© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: 4-Bromophenol
Chemical Formula: C6H5BrO
Molecular Weight: 173.01 g/mol
Chemical Family: Phenols, Brominated aromatic compounds
Synonyms: p-Bromophenol, para-Bromophenol, 4-Bromo-1-hydroxybenzene
CAS Number: 106-41-2
Recommended Uses: Laboratory reagent, chemical synthesis intermediate
Manufacturer Contact: Refer to supplier or distributor label for emergency phone numbers and contact details
GHS Classification: Acute Toxicity - Oral (Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust; Wash hands thoroughly after handling; Wear protective gloves, clothing, and eye protection
Potential Health Effects: Inhalation may irritate respiratory tract; skin contact causes redness or inflammation; direct eye contact may result in pain, redness, and blurred vision; ingestion may cause headache, nausea, or abdominal pain
Chronic Effects: Prolonged or repeated skin exposure may cause dermatitis; no evidence of carcinogenicity in available studies
Chemical Name: 4-Bromophenol
Percentage: >98% (typical purity for laboratory use)
Impurities: Trace brominated phenols (<2%)
Hazardous Ingredients: 4-Bromophenol is classified as hazardous according to OSHA and GHS criteria
EC Number: 203-397-0
General Advice: Seek medical attention for any exposure above minor irritation
Inhalation: Move person to fresh air immediately; provide oxygen or artificial respiration if breathing stops; consult a healthcare professional if symptoms persist
Skin Contact: Remove contaminated clothing and wash affected skin thoroughly with soap and water; if irritation occurs or persists, get medical attention
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes, lifting eyelids occasionally; contact an ophthalmologist
Ingestion: Rinse mouth; do not induce vomiting; offer water if the person is conscious; call poison control or your doctor right away
Symptoms of Exposure: Redness, pain, blistering (rare), coughing, headache, stomach upset
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, or foam
Specific Hazards: Toxic, irritating, and corrosive fumes of bromine and carbon oxides can form under fire conditions
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Special Precautions: Prevent run-off water from entering sewers or waterways
Explosion Data: No evidence of explosion risk under normal conditions, but dust can form explosive mixtures with air
Personal Precautions: Avoid contact with skin, eyes, and clothing; evacuate unnecessary personnel
Protective Equipment: Wear suitable gloves, protective clothing, and safety goggles; use a respirator where ventilation is inadequate
Cleanup Methods: Sweep up and place material in a suitable dry, sealed container for disposal; avoid dust generation; ventilate area
Environmental Precautions: Prevent spillage from entering soil, drains, or waterways; notify authorities if contamination occurs
Decontamination: Wash area thoroughly after removal of material; dispose of contaminated objects as hazardous waste
Handling: Use engineering controls or fume hood during transfer; avoid inhaling dust or vapor; wash hands before eating or drinking
Personal Protection: Wear gloves, long-sleeved clothing, and eye/face protection
Storage Conditions: Keep container tightly closed in a dry, cool, well-ventilated place; protect from light and moisture
Incompatibility: Store away from oxidizing agents, acids, and bases to prevent hazardous reactions
Storage Class: Chemical storage for hazardous, organic solids; lock and secure area where possible
Occupational Exposure Limits: ACGIH/TLV, OSHA/PEL not assigned for 4-Bromophenol; keep exposures as low as reasonably achievable
Engineering Controls: Use local exhaust ventilation or fume hood; ensure eye-wash and safety showers are available
Respiratory Protection: Use approved respirators if risk of inhalation
Skin Protection: Nitrile or neoprene gloves, lab coat, protective sleeves
Eye/Face Protection: Chemical safety goggles or face shield
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling; avoid eating, drinking, or smoking while using this product
Monitoring: Routine air monitoring in workplaces handling bulk amounts
Appearance: White or off-white crystalline solid
Odor: Phenolic, sharp odor
pH: Slightly acidic in solution
Melting Point: 63 - 67 °C
Boiling Point: 238 °C
Flash Point: 119 °C (closed cup)
Solubility: Slightly soluble in water; soluble in ethanol, ether, benzene
Density: 1.74 g/cm3
Vapor Pressure: Negligible at room temperature
Partition Coefficient (Log Kow): 2.46
Stability: Stable under recommended storage conditions
Chemical Stability: Stable under normal temperature and pressure
Reactivity: Reacts with strong oxidizing agents, strong acids, and strong bases
Hazardous Reactions: Violent reaction risk when combined with incompatible materials
Decomposition Products: Bromine, carbon monoxide, carbon dioxide, phenolic vapors upon combustion
Polymerization: No hazardous polymerization expected
Conditions to Avoid: Excess heat, open flames, exposure to light, moisture
Acute Toxicity: Oral LD50 (rat): 660 mg/kg
Skin Corrosion/Irritation: Moderate skin irritant in rabbit studies
Serious Eye Damage/Irritation: Irritating, risk of conjunctivitis with high doses
Respiratory Sensitization: May cause irritation on inhalation
Carcinogenicity: No classification by IARC, NTP, OSHA
Mutagenicity: No evidence in available studies
Reproductive Toxicity: Insufficient data
Chronic Exposure: May cause dermatitis, no documented systemic toxicity at occupational exposures
Target Organs: Skin, eyes, respiratory tract
Symptoms: Headache, dizziness, nausea with ingestion or high vapor exposure
Aquatic Toxicity: Harmful to aquatic organisms based on acute test data for fish and daphnia; acute EC50 (Daphnia magna): 1.1 mg/L (48 hr)
Persistence and Degradability: Not readily biodegradable; may persist under some environmental conditions
Bioaccumulation: Moderate potential (log Kow 2.46)
Soil Mobility: Limited, but risk of groundwater contamination exists with spills
Additional Info: Avoid release into the environment; follow best practices for chemical waste management
Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, and national regulations
Incineration: Preferred method in a chemical incinerator equipped with afterburner and scrubber
Contaminated Packaging: Treat as hazardous waste; recycle only if decontaminated
Avoid: Disposal to sewage systems, waterways, or open environment
Special Instructions: Consult with local, licensed chemical disposal service provider
UN Number: 2811
Shipping Name: Toxic solid, organic, n.o.s. (Contains 4-Bromophenol)
Transport Hazard Class: 6.1
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Toxic (Skull and crossbones)
Transport Precautions: Secure, avoid physical damage, carry separate from foodstuffs
Regulatory References: Compliant with international regulations (ADR/RID, IMDG, IATA)
TSCA: Listed on the US Toxic Substances Control Act (TSCA) Inventory
EINECS/ELINCS: Listed (203-397-0)
OSHA: Classified as hazardous based on OSHA criteria
SARA Title III: Not reportable under sections 302, 304, 313
California Proposition 65: Not listed
Other Inventories: Complies with Canadian DSL/NDSL, Australia AICS, Japan ENCS
Labeling: GHS-compliant hazard pictogram; hazard and precautionary statements present
