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Chemical Name: 4-Amino-N,N-Dimethylaniline Oxalate
Chemical Formula: C8H12N2·C2H2O4
Common Uses: Research laboratories, dye intermediates, and analytical chemistry applications mostly encounter this compound. It turns up as a crystalline solid, usually pale in color, that sometimes finds a way into certain chemical reactions thanks to its useful amine group.
CAS Number: 123-33-1
Molecular Weight: 238.26 g/mol
Physical Hazards: Combustible, though not highly flammable; it may smolder and release irritating, sometimes toxic fumes if exposed to heat.
Health Hazards: Irritates the skin, eyes, and respiratory tract. Prolonged or repeated exposure can affect blood and kidneys, given its similarity to other aromatic amine compounds.
Environmental Hazards: Harmful if released to water systems; potential to affect aquatic organisms due to toxicity. Spills should be contained to reduce impact on the broader ecosystem.
Component: 4-Amino-N,N-Dimethylaniline, present as oxalate salt
Concentration: Typically pure or present at high percentages in laboratory use
Impurities: Typically low, though minor laboratory reagents or byproducts could be present depending on synthesis method
Inhalation: Move affected individuals to fresh air at once. If breathing stops, artificial respiration may be needed. Medical attention remains crucial since exposure to aromatic amines can be insidious.
Skin Contact: Remove contaminated clothing, rinse skin with running water and use mild soap. Fast action will help reduce the likelihood of irritation or sensitization.
Eye Contact: Flush eyes with water for several minutes. Seek medical advice if irritation doesn’t subside.
Ingestion: Avoid inducing vomiting. Rinse mouth with water and seek medical help promptly.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide. Direct streams can spread powder so gentle application works best.
Hazardous Combustion Products: May release nitrogen oxides, carbon oxides, and toxic aniline vapors as fire breaks down the material.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective gear to avoid inhaling hazardous fumes.
Personal Precautions: Gloves, goggles, and proper lab garb keep skin and eyes protected. Dust masks or respirators prevent inhalation of fine particulate.
Environmental Precautions: Avoid allowing the material to reach drains. Absorb spills with inert materials like dry sand or vermiculite and transfer to containers for disposal.
Cleaning Procedures: Sweep up gently to reduce dust. Wash affected area afterward to clear residual contamination.
Handling: Keep containers tightly closed in a ventilated space. Handle with care, avoid generating dust, and wash thoroughly after handling. Never eat, drink, or smoke around the material.
Storage: Cool, dry, well-ventilated location works best. Protect from excessive moisture or heat. Keep away from foodstuffs and incompatible substances.
Engineering Controls: Use in fume hoods or with adequate general ventilation. Work in controlled environments to reduce airborne exposure.
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles, and lab coats minimize risk. Use respiratory protection if airborne levels climb.
Hygiene Measures: Wash hands and exposed skin thoroughly after handling. Remove and wash contaminated clothing before reuse.
Appearance: Solid, often crystalline; can appear pale yellow to off-white
Odor: Faint aromatic smell, not usually overpowering
Solubility: Soluble in water due to oxalate salt form
Melting Point: Tends to melt above 150°C, though decomposition can begin earlier for impure samples
Boiling Point: Not well-defined since decomposition occurs before boiling
Vapor Pressure: Negligible at room temperature
Chemical Stability: Stable under recommended storage conditions
Incompatibilities: Strong oxidizing agents, acidic or basic reactive substances can cause hazardous reactions
Decomposition Products: Heating or reaction with incompatible substances may generate carbon monoxide, carbon dioxide, and nitrous compounds
Hazardous Polymerization: Not known to polymerize spontaneously
Routes of Exposure: Inhalation, ingestion, skin, and eye contact.
Potential Health Effects: Irritating to skin and mucous membranes. Repeated exposure affects blood, and animal studies point to some risk of carcinogenicity common to aromatic amines. No well-established safe exposure level, so applying the precautionary principle pays off.
Aquatic Toxicity: Aquatic organisms show sensitivity to aromatic amines, making run-off a real concern.
Persistence and Degradability: These compounds often stick around longer than is healthy in soil or water and can form hazardous breakdown products.
Bioaccumulative Potential: Potential for accumulation in organisms cannot be ruled out without targeted study; exercise care with disposal.
Waste Methods: Collect chemical waste for incineration or chemical destruction at a licensed hazardous facility. Domestic disposal causes downstream contamination.
Container Handling: Empty containers handle as hazardous waste; never reuse for food or drink storage.
Points to Consider: Attention to thorough cleaning and proper documentation protects against environmental and legal headaches.
Transport Classification: Not explicitly listed under major transport hazard codes, but treat as a laboratory chemical with restricted handling requirements.
Packaging: Clearly labeled, leak-proof containers minimize the chance of spread.
Special Handling During Transport: Store upright, protected from physical shock or shifting. Notify carriers of hazardous potential as a matter of precaution.
National Regulations: Countries that regulate aromatic amines list this compound for workplace monitoring and environmental restrictions. Consult local regulations for limits and required reporting.
Safety Standards: Many regions demand risk assessments and use of proper personal protective equipment in all professional encounters.
Documentation: Keeping records and following chemical hygiene plans matter for compliance and long-term safety.
