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Product Name: 3-Nitrophenol
Synonyms: m-Nitrophenol, meta-Nitrophenol
CAS Number: 554-84-7
Molecular Formula: C6H5NO3
Molecular Weight: 139.11 g/mol
Recommended Use: Laboratory reagent, intermediate for dyes and pesticides
Supplier Identification: Chemical suppliers, academic institutions, research labs
Emergency Phone Number: National poison control center or local emergency services
Address: Manufacturer or distributor address listed on label
Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, toxic in contact with skin, causes eye irritation, may cause respiratory irritation, toxic to aquatic life
Precautionary Statements: Avoid breathing dust or fumes, use protective gloves, wash thoroughly after handling, keep away from food and drink
Appearance: Pale yellow crystals or powder
Label Elements: Exclamation mark, skull and crossbones, environment
Chemical Name: 3-Nitrophenol
Synonyms: m-Nitrophenol
Percent Purity: ≥ 99%
Impurities: Possible traces of o-nitrophenol, p-nitrophenol
CAS Number: 554-84-7
EC Number: 209-070-9
General Advice: Remove contaminated clothing and shoes, provide fresh air
Inhalation: Move person into fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms appear (e.g., cough, headache, dizziness)
Skin Contact: Wash skin thoroughly with soap and water, remove contaminated clothing, seek immediate medical attention for skin irritation or pain
Eye Contact: Rinse cautiously with clean water for at least 15 minutes, keep eyelids open, remove contact lenses if present and easy to do, get medical help
Ingestion: Rinse mouth, do not induce vomiting, give water if conscious and alert, seek medical care right away
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Hazards from Combustion: Emits toxic fumes such as nitrogen oxides, carbon monoxide, carbon dioxide
Special Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective clothing
Fire Fighting Instructions: Ensure firefighters have access to safety showers, cool fire-exposed containers with water spray to prevent bursting, avoid runoff into waterways, use caution around spilled or leaking material
Hazardous Combustion Products: Nitrogen oxides, phenol vapors, possible unidentified toxic gases
Personal Precautions: Evacuate area, prevent skin and eye contact, use NIOSH-approved respirators, avoid inhaling dust, don gloves and goggles
Environmental Precautions: Prevent further leakage or spillage, keep out of drains, soil, and surface water
Methods for Cleaning Up: Scoop up dry material using nonsparking tools, avoid dust generation, place collected solid in tightly closed containers, clean area with detergent and water, ventilate area
Disposal Considerations: Place materials in appropriate hazardous waste containers, follow local, regional, and national disposal regulations
Safe Handling: Handle in an efficient fume hood, avoid breathing vapor or dust, do not get in eyes or on skin or clothing, wash thoroughly after use
Storage Conditions: Keep container tightly closed, store in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizers and reducing agents, keep away from food and drink, protect from physical damage
Special Requirements: Use corrosion-resistant containers, ensure labeling remains visible, control access to material storage areas
Engineering Controls: Chemical fume hood, safety shower, eye-wash stations, local exhaust ventilation
Personal Protective Equipment: Appropriate gloves (nitrile, neoprene), chemical safety goggles or face shield, lab coat or apron, NIOSH-approved respirator in cases of inadequate ventilation
Hygiene Measures: Wash hands and exposed skin before eating, drinking, or smoking, take off contaminated clothing and wash before reuse
Workplace Exposure Limit: No specific OSHA PEL or ACGIH TLV; minimize exposure and handle as hazardous
Appearance: Pale yellow crystalline solid, slight phenolic odor
Melting Point: 96 – 98°C
Boiling Point: 279°C
Solubility: Moderately soluble in water, highly soluble in alcohol and ether
pH: Slightly acidic in aqueous solution
Vapor Pressure: Negligible at ambient temperature
Density: 1.48 g/cm³
Flash Point: 180°C
Autoignition Temperature: Not determined
Explosion Limits: Not determined
Chemical Stability: Stable under normal conditions in a sealed container
Reactivity: Reacts with strong oxidizers, reducing agents, strong acids, and bases
Conditions to Avoid: Heat, flames, sparks, direct sunlight, moisture
Incompatible Materials: Alkali metals, strong reducing agents, strong oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, potentially toxic organic compounds
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Oral LD50 in rats: ~100 mg/kg; toxic in small amounts
Health Effects: May cause methemoglobinemia, with symptoms like headache, dizziness, cyanosis, drowsiness, incoordination, and rapid heart rate; may be fatal in cases of severe exposure
Skin Effects: Severe irritation, pain, redness, possible burns
Eye Effects: Severe irritation, redness, tearing, blurred vision
Chronic Effects: Prolonged or repeated exposure may cause liver and kidney injury
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, ACGIH, or OSHA
Sensitization: Not expected to cause sensitization
Aquatic Toxicity: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: May persist in the environment, capable of being degraded by microbial action under certain conditions
Bioaccumulation Potential: Moderate potential for bioaccumulation in organisms
Mobility in Soil: Relatively mobile, may leach to groundwater
Other Adverse Effects: Avoid release to the environment, significant risk to aquatic life
Safe Disposal Method: Collect and label as hazardous chemical waste, incinerate in a chemical incinerator equipped with afterburner and scrubber, do not dispose of in the environment or regular trash
Contaminated Containers: Rinse with water, triple rinse if possible, dispose of rinsate as hazardous waste
Legal Disposal Requirements: Comply with all applicable local, regional, national, and international regulations for hazardous chemicals
UN Number: UN2811
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (3-Nitrophenol)
Transport Hazard Class: 6.1 (Toxic Substance)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions for Transport: Avoid rough handling, keep containers tightly closed, ensure suitable secondary containment
Regulations: Complies with ICAO/IATA, IMO/IMDG, ADR/RID regulations
TSCA Inventory: Listed
SARA Title III, Sections 302 and 313: Subject to reporting under SARA 313 (Toxic Release Inventory: "Nitrophenol (all isomers)")
RCRA Status: Classified as hazardous waste (D code for acute toxicity)
OSHA: Regulated hazardous chemical
Canada WHMIS: Included (Toxic Material)
REACH Registration: Complies with European Union REACH regulations
Other Local and International Regulations: Subject to appropriate chemical reporting and handling restrictions worldwide
