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Product Name: 4-Nitrobenzaldehyde
Chemical Name: p-Nitrobenzaldehyde
CAS Number: 555-16-8
Molecular Formula: C7H5NO3
Molecular Weight: 151.12 g/mol
Synonyms: Para-nitrobenzaldehyde, 4-formylnitrobenzene
Recommended Uses: Laboratory reagent, intermediate in chemical synthesis
Supplier Details: Commonly available from scientific supply companies, contact details available on company invoices
Emergency Contact: Refer to standard regional poison control numbers or local fire brigade
GHS Classification: Acute Toxicity Oral: Category 4; Eye Irritation: Category 2A; Skin Irritation: Category 2
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Major Health Effects: Direct skin contact may lead to redness, inflammation, or rash; eye exposure can cause burning, redness, and watering; inhaling dust or fumes can bring on throat irritation or respiratory symptoms
Environmental Impact: May be hazardous to aquatic environments; spillages need to be handled quickly to cut risk to wildlife and water bodies
Routes of Exposure: Eye and skin contact, ingestion, inhalation of dust or vapor
Precautionary Statements: Wear protective clothing; avoid breathing dust; wash hands thoroughly after use; take measures to prevent environmental release
Chemical Identity: 4-Nitrobenzaldehyde
Purity: Usually supplied at over 98% pure
Impurities: Typical impurities include ortho and meta-substituted isomers
Component Percent: 4-Nitrobenzaldehyde: 98-100%; Other trace materials below 2%
Formula: C7H5NO3
Physical Appearance: Pale yellow crystalline solid
Inhalation: Remove person to fresh air; seek medical advice if symptoms like coughing persist or worsen; provide oxygen if breathing becomes labored
Skin Contact: Immediately wash affected area with plenty of running water and soap; remove contaminated clothing; monitor for rash or burns; get medical advice if irritation continues
Eye Contact: Flush eyes gently for at least 15 minutes with running water, pulling eyelids apart; do not let patient rub eyes; seek medical examination
Ingestion: Rinse mouth thoroughly, keep individual calm; do not induce vomiting; seek medical attention without delay
Acute Symptoms: Stomach pain, nausea, possible headaches or dizziness
Advice to Doctor: Treat based on symptoms and supportive care; no known antidote
Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide; avoid water jets on powder spills
Hazardous Combustion Products: Burning releases toxic oxides of nitrogen, carbon monoxide, and possibly hydrogen cyanide
Specific Hazards: Dust dispersion can result in flammable or explosive mixture under right conditions
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Move containers from fire zone if possible; avoid inhaling fumes; cool nearby containers with water spray
Decomposition Temperature: Begins to break down releasing vapors over 200°C
Personal Precautions: Avoid dust formation, ventilate area, use recommended personal protective equipment; prevent contact with skin and eyes
Environmental Precautions: Prevent material from entering drains, surface water, and soil
Cleanup Methods: Collect spilled material with vacuum or damp cloth; sweep with care to avoid dust; seal waste in appropriate container for disposal
Disposal: Dispose of contaminated items using regulations governing hazardous waste; thorough area cleaning to prevent residue
Handling: Avoid creating dust clouds; use within chemical fume hoods or with local exhaust if working with powder in bulk; never eat or drink in storage areas; wash hands after handling
Storage: Store in tightly-closed containers in a cool, dry, well-ventilated place away from incompatible substances like oxidizers or acids; avoid sources of ignition; do not store near foodstuffs
Incompatibility: Strong reducing agents, alkalis, oxidizers may cause violent reactions
Exposure Limits: No established OSHA or ACGIH exposure limit; keep exposure as low as possible by standard chemical hygiene practices
Engineering Controls: Use chemical fume hood; provide local exhaust in areas where dust is generated
Personal Protection Equipment (PPE): Safety glasses with side shields, lab coats, chemical-resistant gloves (nitrile or neoprene), closed shoes; for large-scale handling, use face mask or respirator fitted with appropriate cartridge
Hygiene Measures: Thorough hand and face washing after use; do not touch face or eyes unless hands are washed; remove contaminated clothing as soon as possible
Environmental Controls: Fume hood vented outside; avoid atmospheric or water contamination
Appearance: Pale yellow crystalline solid
Odor: Faint, aromatic, slightly almond-like
Melting Point: Around 106-108°C
Boiling Point: Not well-defined (may decompose before boiling)
Solubility: Poor in water; soluble in organic solvents like ethanol, ether, acetone
Density: About 1.3 g/cm³
Vapor Pressure: Very low at room temperature
pH: Not applicable in solid form
Partition Coefficient (log Pow): Estimated around 1.7
Flash Point: Above 110°C (closed cup)
Autoignition Temperature: Not specifically documented, likely above 200°C
Explosive Properties: No documented explosive hazard under common handling
Oxidizing Properties: Not oxidizing under standard conditions
Chemical Stability: Stable under normal storage and handling conditions
Possibility of Hazardous Reactions: Risk of violent reaction with strong oxidizing agents, strong bases, and reducing agents
Conditions to Avoid: Excessive heat, sources of ignition, direct sunlight, moisture
Incompatible Materials: Strong alkalis, strong oxidizers, reducing agents, acids
Decomposition Products: Toxic gases may include nitrogen oxides, carbon monoxide, and carbon dioxide
Polymerization: Will not occur under recommended handling
Likely Routes of Exposure: Eye, skin, ingestion, inhalation
Acute Toxicity: Oral LD50 (rat): estimated at 640 mg/kg; moderate toxicity by ingestion
Skin Corrosion/Irritation: May cause redness, dryness, discomfort on contact
Eye Damage/Irritation: Causes eye irritation; redness and tearing possible
Respiratory Effects: Inhalation of dust may irritate upper airways, cough, sneezing
Chronic Effects: Repeated contact may lead to dermatitis or respiratory sensitization in susceptible individuals
Carcinogenicity: No evidence of carcinogenicity in humans or animals
Mutagenicity: No known genetic impact from short-term or long-term exposure
Other Data: No sufficient long-term animal studies published at time of writing; always treat as potentially harmful
Aquatic Toxicity: Harmful to aquatic organisms; may cause long-term effects in the aquatic environment
Persistence and Degradability: Not rapidly biodegradable, persists in soil and water for extended periods
Bioaccumulative Potential: Limited, but possible accumulation in aquatic species over time
Mobility in Soil: Low mobility due to moderate water solubility and partition coefficient
Other Adverse Effects: Spillage or uncontrolled disposal can lead to toxicity in fish, invertebrates, or soil bacteria; always prevent release into environment
Waste Disposal: Dispose as hazardous chemical waste following local, regional, or national regulations
Container Disposal: Decontaminate empty containers before discarding, or send to chemical waste disposal
Prevent Release: Do not pour leftover material into drains or natural waterways
Recommended Method: Use licensed chemical incineration or burial at permitted hazardous waste facility
Regulatory Codes: Check local waste codes for organic hazardous chemicals for compliance
UN Number: 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains 4-nitrobenzaldehyde)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III (Substances presenting low danger)
Label Requirements: Toxic symbol mandatory on shipping packages
Special Precautions: Prevent package damage during transport; track all movements of container; restrict access to trained handlers
Air Transport: Follow IATA guidelines for toxic, non-bulk shipments
Sea/Rail Transport: Refer to IMDG and ADR compliance for international shipments
Emergency Response Guide: Consult local regulations for spill or leak emergency
Regulatory Status: Restricted for sale and use in general consumer markets; permitted for scientific, analytical or industrial use under conditions
GHS Label Elements: Covered by hazard pictogram, warning word, and detailed response instructions
R-phrases: Harmful if swallowed; irritating to eyes and skin
S-phrases: Avoid contact with skin, keep away from sources of ignition, do not discharge into drains
Inventory Listing: Appears in the TSCA inventory (USA), EINECS in the EU, and similar regulations
Other Legal Considerations: Occupational exposure standards may apply for workplaces; laboratory and industrial users need awareness of chemical hygiene and environmental controls; all documentation and safe-use protocols should be up to date
