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Product Name: 4-Bromobenzenesulfonyl Chloride
Chemical Formula: C6H4BrSO2Cl
Synonyms: p-Bromobenzenesulfonyl chloride, 4-Bromobenzenesulphonyl chloride
CAS Number: 98-60-2
Recommended Use: Intermediate for organic synthesis, pharmaceutical development, laboratory research
Manufacturer Information: Consult product supplier for up-to-date information
Emergency Contact: Local poison control center or fire department
GHS Classification: Acute Toxicity (Oral), Skin Corrosion/Irritation, Serious Eye Damage/Irritation
Label Elements: Warning visuals: Corrosive, Exclamation Mark
Hazard Statements: Causes severe skin burns and eye damage; Harmful if swallowed, inhaled, or in contact with skin; May cause respiratory irritation
Precautionary Statements: Avoid all contact with eyes, skin, and clothing; Do not breathe dust or fumes; Use only with adequate ventilation; Keep away from water and incompatible materials
Chemical Name: 4-Bromobenzenesulfonyl Chloride
Concentration: 99% or greater
CAS Number: 98-60-2
Impurities: Typical lab reagent-grade impurities, not exceeding 1%
Skin Contact: Remove contaminated clothing. Rinse skin with running water for 20 minutes. Seek medical help if irritation persists.
Eye Contact: Flush eyes with water for 15 minutes. Hold eyelids apart. Get immediate medical attention.
Inhalation: Move person to fresh air. If breathing stops, provide artificial respiration. Seek medical help.
Ingestion: Rinse mouth with water; never induce vomiting. Call a poison center or doctor right away.
Most Important Symptoms: Coughing, severe irritation, burns to exposed tissues, eye pain or damage, breathing difficulty
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Do not use water since contact with water generates toxic fumes
Hazardous Combustion Products: Hydrogen bromide gas, sulfur oxides, hydrogen chloride fumes
Specific Hazards: Decomposition in fire releases corrosive and toxic gases
Protective Equipment: Full protective clothing, self-contained breathing apparatus
Special Procedures: Stay upwind, cool containers with water spray to prevent bursting, contain run-off to prevent environmental contamination
Personal Precautions: Evacuate spill area, ventilate, avoid breathing vapors or dust, wear chemical-resistant gloves and goggles
Environmental Precautions: Prevent entry into drains, watercourses, or soil, report significant releases to local authorities
Spill Cleanup Methods: Collect with inert, non-combustible absorbent (sand or vermiculite), scoop up, place in sealed container for disposal, thoroughly ventilate spill area, wash surfaces with copious water, avoid water activation during cleanup
Handling: Keep in tightly closed container, work in a chemical fume hood, avoid generating dust or aerosols, avoid direct contact with skin or eyes
Storage: Store in cool, dry, well-ventilated place; segregate from incompatible substances (strong bases, water, strong oxidizers); protect container from moisture; keep away from food, drink, and animal feed
Hygiene: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse
Exposure Limits: No established regulatory exposure limits; minimize workplace exposure
Engineering Controls: Use local exhaust ventilation, chemical fume hood
Personal Protective Equipment: Chemical-resistant gloves (nitrile, butyl rubber), tight-fitting safety goggles, lab coat or impervious suit, suitable respiratory protection for dust or fumes
Additional Protection: Eye wash fountain and safety shower in immediate area; do not eat, drink, or smoke in handling areas
Appearance: White to pale yellow crystalline solid
Odor: Pungent, irritating odor
pH: Not applicable (reacts strongly with water)
Melting Point: 69–71 °C
Boiling Point: Decomposes
Flash Point: Not available
Vapor Pressure: Not determined
Solubility: Reacts with water, soluble in organic solvents (chloroform, dichloromethane)
Density: 1.81 g/cm3
Stability: Unstable in moisture, stable when dry; decomposes on exposure to water/moisture, releasing toxic gases
Chemical Stability: Stable under dry, inert storage; decomposes in humid air or water
Reactivity: Reacts violently with water, alcohols, amines, strong bases; generates hydrogen bromide and sulfur dioxide
Conditions to Avoid: Moisture, heat, direct sunlight, incompatible materials
Hazardous Reactions: Vigorous exothermic hydrolysis
Hazardous Decomposition Products: Sulfur oxides, hydrogen bromide, hydrogen chloride gases
Acute Toxicity: May cause irritation or burns to mucous membranes and airway if inhaled; toxic by ingestion; moderate acute toxicity in rodents
Skin Corrosion/Irritation: Causes burns and ulceration on prolonged or repeated contact
Serious Eye Damage/Irritation: Contact leads to permanent eye injury or blindness
Respiratory Sensitization: Dust or fumes irritate respiratory tract
Chronic Effects: No confirmed long-term health effects, but repeated exposure increases risk of dermatitis and organ effects
Symptoms: Burning, redness, swelling, chemical burns, coughing, shortness of breath, eye damage
Aquatic Toxicity: Harmful to aquatic life due to sulfur and bromine content
Persistence and Degradability: Not readily biodegradable; decomposes slowly in environment
Bioaccumulative Potential: Limited bioaccumulation expected for parent compound
Mobility in Soil: Product reacts with moisture, forming corrosive, mobile acids
Other Adverse Effects: Release of hydrogen bromide can impact air quality near spillage sites
Waste Disposal: Treat as hazardous waste; separate from general trash; dispose of through licensed hazardous waste contractor
Methods: Do not pour down drain; incinerate with appropriate air pollution control; comply with local, regional, and national regulations
Contaminated Packaging: Triple rinse, puncture, label for hazardous materials, discard as chemical waste
UN Number: 3261
UN Proper Shipping Name: Corrosive Solid, Acidic, Organic, N.O.S. (contains 4-Bromobenzenesulfonyl chloride)
Transport Hazard Class: 8 (Corrosive materials)
Packing Group: II
Hazard Labels: Corrosive
Special Precautions: Store and transport in airtight containers; keep away from moisture; follow relevant international transport regulations (ADR, IMDG, IATA)
OSHA Status: Hazardous chemical under OSHA Hazard Communication Standard
TSCA Status: Listed or meets requirements for TSCA compliance
REACH Status: Not registered for EU use at industrial level; check latest regional compliance
SARA Title III: Not listed as Extremely Hazardous Substance
Other Regulations: Subject to national and international chemical safety requirements; label all containers clearly; follow lab, workplace, and transportation rules for handling corrosive and toxic substances
