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Product Name: 4-Nitro-2-Methoxyaniline
Chemical Formula: C7H8N2O3
Other Names: 2-Methoxy-4-nitroaniline; p-Nitro-o-anisidine
CAS Number: 97-52-9
Use: Dye intermediate, research chemical
Supplier Contact: Address, phone, email available through purchasing records
Emergency Phone Number: Refer to local poison control or chemical safety authority
Hazard Class: Acute toxicity (oral, inhalation, dermal), skin and eye irritant, suspected mutagenic effects
Symbol: Skull and crossbones, exclamation mark
Signal Word: Danger
Hazard Statements: Harmful if swallowed or in contact with skin, causes skin and eye irritation, suspected of causing genetic defects, toxic to aquatic life
Precautionary Statements: Do not breathe dust or vapors, avoid release to environment, wash hands thoroughly after handling, wear gloves and eye protection
Chemical Name: 4-Nitro-2-Methoxyaniline
CAS Number: 97-52-9
Concentration: ≥98% (technical grade)
Impurities: Trace anilines & mono-nitro by-products (from synthesis process), may contribute to hazard
Inhalation: Move the person to fresh air, provide oxygen if breathing is difficult, seek medical attention immediately
Skin Contact: Remove contaminated clothing, wash with soap and plenty of water for at least 15 minutes, call a physician right away
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing and consult eye doctor
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, seek medical advice immediately, show chemical label if possible
Most Important Symptoms: Nausea, headache, skin redness, irritation, dizziness, risk of more severe chemical poisoning from extended exposure
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, alcohol-resistant foam
Hazards from Combustion: Toxic gases like nitrogen oxides, carbon monoxide can form in a fire
Firefighter Protection: Full protective gear and self-contained breathing apparatus, avoid inhaling combustion products
Other Advice: Prevent fire water run-off from entering drains or water sources, cool barrels with water spray if safe
Personal Precautions: Ventilate area, avoid breathing dust or vapors, wear recommended respiratory protection and gloves, evacuate unprotected personnel
Environmental Precautions: Prevent substance entry into soil, sewers, drains, and watercourses due to risk of long-term pollution
Clean-Up Procedure: Sweep up without creating dust, shovel into labeled chemical waste container, wash spill site thoroughly after material pickup, dispose as hazardous waste according to local rules
Handling: Use with adequate ventilation, avoid contact with skin, eyes, and clothing, wear suitable gloves, goggles, and lab coat, avoid inhaling dust or fumes, practice safe chemical hygiene
Storage: Store in a tightly closed, properly labeled container in a cool, dry, well-ventilated area away from incompatible substances (oxidizing agents, acids), segregate from food and drink, restrict access to trained personnel only
Special Precautions: Wash hands thoroughly after use, minimize quantity kept on hand, consider lockable storage for high-toxicity chemicals
Engineering Controls: Handle in a chemical fume hood, use local exhaust to minimize airborne concentrations
Personal Protective Equipment: Protective nitrile gloves, lab coat, chemical safety goggles or face shield, approved respirator if airborne exposure may occur
Workplace Exposure Limits: No established OSHA or ACGIH limits, minimize exposure as much as possible
Hygiene Measures: Do not eat, drink, or smoke during use, wash hands before breaks and after handling, keep contaminated clothing out of workplace laundry cycle
Appearance: Orange to brownish crystalline powder
Odor: Slight, characteristic aromatic
Molecular Weight: 168.15 g/mol
Melting Point: 143–146 °C
Boiling Point: Not available
Solubility: Insoluble in water, soluble in ethanol, ether, and organic solvents
Vapor Density: Not available
Partition Coefficient (octanol/water): No data, likely moderate due to aromatic structure
pH: Not applicable
Other Properties: Stable under standard conditions, may darken on light exposure
Chemical Stability: Stable in closed container at room temperature under recommended storage
Reactivity: No dangerous reactions predicted with normal use
Conditions to Avoid: Heat, open flame, UV light exposure
Incompatible Materials: Strong acids, strong oxidizing agents, reducing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, toxic vapors
Polymerization: Will not occur
Acute Toxicity: Harmful if swallowed or inhaled, toxic in contact with skin, suspected mutagenic effect
Skin Corrosion: May cause irritation, redness, itching
Eye Damage: Causes moderate to severe irritation, risk of lasting effects
Inhalation: Irritating to respiratory tract, drowsiness, dizziness possible with high exposure
Chronic Effects: Possible risk of anemia, liver or kidney damage after prolonged exposure, insufficient data on carcinogenicity
Mutagenicity: Suspected based on structural analogs and limited test data
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Target Organs: Blood, liver, kidneys
Toxicity to Aquatic Organisms: Harmful to aquatic life, chronic effects on fish and invertebrates suspected
Persistence and Degradability: Poorly biodegradable, may persist in natural environments
Bioaccumulation Potential: Unlikely but some risk due to aromatic ring structure
Mobility in Soil: Limited movement, binds to organic matter
Other Adverse Effects: Releases anilines and nitroaromatics, compounds with potential toxicity to aquatic and terrestrial life, importance of limiting environmental release
Waste Treatment Methods: Dispose of as hazardous chemical waste under federal, state, and local regulations
Container Handling: Triple rinse containers before disposal, label appropriately
Incineration: Use approved chemical incinerator with afterburner and scrubber to minimize hazardous air emissions
Disposal Prohibitions: Do not dispose to drains, surface water, or soil, do not mix with household waste
Hazardous Waste Code: Contact local authorities for classification and packaging advice
UN Number: UN2811 – Toxic solid, organic, n.o.s. (contains aromatic amine, nitro derivative)
Class: 6.1 Toxic substances
Packing Group: III (moderate hazard)
Label: Toxic, avoid direct contact
Special Transport Notes: Package securely, use secondary containment, notify carrier of chemical hazards, documentation should accompany shipment
US TSCA: Listed or subject to reporting rules
EU REACH: Substance may require registration for import or use in the EU
SARA Title III: Chemical may be subject to section 313 reporting due to potential environmental hazard
Other Country Regulations: Refer to local chemical safety authorities, restrictions may apply based on toxicity, mutagenicity, and aquatic effects
Workplace Safety: Training and documentation required under OSHA and similar national standards due to moderate acute toxicity and exposure risk, periodic risk assessment recommended for users
