for at least 15 minutes keeping eyelids open, seek urgent ophthalmological advice.
Ingestion: Rinse mouth with water but do not induce vomiting, seek medical assistance immediately, monitor for symptoms such as nausea, vomiting, or abdominal discomfort.
Most Important Symptoms: Dermatitis, respiratory distress, stomach discomfort, redness or swelling at contact sites, coughing, irritation.
Notes for Doctor: Treat symptomatically, administer supportive measures as required.
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: Direct water jet in case of spillage or heavy contamination
Special Hazards: Decomposes on heating to produce toxic fumes of nitrogen oxides, iodine vapors, carbon monoxide, carbon dioxide
Fire-fighting Instructions: Wear self-contained breathing apparatus and full protective gear, keep uninvolved personnel away
Explosion Info: Dust may create explosive mixture in air although it rarely forms enough dust due to crystalline form
Personal Precautions: Avoid dust formation, wear protective respiratory equipment, chemical goggles, gloves, lab coat
Environmental Precautions: Prevent spillage from entering surface waterways, sewer systems, and soil
Clean-up Procedures: Scoop up or sweep solid carefully minimizing dust, place in well-labeled waste container for disposal, ventilate area and wash spill site after cleanup
Decontamination: Wash contaminated surfaces with water and suitable detergent to remove traces
Handling: Use in fume hood or well-ventilated setting, avoid generating dust, avoid breathing in particles, do not eat or drink while handling, keep container tightly sealed
Storage Conditions: Store away from direct sunlight and incompatible substances, keep at ambient temperature in original labeled container, avoid moisture and oxidizing agents
Storage Class: Chemical storage for hazardous organics
Precautions: Maintain strict hygiene measures, wash hands thoroughly after handling, keep all laboratory containers tightly closed when not in use
Occupational Exposure Limits: No specific limits established; recommend minimizing exposure as much as possible
Engineering Controls: Use chemical fume hood, eye wash station, and safety shower
Personal Protection: Wear chemical-resistant gloves (nitrile, neoprene), safety goggles, lab coat, and approved respirator in case of dust or vapor formation
Hygiene: Avoid inhaling dust or vapors, do not allow product contact with skin, eyes, or clothing, wash hands before breaks and after use
Environmental Controls: Prevent chemical from entering drainage or watercourses, use containment and absorbents as necessary
Appearance: Pale yellow, crystalline solid
Odor: Characteristic, mild aromatic odor
Odor Threshold: Not determined
pH: Neutral to mildly acidic in aqueous solution
Melting Point: 156–158°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable (solid)
Evaporation Rate: Not applicable
Flammability: May burn under intense heating but does not ignite easily
Vapor Pressure: Very low at room temperature
Vapor Density: Not relevant
Solubility: Insoluble in water, soluble in organic solvents such as ethanol, acetone, and benzene
Partition Coefficient (n-octanol/water): Data not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: Decomposes above 200°C with toxic gas formation
Viscosity: Not applicable (solid)
Density: 2.17 g/cm³
Stability: Stable under recommended storage conditions
Reactivity: Not reactive with most chemicals under normal conditions
Incompatible Materials: Strong oxidizing agents, strong bases, reducing agents
Hazardous Decomposition Products: Releases toxic gases including iodine, nitrogen oxides, carbon monoxide, carbon dioxide on decomposition or combustion
Conditions to Avoid: Heat, flames, sources of ignition, excessive humidity, incompatible materials
Polymerization: Will not occur
Possible Routes of Exposure: Eye contact, skin contact, ingestion, inhalation
Acute Effects: Skin or eye irritation, respiratory and digestive tract irritation, symptoms such as redness, coughing, sore throat, abdominal discomfort
Chronic Effects: Prolonged or repeated exposure may cause dermatitis or worsen asthma in susceptible individuals
Toxicity Data: Exact LD50 values for animals not broadly published, but acute toxicity evidence suggests harmful upon intake or significant exposure
Carcinogenicity: Not listed as carcinogenic by ACGIH, IARC, NTP, or OSHA
Mutagenicity: No mutation data available; best handled with care due to nitro and iodine content
Reproductive Toxicity: No reproductive toxicity studies found
Sensitization: Possible skin sensitizer from repeated exposure
Symptoms of Exposure: Dermal irritation, cough, headache, dizziness, sore eyes, stomach pain if swallowed
Medical Conditions Aggravated: Pre-existing skin, eye, or respiratory disorders
Toxicity to Aquatic Life: Harmful to aquatic organisms based on iodine and nitroaromatic toxicity, may cause localized adverse effects if released to environment
Persistence/Degradability: Expected to be persistent; nitroaromatics and halogenated benzenes degrade slowly
Bioaccumulative Potential: May bioaccumulate in aquatic or soil organisms
Mobility in Soil: Limited mobility in soil due to low water solubility
Environmental Fate: Once released, may persist in water, sediment, and soil environments, avoid any environmental release
Other Ecological Notes: Byproducts from breakdown (like free iodine) may impact surrounding organisms or ecological processes
Waste Disposal Method: Dispose of as hazardous organic chemical waste in accordance with local, state, and federal regulations
Recommended Disposal Containers: Use sealed, labeled containers resistant to chemical attack
Precautions for Disposal: Do not dispose via drains, keep out of landfill and water systems, deliver to licensed chemical waste disposer
Waste Codes: Use appropriate codes for halogenated organic laboratory waste, check local requirements for nitroaromatic compounds
Contaminated Packaging: Triple rinse or treat as hazardous material; follow local legislation for chemical residue disposal
UN Number: Consult regulations for specifics based on shipping method and concentration;
Proper Shipping Name: 4-Nitroiodobenzene
Transport Hazard Class: Class 6.1 (toxic substances), may also be classified as environmentally hazardous
Packing Group: III
Environmental Hazards During Transport: Mark as hazardous to aquatic environments if required
Transport Labels: Toxic, environmentally hazardous
Special Precautions: Avoid container damage, package securely to prevent leaks, follow local and international shipping requirements, report and contain accidental spillage immediately
ADR/RID/IMDG Code: Review current transport codes for compliance
Inventory Status: Listed or covered under certain national chemical inventories (TSCA, REACH, etc.)
Occupational Regulatory Limits: No established OSHA PEL, ACGIH TLV, NIOSH REL
Right-to-Know Regulations: Subject to hazard communication and labeling standards in most areas
SARA Title III : Not specifically listed, but reporting required if threshold quantities are exceeded
Other Regulations: Subject to environmental, occupational, transportation, and chemical safety regulations varying by country, users must confirm current restrictions and obligations before use
Labeling Requirements: Clearly mark with hazard, risk, and safety advice, include pictograms, and communicate emergency procedures to all handlers
Restrictions: Not for use in pharmaceutical, cosmetic, food, or feed applications
