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Chemical Name: 4-Nitrobenzamide
Synonyms: para-Nitrobenzamide, p-Nitrobenzamide
CAS Number: 619-01-2
Recommended Use: Laboratory chemical, intermediate for synthesis
Manufacturer Information: Manufacturer’s name and contact details provided on packaging and product datasheet
Emergency Phone Number: Provided by manufacturer/distributor for 24-hour response
Product Identifier: Distinct labeling and lot number for tracking purposes
Hazard Classification: Not classified as highly hazardous but requires careful handling due to harmful effects on health
GHS Label Elements: Warning signal word; exclamation mark pictogram
Hazard Statements: May cause acute toxicity by inhalation, skin contact, or ingestion; can cause irritation to eyes, respiratory tract, and skin
Precautionary Statements: Avoid breathing dust; wear protective gloves; wash hands thoroughly after handling; if exposed or concerned, seek medical attention
Routes of Exposure: Inhalation, ingestion, contact with skin or eyes
Other Hazards: Generates toxic fumes on ignition or during decomposition
Substance: 4-Nitrobenzamide
Chemical Formula: C7H6N2O3
Purity: ≥ 98% (typical for laboratory use)
Impurities: Minimal, not expected to contribute to hazards at listed purity
Molecular Weight: 166.14 g/mol
Component Percentages: 100% 4-Nitrobenzamide
General Guidance: Remove person from exposure, administer first aid in safe area
Inhalation: Move to fresh air, support breathing with oxygen if needed, seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, wash with soap and water for several minutes, get medical help for irritation or burns
Eye Contact: Rinse cautiously with water for at least 15 minutes, lift eyelids to ensure flushing, seek medical care for lasting effects
Ingestion: Rinse mouth, don’t induce vomiting without medical advice, obtain medical aid promptly
Symptoms: Can include coughing, headache, skin redness or blistering, stomach pain, nausea
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides and carbon oxides
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective clothing
Specific Hazards: Dust can form explosive mixtures with air if fine particles disperse
Firefighting Instructions: Use water spray to cool containers, keep runoff from entering waterways
Special Procedures: Evacuate area, avoid inhaling smoke or combustion vapors
Personal Precautions: Evacuate unnecessary personnel, ventilate area, use recommended personal protective equipment
Environmental Precautions: Prevent entry into drains, surface water, or soil
Containment Methods: Avoid dispersal of dust; sweep up with non-sparking tools, collect in sealed containers for disposal
Cleanup Procedures: Clean area with water after removal, avoid dry sweeping to limit dust generation
Reporting: Notify relevant environmental authorities as required by regulations
Handling: Avoid contact with skin, eyes, and clothing; avoid inhaling dust; handle in well-ventilated area or fume cupboard
Personal Hygiene: Wash thoroughly after handling; avoid eating or drinking in work area
Storage Conditions: Store in tightly sealed container, away from incompatible substances (e.g. strong oxidizers), in a dry, cool, and well-ventilated setting
Storage Temperature: Recommended ambient room temperature; protect from heat and direct sunlight
Segregation: Keep away from food, drink, and animal feed
Exposure Limits: No specific occupational exposure limits established; minimize exposure as part of good laboratory practice
Engineering Controls: Use chemical fume hoods, local exhaust ventilation to control airborne concentrations
Personal Protective Equipment: Safety goggles or face shield, chemical-resistant gloves, laboratory coat
Respiratory Protection: Use approved respirators for dusty operations or if ventilation is inadequate
Environmental Controls: Routine, monitored safe disposal of waste and runoff
Appearance: Pale yellow crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH: Neutral
Melting Point/Freezing Point: 193–195°C
Boiling Point: Decomposes before boiling
Flash Point: Not established
Evaporation Rate: Not applicable (solid at room temperature)
Flammability: Not easily combustible but forms combustive dust when dispersed
Vapor Pressure: Negligible
Vapor Density: Not applicable
Solubility: Slightly soluble in water; more soluble in organic solvents such as ethanol and acetone
Partition Coefficient (n-octanol/water): No data available
Decomposition Temperature: Above 195°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts vigorously with strong oxidizing agents
Possibility of Hazardous Reactions: Prolonged heating leads to decomposition and possible emission of toxic gases
Conditions to Avoid: Elevated temperature, open flames, sparking, strong sunlight
Incompatible Materials: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, other unidentified toxic fumes
Acute Toxicity: Harmful by ingestion, inhalation, or skin contact; limited data suggest oral LD50 (rat) > 2000 mg/kg
Skin Sensitization: Can cause irritation; not reported as a known sensitizer
Eye Effects: Causes irritation, redness, pain
Chronic Toxicity: Prolonged exposure may affect organ function and health
Mutagenicity/Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Reproductive Effects: No data indicating reproductive toxicity
Target Organs: Respiratory tract, skin, eyes
Ecotoxicity: Toxic to aquatic life with long-lasting effects; data suggest potential for harm if released into water bodies
Persistence and Degradability: Limited evidence for rapid biodegradation; may persist in soil or sediments
Bioaccumulation Potential: Not expected to bioaccumulate based on structure and properties
Mobility in Soil: Low to moderate due to limited solubility in water
Other Effects: Spillages may harm flora and fauna in the immediate surroundings
Waste Treatment Methods: Dispose by incineration or through licensed chemical waste contractors
Contaminated Packaging: Rinse thoroughly before disposal; regard packaging as hazardous waste
Disposal Restrictions: Do not release into drains, surface water, or soil
Regulatory Disposal Requirements: Comply with federal, state, and local environmental requirements
UN Number: Not classified as a dangerous good by transport regulations
UN Proper Shipping Name: Not regulated
Transport Hazard Class: No specific hazard class; handle as laboratory chemical
Packing Group: Not applicable
Environmental Hazards: Not specifically regulated, though harmful to aquatic environments
Special Precautions: Use well-sealed containers; prevent dust formation during transport; avoid heat or direct sunlight
OSHA: Not specifically regulated as hazardous under OSHA standards, but general safety controls advised
SARA Title III: Not listed as an extremely hazardous substance
TSCA Status: Listed in the US Toxic Substances Control Act (TSCA) Inventory
REACH (Europe): Registered or pre-registered under relevant annexes
DSL (Canada): Included on Domestic Substances List
Other Regulations: Local, state, and federal regulations may still require reporting or special control procedures
