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Product Name: 4-Nitrobromobenzene
Chemical Formula: C6H4BrNO2
CAS Number: 586-78-7
Recommended Use: Research, chemical synthesis, chemical manufacturing
Manufacturer: Various global chemical supply companies
Emergency Contact: Refer to supplier’s emergency line or local poison control center
Classification: Acute toxicity (oral, dermal, inhalation), skin and eye irritant, possible mutagenicity
GHS Label: Skull and crossbones, exclamation mark
Hazard Statements: Can cause skin irritation, respiratory irritation, serious eye damage, and harm if swallowed or inhaled
Precautionary Statements: Avoid breathing dust or vapors, wash skin after handling, keep container tightly closed
Pictograms: Use GHS07 (exclamation mark), GHS06 (skull and crossbones) on containers
Other Hazards: Harmful to aquatic life with long-lasting effects
Chemical Name: 4-Nitrobromobenzene
Synonyms: p-Bromonitrobenzene
CAS Number: 586-78-7
Concentration: 98–100% (pure substance)
Impurities: Typically traces of related halogenated aromatics or nitro compounds
Eye Contact: Rinse cautiously for several minutes with water, remove contact lenses, keep rinsing, and seek medical attention
Skin Contact: Remove contaminated clothing, wash thoroughly with soap and water, seek medical help if irritation persists
Inhalation: Move to fresh air, keep at rest, administer oxygen if breathing trouble occurs, get medical advice right away
Ingestion: Rinse mouth out, get immediate medical assistance, do not induce vomiting unless instructed by health personnel
Most important symptoms: Irritation, possible allergic reactions, respiratory difficulties, nausea, headache
Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray
Unsuitable Extinguishing Media: Full water jet may spread material
Specific Hazards: Toxic fumes like NOx, HBr, CO released during combustion
Protective Equipment: Firefighters should wear approved self-contained breathing apparatus and full protective gear
Special Procedures: Keep containers cool with water spray from safe distance, control runoff for environmental protection
Personal Precautions: Wear gloves, goggles, face protection, remove ignition sources, ventilate area
Environmental Precautions: Prevent entry into drains, soil, and waterways, notify authorities in case of significant spill
Methods for Clean-up: Collect using inert absorbent, place in a sealed compatible container, wash surfaces with detergent, ventilate area
Other Precautions: Dispose of cleanup materials as hazardous waste according to regional regulations
Handling: Avoid dust formation, use in chemical fume hood, handle with chemical-resistant gloves, avoid direct inhalation and skin contact
Storage: Store in tightly closed, clearly labeled containers, protect against moisture and light, keep in cool, well-ventilated area, segregate from acids, bases, and reducing agents
Engineering Controls: Operate in chemical fume hood or with local exhaust ventilation, eyewash and safety shower nearby
Personal Protective Equipment: Safety glasses with side shields or goggles, disposable gloves (nitrile recommended), laboratory coat, approved respirators if exposure limits risk is high
Hygiene Measures: Wash thoroughly after handling, do not eat or drink during work, avoid all unnecessary exposure
Exposure Limits: No OSHA/ACGIH exposure limits specific for 4-Nitrobromobenzene; minimize exposure as a standard precaution
Appearance: Yellow to orange crystalline solid
Odor: Faint, aromatic
Melting Point: Around 125-129°C (257-264°F)
Boiling Point: 306°C (582°F)
Solubility: Insoluble in water, soluble in organic solvents (ethanol, ether, benzene)
Relative Density: About 1.79 g/cm³
Vapor Pressure: Low at room temperature
Partition Coefficient (log Kow): Estimated moderate, may bioaccumulate
Flash Point: Not easily flammable; take precautions with fine dust
Auto-ignition Temperature: Not established
Chemical Stability: Stable if stored in dry, cool conditions away from heat and direct sunlight
Reactivity: May react with strong acids, strong bases, or reducing agents
Hazardous Decomposition Products: Nitrogen oxides, bromine compounds, carbon monoxide, carbon dioxide
Conditions to Avoid: Excessive heat, moisture, incompatible chemicals
Polymerization: Not known to occur under normal conditions
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; LD50 (oral, rat) ~700 mg/kg
Skin Corrosion/Irritation: Causes mild to moderate irritation
Serious Eye Damage/Irritation: May cause burning, redness, blurred vision
Respiratory Effects: Breathing dust or fumes may cause coughing, wheezing, shortness of breath
Chronic Exposure: Long-term effects not fully studied, but prolonged exposure may cause organ toxicity
Carcinogenicity/Mutagenicity: Data insufficient, not classified as known human carcinogen
Target Organ Effects: Liver, kidneys, central nervous system in high-dose settings
Sensitization: Rarely reported, but possible with repeated exposure
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments
Persistence/Degradability: Expected to persist and accumulate in soil/water; slow breakdown in natural settings
Bioaccumulation: Log Kow suggests potential for bioaccumulation in aquatic species
Mobility in Soil: Limited mobility in soil due to limited water solubility
Other Adverse Effects: Avoid releases to the environment; follow best practices to prevent contamination
Product Disposal: Treat as hazardous waste; follow local, state, federal, and national regulations for chemical disposal
Contaminated Packaging: Dispose of in accordance with regulations, ensure containers are fully empty and triple-rinsed if possible
Recommended Method: Use licensed hazardous waste disposal contractor; incineration preferred for complete destruction
UN Number: 2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 4-Nitrobromobenzene)
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III (minor danger)
Special Precautions for Transport: Protect containers from damage, ensure clear hazard labeling, comply with local, regional, national, and international regulations
US Regulations: TSCA listed, subject to SARA 313 reporting for toxic chemicals, OSHA hazardous chemical
EU Regulations: Registered under REACH, requires appropriate hazard labeling (GHS/CLP)
Workplace Exposure: Companies must maintain safety training, provide MSDS to staff, and conduct risk assessments
Other Regulations: Adhere to all environmental, health, and safety guidelines for chemical management, storage, and disposal under respective local authority frameworks
