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Product Name: 4-Nitrobenzoyl Chloride
Chemical Formula: C7H4ClNO3
Synonyms: p-Nitrobenzoyl Chloride, 1-Chloro-4-nitrobenzene-1-one
CAS Number: 122-04-3
Recommended Use: Laboratory chemicals, chemical synthesis
Supplier: Industrial chemical suppliers, specialized laboratory providers
Emergency Contact Number: Refer to local regulations and supplier documentation
Address: Obtained from supplier data
Classification: Corrosive to eyes, skin, and respiratory tract; Harmful by inhalation, ingestion, or skin absorption
Health Hazards: Severe irritation to eyes and skin; May cause burns; Respiratory system irritation; Risk of sensitization after skin contact
Environmental Hazards: Toxic to aquatic life; Persistence in waterways possible if released
Label Elements: Skull and crossbones symbol; Corrosive pictogram
Signal Word: Danger
Precautionary Statements: Avoid inhalation of dust, vapors, or direct contact; Use proper protective equipment; Do not release to the environment
Hazard Statements: Causes severe skin burns and eye damage; Harmful if swallowed or inhaled
Chemical Name: 4-Nitrobenzoyl Chloride
Concentration: ≥98%
Impurities: Trace hydrochloric acid, nitrobenzene derivatives
Other Ingredients: No significant hazardous additives
Molecular Weight: 185.57 g/mol
Inhalation: Remove victim to fresh air; Seek medical attention immediately if symptoms develop; Administer oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing; Wash affected area thoroughly with soap and water for at least 15 minutes; Seek immediate medical assistance
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting upper and lower eyelids frequently; Obtain emergency medical help
Ingestion: Do not induce vomiting; Rinse mouth thoroughly; Give plenty of water if conscious; Get urgent medical attention
Symptoms of Exposure: Burning sensation, cough, shortness of breath, rash, redness, pain, eye watering
Medical Attention and Special Treatment: Symptomatic and supportive care based on degree of exposure
Suitable Extinguishing Media: Use dry sand, carbon dioxide, or alcohol-resistant foam; Water spray for large fires
Specific Hazards Arising from Chemical: Releases corrosive and toxic gases such as hydrogen chloride and nitrogen oxides during combustion
Protection for Firefighters: Wear self-contained breathing apparatus and full protective clothing; Prevent runoff from entering drains or waterways
Special Procedures: Move containers away from fire; Cool containers with water spray; Approach upwind to avoid hazardous vapors
Personal Protection: Evacuate non-essential personnel; Ventilate area; Wear chemical-resistant gloves, safety goggles, and protective suit
Environmental Precautions: Prevent further leakage or spillage if safe to do so; Avoid release to the environment; Notify authorities in case of major release
Methods for Clean Up: Absorb spill with inert material such as sand or earth; Place in closed, labeled container for proper disposal; Clean surface thoroughly to remove residues
Precautions During Handling: Use only in a well-ventilated area with appropriate exhaust; Avoid contact with eyes, skin, and clothing; Do not breathe dust, fumes, or vapors
Hygiene Practices: Wash hands thoroughly after handling; Do not eat, drink or smoke around this material; Change contaminated clothing immediately
Storage Conditions: Keep container tightly closed in a cool, dry, well-ventilated place away from moisture, strong bases, and oxidizers; Store in original packaging or approved corrosion-resistant containers
Incompatibilities: Strong bases, strong oxidizers, water, alcohols, amines
Storage Temperature: Ambient temperature, away from direct sunlight and sources of ignition
Engineering Controls: Operate in a chemical fume hood; Provide eyewash and safety shower in immediate work area
Respiratory Protection: Use NIOSH-approved respirator if airborne concentrations are above limits or during spill cleanup
Eye Protection: Chemical safety goggles or face shield
Hand Protection: Wear chemical-resistant gloves such as nitrile or neoprene
Skin Protection: Use lab coat, chemical-resistant apron, and closed footwear
Occupational Exposure Limits: No established OSHA or ACGIH exposure limits; Minimize exposure using best industrial hygiene practices
Environmental Controls: Prevent vapors or particulate release to ambient environment; Use scrubbers or filters if required by local legislation
Appearance: Pale yellow to beige crystalline solid or powder
Odor: Pungent, irritating
Melting Point: 75-78°C
Boiling Point: 251°C
Flash Point: Not readily flammable
Solubility: Reacts with water to form 4-nitrobenzoic acid and hydrogen chloride; Soluble in organic solvents (ether, chloroform)
Density: ~1.5 g/cm3
Vapor Pressure: Negligible at room temperature
pH: Not applicable
Auto-ignition Temperature: Data not readily available
Evaporation Rate: Not applicable
Stability: Stable under recommended storage conditions; Decomposes on contact with moisture
Hazardous Reactions: Violent reaction with water, alcohols, strong bases; Forms toxic and corrosive gases
Materials to Avoid: Moisture, water, amines, alcohols, oxidizing agents, bases
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, 4-nitrobenzoic acid
Polymerization: Will not occur under normal storage and handling conditions
Acute Toxicity: Harmful if inhaled, swallowed, or absorbed through skin; Irritation or burning sensation at the site of exposure
Routes of Exposure: Eyes, skin, inhalation, ingestion
Symptoms: Severe irritation, redness, burns in eyes and on skin; Cough, throat pain, difficulty breathing for inhaled vapors; Abdominal pain for ingestion
Chronic Effects: Prolonged or repeated exposure may result in dermatitis, respiratory problems, and possible sensitization
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Sensitization: May cause allergic skin reaction in sensitive individuals
Mutagenicity/Teratogenicity: No data available
Ecotoxicity: Toxic to aquatic organisms; Harmful effects on fish, invertebrates, and microorganisms at low concentrations
Persistence and Degradability: Decomposes slowly; Not readily biodegradable
Bioaccumulative Potential: Potential for bioaccumulation in aquatic organisms if released
Mobility in Soil: Low mobility; Strongly adsorbs to organic matter in soils
Other Adverse Effects: Degradation products may cause environmental harm; Avoid release to water systems
Waste Treatment Methods: Dispose of material as hazardous waste through licensed facility; Do not drain to sewer or natural environment
Container Disposal: Decontaminate and dispose of containers in accordance with local, regional, and national laws
Precautions for Disposal: Wear full protective equipment during waste handling; Store waste in tightly closed, labeled containers
Recommended Disposal: Incineration in an approved chemical incinerator with afterburner and scrubber; Consult environmental authorities
UN Number: UN 3261
Proper Shipping Name: Corrosive Solid, Acidic, Organic, N.O.S. (contains 4-Nitrobenzoyl Chloride)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Marine Pollutant: Yes, potential harm to aquatic flora and fauna
Special Precautions: Transport according to regulations; Ensure containers are secure and clearly labeled; Emergency response guide number as specified by local authorities
Labels Required: Corrosive, Marine pollutant
TSCA Status: Listed
REACH Status: Subject to registration or notification in EU jurisdiction
US OSHA: Classified hazardous; Requires communication of hazards under OSHA Hazard Communication Standard
SARA Title III: Listed under Section 313 for reporting of toxic releases; Check exact reporting thresholds
WHMIS (Canada): Corrosive material; Other classification based on Canadian guidelines
Other International Regulations: Transport, workplace exposure, and environmental regulations may apply; Confirm with local and national authorities for handling, storage, and use
Labeling Requirements: Signal word "Danger," hazard pictograms for corrosive and toxic effects, precautionary and hazard statements per GHS guidelines
