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Material Safety Data Sheet for 4'-Chloro-3,4-Dihydroxybenzophenone

Identification

Product Name: 4'-Chloro-3,4-Dihydroxybenzophenone
Synonyms: 2,4-Dihydroxy-4'-chlorobenzophenone
Chemical Formula: C13H9ClO3
CAS Number: 85-19-8
Recommended Use: Research, laboratory purposes, chemical synthesis
Manufacturer: Chemical suppliers and distributors with reliable quality control
Contact Information: Refer to supplier data for address, emergency numbers, and responsible staff

Hazard Identification

GHS Classification: Irritant (Eye, Skin), Harmful if swallowed
Signal Word: Warning
Hazard Statements: Causes eye irritation, may cause skin and respiratory tract irritation, harmful if swallowed
Pictograms: Exclamation mark indicates moderate health hazard
Precautionary Statements: Avoid breathing dust, wash hands thoroughly, do not eat or drink while handling, use only with adequate ventilation
Physical Hazards: Not considered combustible, but fine particles can cause dust explosion risk

Composition / Information on Ingredients

Chemical Name: 4'-Chloro-3,4-Dihydroxybenzophenone
CAS Number: 85-19-8
Concentration: Typically ≥ 98% pure
Impurities: Low levels of related phenolic byproducts possible, check batch analysis
Additives: None known

First Aid Measures

Eye Contact: Rinse cautiously with water, remove contact lenses if present, continue rinsing for at least 15 minutes, seek medical advice if irritation persists
Skin Contact: Wash affected area with soap and water, remove contaminated clothing, get medical attention if symptoms develop
Inhalation: Move to fresh air, keep at rest, provide artificial respiration if breathing is difficult, call a physician if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting without medical direction, seek immediate medical attention
Notes for Physicians: Treat symptomatically based on patient's condition

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, CO2, dry chemical powder, foam
Hazards from Combustion: May form toxic fumes of hydrochloric acid, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Wear full protective gear, self-contained breathing apparatus
Special Procedures: Evacuate area, avoid inhalation of smoke or gases, cool fire-exposed containers with water spray

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, dust mask or respirator, protective lab coat
Spill Containment: Ventilate area, prevent dust formation, avoid raising dust clouds
Cleanup Methods: Sweep up carefully, place in labeled waste container, avoid water runoff, decontaminate area with appropriate cleaning agents
Environmental Precautions: Prevent contaminant from entering drains, surface water, or soil

Handling and Storage

Handling Practices: Work in well-ventilated fume hood, use PPE, avoid breathing dust, avoid contact with skin and eyes, keep containers tightly closed when not in use
Storage Conditions: Store in a cool, dry place, away from direct sunlight, keep away from incompatible materials (strong oxidizers, acids, alkalis), use chemical-resistant containers
Incompatible Materials: Avoid storage near strong acids or bases and oxidizing agents
Hygiene: Wash hands after handling, refrain from eating or drinking in storage and handling areas

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH exposure limits for this specific compound
Engineering Controls: Use chemical fume hood, dust extraction systems, general dilution ventilation
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene recommended), safety glasses with side shields or goggles, lab coat or chemical-resistant apron, NIOSH-approved dust respirator if exposure limit could be exceeded
Special Safety Procedures: Emergency eyewash station and safety shower in immediate access

Physical and Chemical Properties

Physical State: Crystalline solid
Color: Off-white to light yellow
Odor: Odorless or faint chemical scent
Molecular Weight: Approximately 248.67 g/mol
Melting Point: Around 205-208°C
Boiling Point: Data not available, decomposes before boiling
Solubility: Slightly soluble in water, readily soluble in organic solvents like ethanol, acetone, ether
Vapor Pressure: Negligible at room temperature
Flash Point: Data not available
pH: Not applicable (insoluble in water)
Partition Coefficient: Log Pow data not available
Density: Approximately 1.4–1.5 g/cm³

Stability and Reactivity

Chemical Stability: Stable under normal laboratory conditions
Conditions to Avoid: Exposure to moisture, strong heat sources, light
Incompatible Materials: Strong oxidizers, strong acids, alkalis
Hazardous Decomposition Products: Hydrochloric acid gas, CO, CO2 under fire or extreme heat
Polymerization: No risks of hazardous polymerization reported

Toxicological Information

Acute Toxicity: Limited data, may cause low to moderate toxicity via ingestion, data on LD50 not widely published
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Symptoms: Irritation to mucous membranes, possible stomach discomfort, redness at contact sites
Chronic Toxicity: Long-term effects not fully characterized for this compound
Sensitization: Not known to be a skin or respiratory sensitizer
Carcinogenicity/Mutagenicity: No classification as carcinogen by IARC, NTP, or OSHA
Medical Conditions Aggravated: Pre-existing skin, respiratory, or eye conditions may be aggravated upon exposure

Ecological Information

Ecotoxicity: Detailed ecotoxicity data not available, potential risk to aquatic environments not well documented
Mobility in Soil: Expected to have limited mobility due to low solubility
Persistence and Degradability: Contains aromatic rings, may persist in environment, slow to degrade
Bioaccumulation Potential: Data lacking, precaution advised for significant releases
Other Harmful Effects: No specific evidence for ozone depletion, photochemical smog, or endocrine disruption

Disposal Considerations

Waste Treatment Methods: Dispose of solid waste via permitted chemical waste incineration or landfilling in accordance with local, regional, and national regulations
Container Disposal: Rinse and triple-clean containers before recycling or discarding, remove all labels
Special Precautions: Do not release into environment or municipal wastewater streams
Consultation: Contact certified chemical waste disposal contractor for bulk material

Transport Information

UN Number: Not classified under typical hazardous chemical UN numbers
Shipping Name: Chemical, not otherwise specified (if not regulated)
Transport Hazard Class: Non-regulated
Packing Group: Not assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for User: Ship in chemical-resistant, sealed containers with clear hazard labeling, avoid damage and breakage
Transport Regulations: Follow all applicable DOT, IATA, IMDG requirements for laboratory chemicals

Regulatory Information

TSCA (USA): Listed
DSL/NDSL (Canada): Check product documentation for specific inclusion
EINECS/ELINCS (EU): Registered or pre-registered
SARA Title III: Not subject to reporting under Sections 302, 304, 313
California Prop 65: Not listed as a substance known to cause cancer or reproductive toxicity
Labeling Requirements: Provide hazard warning consistent with GHS, maintain clear documentation of hazard class and emergency contacts
Other Regulations: Local and national regulations for storage, handling, waste, import/export must be observed as chemical safety policies require