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Product Name: 4-Bromo-2-Chlorofluorobenzene
Chemical Formula: C6H3BrClF
Synonyms: 1-Bromo-3-chloro-4-fluorobenzene
CAS Number: 57311-83-8
Recommended Uses: Laboratory research, chemical synthesis
Manufacturer/Supplier: Listed on purchase documents
Contact Number: Supplier/emergency contact on packaging
Emergency Overview: Clear to pale yellow liquid, sharp chemical odor
Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, Toxic by skin absorption, Causes skin irritation, Causes eye irritation, May cause respiratory tract irritation
Pictograms: Exclamation Mark, Health Hazard
Precautionary Statements: Avoid breathing vapors, Use only outdoors or in well-ventilated area, Wear protective gloves and eye protection, Wash thoroughly after handling, If inhaled: Remove person to fresh air, If in eyes: Rinse cautiously with water, Seek medical attention if you feel unwell
Chemical Name: 4-Bromo-2-Chlorofluorobenzene
CAS Number: 57311-83-8
Concentration: 98%–100%
Impurities: May contain trace level organic halides or reaction by-products as listed in batch specifications
Inhalation: Move to fresh air, maintain airway, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, flush skin with water for at least 20 minutes, avoid scrubbing, consult a physician if irritation develops
Eye Contact: Rinse cautiously with water for at least 20 minutes; remove contact lenses if safe, seek ophthalmologist
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical care, provide SDS to physician
Flammability: Not classified as highly flammable, may release hazardous gases on combustion
Suitable Extinguishing Media: Dry chemical powder, foam, carbon dioxide
Unsuitable Extinguishing Media: Water jet
Special Hazards: Gives off hydrogen halides (HCl, HF, HBr), carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemically resistant clothing
Firefighting Instructions: Cool fire-exposed containers with water spray, control runoff, isolate hazard area
Personal Precautions: Wear respirator, chemical splash goggles, protective gloves, prevent inhalation and contact
Environmental Precautions: Prevent further leakage or spillage if safe, do not allow product to reach drains, surface water, or soil
Methods for Containment: Cover spill with inert absorbent material (vermiculite, sand), scoop up and place in chemical waste container
Cleanup Procedures: Dispose of as hazardous waste, ventilate area, decontaminate surfaces with detergent solution
Safe Handling: Work in chemical fume hood, avoid direct contact, do not eat, drink, or smoke in areas where handled, wash hands thoroughly
Storage Conditions: Store in tightly closed original container, keep in cool, dry, well-ventilated area, away from sources of ignition or incompatible substances (strong oxidizers, bases)
Special Precautions: Prevent static discharge, keep away from heat and sunlight, store below 25°C or as per batch certificate, label clearly
Occupational Exposure Limits: No established OEL, workplace monitoring required
Engineering Controls: Use laboratory fume hood, mechanical ventilation for storage and dispensing
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles, lab apron, long sleeves
Respiratory Protection: Organic vapor respirator when exposure exceeds safe limits or during emergencies
Hygiene Measures: Remove contaminated clothing immediately, launder before reuse, keep emergency shower and eye-wash station accessible
Appearance: Clear to pale yellow liquid
Odor: Sharp, pungent, chemical aroma
Melting Point: -20°C (approximate)
Boiling Point: 184–187°C
Vapor Pressure: Less than 1 mmHg (20°C)
Solubility: Insoluble in water, soluble in organic solvents including acetone, chloroform, ether
Specific Gravity: 1.7–1.8 (water = 1)
Flash Point: >90°C (closed cup, typical)
Partition Coefficient (log P): Estimated 3.6
pH: Not applicable (neutral organic compound)
Viscosity: Low, typical of aromatic halides
Chemical Stability: Stable under recommended storage conditions
Possible Hazardous Reactions: Reacts vigorously with strong oxidizers, incompatibility with bases and strong acids
Decomposition Products: Hydrogen chloride, hydrogen bromide, hydrogen fluoride, carbon oxides
Conditions to Avoid: Heat, sunlight, open flame, static electricity, contact with incompatible materials
Polymerization: Not expected under normal storage and handling
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Harmful if swallowed, skin absorption leads to irritation and systemic toxicity, eye contact causes irritation, inhalation may result in respiratory irritation and CNS symptoms
Chronic Effects: Long term exposure may impact liver, kidneys, and central nervous system
Carcinogenicity: Not classified by IARC, NTP, ACGIH
Mutagenicity: Insufficient data for assessment
Reproductive Toxicity: Data lacking for specific conclusions
LD50 (Oral, rat): Estimated 250–500 mg/kg
Symptoms of Exposure: Drowsiness, headache, nausea, skin redness, lacrimation, coughing
Ecotoxicity: Highly toxic to aquatic organisms, risk of long-term adverse effects in aquatic environment
Persistence and Degradability: Not readily biodegradable, persistent in soil and sediments, expected to bioaccumulate
Mobility in Soil: Low water solubility, strong sorption to sediment and organic matter
Bioaccumulation: Potential for accumulation in aquatic organisms and food webs
Aquatic Toxicity Data: Fish LC50 (96 h): <1 mg/L (estimated from structural analogues)
Other Adverse Effects: Avoid release to the environment, follow national/international regulations
Waste Treatment Methods: Dispose of in accordance with national and local regulations, incineration recommended at licensed facility
Contaminated Packaging: Triple rinse, offer for recycling if possible, otherwise treat as chemical waste
Special Instructions: Do not dispose in drains or natural streams, use licensed hazardous waste collector
UN Number: 3082 (Environmentally hazardous substance, liquid, N.O.S.)
Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (4-Bromo-2-Chlorofluorobenzene)
Transport Hazard Class: 9
Packing Group: III
Marine Pollutant: Yes
Transport Labels Required: Miscellaneous dangerous goods, marine pollutant
Special Precautions: Protect from physical damage, secure containers, follow all transport regulations for hazardous materials
TSCA Status: Listed
REACH Status: Pre-registered or in the process of registration
SARA Title III (Sections 302/313): Listed as hazardous
California Proposition 65: Not listed as a known carcinogen or reproductive toxin
WHMIS Classification: D2B (toxic materials causing other toxic effects)
Other Regulations: Follow OSHA Hazard Communication Standard requirements, comply with applicable workplace safety and health acts, observe local water and environmental emissions controls
