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Product Name: 3-Nitrobenzenesulfonyl Chloride
Chemical Formula: C6H4NO5SCl
CAS Number: 636-73-7
Use: Intermediate in organic synthesis, pharmaceuticals, dyes, agrochemicals
Manufacturer Contact Information: Fill in with local provider or responsible safety officer
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Hazard Classification: Causes severe skin burns and serious eye damage; Harmful if inhaled, swallowed, or in contact with skin
Signal Word: Danger
Hazard Statements: Corrosive to eyes, skin, and respiratory system; Harmful if swallowed or inhaled; May cause severe irritation to mucous membranes
Precautionary Statements: Do not breathe dust, vapors or spray; Wear appropriate protective gloves, goggles, face protection; Wash contaminated skin thoroughly after handling
GHS Label Elements: Corrosive pictogram, exclamation mark indicating irritation risk; Respiratory hazard indicated
Chemical Name: 3-Nitrobenzenesulfonyl Chloride
Synonyms: m-Nitrobenzenesulfonyl chloride
Content: >98% pure
Impurities: Minor impurities may include trace aromatic sulfonic acids
Molecular Weight: 237.63 g/mol
Inhalation: Move exposed person to fresh air. Seek immediate medical attention. Oxygen or artificial respiration if breathing stops. Remove any contaminated clothing.
Skin Contact: Immediately wash with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Seek urgent medical care for burns or blisters.
Eye Contact: Rinse cautiously with water for several minutes, lifting upper and lower eyelids. Remove contact lenses quickly if present and easy to do so. Get medical help immediately.
Ingestion: Rinse mouth, do not induce vomiting. Immediate medical advice required. Give water only if person is alert. Do not give anything by mouth to an unconscious person.
Main Symptoms: Burning pain, irritation, cough, breathing difficulty, red skin, severe eye injury possible.
Suitable Extinguishing Agents: Use carbon dioxide, dry chemical powder, foam; avoid water if possible to prevent violent reaction
Special Hazards: Produces toxic and irritating fumes such as HCl, SO2, NOx under fire; Releases corrosive and toxic gases on contact with moisture
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full chemical suit, boots, and gloves
Other Notes: Approach upwind to avoid vapors and protect downwind personnel. Runoff from firefighting may pose pollution risk.
Personal Precautions: Wear chemical-resistant gloves, protective clothing, tightly fitting goggles, and suitable respiratory protection; Remove ignition sources
Environmental Precautions: Prevent material from entering watercourses, drains, and soil; Inform authorities if environmental contamination occurs
Containment and Cleanup: Ventilate area, avoid raising dust, use inert absorbent (sand or vermiculite), scoop up carefully and place in a secure chemical waste container, avoid water
Decontamination: Wash contaminated surfaces with sodium bicarbonate solution to neutralize; Dispose according to local guidelines
Handling: Work in a chemical fume hood; keep container tightly closed; avoid breathing vapors or dust; do not eat, drink, or smoke while handling; use non-sparking tools
Storage: Keep in dry, cool, well-ventilated environment, away from incompatible materials (e.g., damp air, alcohols, amines, bases, strong oxidizers); use corrosion-resistant containers; segregate from food and feed products
Incompatibilities: Strong bases, strong acids, reducing agents, water, moisture; contact with water may cause violent reaction
Control Parameters: No established occupational exposure limits; minimize exposure through engineering practices
Engineering Controls: Chemical fume hood, emergency eyewash station, and safety shower within immediate area
Personal Protective Equipment: Chemical splash goggles; faceshield for high risk; acid-proof gloves (nitrile, neoprene, butyl); lab coat and apron; suitable respirator for dust or fume exposure
Hygiene Measures: Wash hands and face before breaks and end of work. Do not take contaminated clothing home.
Appearance: Pale yellow to off-white crystalline powder
Odor: Pungent, acrid
Melting Point: Approx. 78–80°C
Boiling Point: Decomposes before boiling
Solubility: Reacts with water, hydrolyzes forming sulfonic acid and HCl
Vapor Pressure: Not significant at room temperature
Flash Point: Data not available, but combustible
Relative Density: Approx. 1.7 g/cm³
pH: Not applicable (reacts in water)
Partition Coefficient: Data not available
Other Data: Decomposes in contact with acids, bases, moisture, or strong oxidizers
Chemical Stability: Stable if kept dry and sealed under inert conditions
Conditions to Avoid: Moisture, heat, open flames, sunlight
Materials to Avoid: Strong bases, alcohols, amines, water, oxidizing and reducing agents
Hazardous Decomposition: Hydrochloric acid, sulfur oxides, nitrogen oxides, nitrosyl chloride, toxic fumes
Polymerization: No reported hazardous polymerization
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms of Exposure: Severe skin and eye burns, ulceration, coughing, difficulty breathing, gastrointestinal pain, vomiting
Acute Toxicity: Limited published data; moderate acute oral and inhalation toxicity expected
Chronic Effects: Prolonged exposure could lead to dermatitis, respiratory tract impairment, possible lung sensitization
LD50 (oral, rat): Not well established, but presumed harmful.
Carcinogenicity: No current data suggest carcinogenic potential. No NTP, IARC, or OSHA categorization.
Sensitization: May produce allergic reactions in sensitive individuals on repeated skin contact.
Toxicity: Harmful to aquatic organisms; may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Hydrolyzes and breaks down in moist conditions but products remain problematic
Bioaccumulation: Not expected to bioaccumulate significantly; data insufficient
Mobility in Soil: Likely to be immobile under dry conditions but decomposes with water
Other Adverse Effects: Contributes to acidification and chemical pollution if released in quantity
Waste Treatment: Collect in clearly labeled, tightly sealed containers; store in a secured area prior to disposal
Disposal Method: Incinerate in a controlled chemical waste facility; do not attempt to neutralize large amounts in drains
Contaminated Packaging: Dispose of as hazardous chemical waste; do not reuse or recycle
Regulatory Compliance: Follow local, regional, and national regulations for hazardous waste
UN Number: 3261
Proper Shipping Name: Corrosive Solid, Acidic, Organic, N.O.S. (contains 3-Nitrobenzenesulfonyl chloride)
Hazard Class: 8 (Corrosive)
Packing Group: II
Transport Labels: Corrosive (Class 8)
Special Precautions: Avoid moisture, protect from physical damage, secure packaging; ensure transport personnel are informed and equipped
Environmental Hazards: Not marine pollutant under standard definitions, but must avoid exposure to water bodies during emergency
Occupational Safety: OSHA hazardous chemical; use controls and PPE as detailed in workplace regulations
Inventory Listing: Registered under TSCA (United States); meets requirements for chemical safety in REACH (EU) for research; check country-specific requirements
Label Requirements: GHS-compliant labeling, including danger pictograms, signal words, hazard and precautionary statements
Other Regulations: Comply with workplace exposure and environmental release restrictions; maintain records and safety documentation as specified by authority
Community Right-to-Know: Report to relevant local or state agencies if handling large quantities or releasing in any way
